Your heart has four valves. Normally, these valves open to let blood flow through or out of your heart, and then shut to keep it from flowing backward. But sometimes they don't work properly. If they don't, you could have
- Regurgitation - when blood leaks back through the valve in the wrong direction
- Mitral valve prolapse - when one of the valves, the mitral valve, has "floppy" flaps and doesn't close tightly. It's one of the most common heart valve conditions. Sometimes it causes regurgitation.
- Stenosis - when the valve doesn't open enough and blocks blood flow
Valve problems can be present at birth or caused by infections, heart attacks, or heart disease or damage. The main sign of heart valve disease is an unusual heartbeat sound called a heart murmur. Your doctor can hear a heart murmur with a stethoscope. But many people have heart murmurs without having a problem. Heart tests can show if you have a heart valve disease. Some valve problems are minor and do not need treatment. Others might require medicine, medical procedures, or surgery to repair or replace the valve.
NIH: National Heart, Lung, and Blood Institute
Heart Disease FDA Approved Drugs
- Treatment of pediatric patients 8 to 17 years of age with heterozygous familial hypercholesterolemia (hefh).
- Use of rosuvastatin calcium for the primary prevention of cardiovascular disease in individuals without clinically evident coronary heart disease but with increased risk factors.
- Use of rosuvastatin calcium to reduce elevated total-c, ldl-c, apob, nonhdl-c or tg levels; to increase hdl-c in adult patients with primary hyperlipidemia or mixed dyslipidemia; and to slow the progression of atherosclerosis..
- Management of risk of dronedarone/beta-blocker interaction in patients in sinus rythm with a history of paroxysmal or persistent af.
- Reduction in risk of hospitalization in patients with a history of paroxysmal or persistent af without severe heart failure and with one or more risk factors by administration twice a daily with morning and evening meals.
- Reduction in risk of hospitalization in patients with coronary heart disease and a history of paroxysmal or persistent af and with one or more risk factors by administration twice a day with morning and evening meals.
- Reduction in risk of hospitalization in patients with stable nyha class iii heart failure and a history of paroxysmal or persistent af and with one or more risk factors by administration twice a day with morning and evening meals.
- Reduction of the risk of cardiovascular hospitalization.
- Reduction of the risk of hospitalization for atrial fibrillation.
- Treatment of patients with a history of paroxysmal or persistent af without severe heart failure and with one or more risk factors by administration twice a day with morning and evening meals.
Felter's Materia Medica on Heart Disease
...e cardiac nerve centers, or when arising from organic lesions. It is best adapted to those forms of heart disease characterized by irritability, irregularity, and weakness, with dyspnea and praecordia......nder its administration. It quickly relieves the suffering and anxiety nearly always experienced in heart diseases; and is of especial value to relieve the rapid heart action of excessive smokers. Lyc...1
The dried ripe seeds of Strophanthus Kombé, Oliver, or of Strophanthus hispidus, DeCandolle, deprived of their long awns (Nat. Ord. Apocynaceae).... / ...gly endorsed in heart affections with disorders of compensation. Strophanthus is useful in valvular heart disease only so far as there is muscular insufficiency, where the compensatory increase of mu...1
Physician's Therapeutics Memoranda on Heart Disease
In organic diseases of the heart. remedies must be adapted to symptoms presented. Digitalis and similar agents are to be used when increase of blood pressure is desired; strophanthus when increas ed pressure will do harm, while yet an arterial stimulant is needed; nitroglycerin to diminish arterial tension, aconite when the heart’s action is excessive. Functional disturbance of the heart calls for cardiac tonics when it arises from weakness, aconite in the rarer cases where the heart has been ...2
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.