Roxicodone
What are opioids?
Opioids, sometimes called narcotics, are a type of drug. They include strong prescription pain relievers such as oxycodone, hydrocodone, fentanyl, and tramadol. The illegal drug heroin is also an opioid.
A health care provider may give you a prescription opioid to reduce pain after you have had a major injury or surgery. You may get them if you have severe pain from health conditions like cancer. Some providers prescribe them for chronic pain.
Prescription opioids used for pain relief are generally safe when taken for a short time and as prescribed by your provider. However, people who take opioids are at risk for opioid use disorder (OUD) and overdose. These risks increase when these medicines are misused. Misuse can include taking more than your prescribed dose or taking it more often, using it to get high, or taking someone else's opioids.
What is an opioid overdose?Opioids affect the part of the brain that regulates breathing. When people take high doses of opioids, it can lead to an overdose, with the slowing or stopping of breathing and sometimes death.
What causes an opioid overdose?An opioid overdose can happen for a variety of reasons, including if you:
- Take an opioid to get high.
- Take an extra dose of a prescription opioid or take it too often (either accidentally or on purpose).
- Mix an opioid with other medicines, illegal drugs, or alcohol. An overdose can be fatal when mixing an opioid and certain anxiety treatment medicines, such as Xanax or Valium.
- Take an opioid medicine that was prescribed for someone else. Children are especially at risk of an accidental overdose if they take medicine not intended for them.
There is also a risk of overdose if you are getting medications for opioid use disorder (MOUD). MOUD is a treatment for OUD. Many of the medicines used for MOUD are also controlled substances that can be misused.
Who is at risk of an opioid overdose?Anyone who takes an opioid can be at risk of an overdose, but you are at higher risk if you:
- Take illegal opioids
- Take more opioid medicine than you are prescribed
- Combine opioids with other medicines and/or alcohol
- Have certain medical conditions, such as sleep apnea, or reduced kidney or liver function
- Are over 65 years old
The signs of an opioid overdose include:
- Very small pupils of the eyes
- Falling asleep or loss of consciousness
- Slow, shallow breathing
- Choking or gurgling sounds
- Vomiting
- Limp body
- Pale, blue, or cold skin
- Faint heartbeat
- Purple lips and fingernails
If you think someone is having an opioid overdose:
- Call 911 immediately.
- Give the person naloxone, if it is available. Naloxone is a safe medication that can quickly stop an opioid overdose. There are two forms. One is a nasal spray that you spray info the nose. The other type is injected into the muscle under the skin, or into the veins. Naloxone works by blocking the effects of the opioids on the body. It's important to read the product instructions and check the expiration date before you give it to someone.
- Try to keep the person awake and breathing.
- Lay the person on their side to prevent choking.
- Stay with the person until emergency workers arrive.
Naloxone won't harm someone if they're overdosing on drugs other than opioids, so it's best to use it if you think someone is overdosing.
Can an opioid overdose be prevented?If you are taking opioid pain medicine, there are steps you can take to help prevent an opioid overdose:
- Take your medicine exactly as prescribed by your provider. Do not take more medicine at once or take medicine more often than you are supposed to.
- Never mix the pain medicines with alcohol, sleeping pills, or illegal substances.
- Store your medicine safely where children or pets can't reach it. Consider using a medicine lockbox. Besides keeping children safe, it also prevents someone who lives with you or visits your house from stealing your medicines.
- Dispose of unused medicine promptly.
It is also important to teach your family and friends how to respond to an overdose. If you are at higher risk of an overdose, you will want get naloxone and carry it with you wherever you go. You can buy naloxone at a pharmacy.
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nih-developed Ai Algorithm Matches Potential Volunteers To Clinical Trials
researchers From Nlm And The National Cancer Institute Have Developed An Artificial Intelligence (ai) Algorithm To Help Speed Up The Process Of Matching Potential Volunteers To Relevant Clinical Research Trials Listed On Clinicaltrials.gov. A Study Published In nature Communications Found That The Ai Algorithm, Called Trialgpt, Could Successfully Identify Relevant Clinical Trials For Which A Person Is Eligible And Provide A Summary That Clearly Explains How That Person Meets The Criteria For Study Enrollment. The Researchers Concluded That This Tool Could Help Clinicians Navigate The Vast And Ever-changing Range Of Clinical Trials Available To Their Patients, Which May Lead To Improved Clinical Trial Enrollment And Faster Progress In Medical Research.
research At Nlm
nlm Division Of Intramural Research
Intramural Research At Nlm Consists Of The Development And Application Of
Computational Approaches To A Broad Range Of Problems In Biomedicine, Molecular Biology, And Health.
read Research Highlights | Meet Our Principal
Investigators | Explore Training
Opportunities
history Of Medicine At Nlm
biomedical And Clinical Informatics At Nlm
-
Efficient Health Care Information Exchange In The Us And Worldwide Is Made Possible By Nlm’s Work With It Data Standards.
-
This Set Of Tooling Services Brings Together Many Health And Biomedical Vocabularies And Standards To Enable Interoperability Between Computer Systems.
-
This Training Program Provides Biomedical And Clinical Informatics Training And Research Opportunities For Individuals At Various Stages In Their Career.
about Nlm
-
The Library Started As A Shelf Of Books In The Surgeon General’s Office In 1836 But Has Grown To A Collection Of Millions Of Print And Electronic Resources.
-
The Diverse Centers, Divisions, Advisory Bodies And Other Organizational Units That Make Up Nlm Contribute In Myriad Ways To The Library’s Mission.
-
this Ten Year Plan Outlines Nlm's Role In A Future Where Data And Information Transform And Accelerate Biomedical Discovery And Improve Health And Health Care.
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- Management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate..