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WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Felter's Materia Medica on Copaiba

COPAIBACOOF2
   An oleoresin derived from species of Copaiba growing in South America. Dose, 5 to 30 drops. Description.—A viscid, pale-yellow or brownish-yellow liquid, without or with a faint fluorescence (green), and having a bitter, acrid, and persistent taste, and a distinctive aroma. Soluble in chloroform, ether, dehydrated alcohol, and volatile or fixed oils; partly soluble in alcohol; insoluble in water. Specific Indications.—Vesical pressure and tenesmus, frequent urging to urinate, the urine passing in drops; itching, burning or smarting in the urethra after urinating; urethral mucoid discharges; laryngeal irritation; cough, with thick tenacious sputum, accompanied by loud rales. Action.—Copaiba is a stimulating antiseptic when applied to the skin and mucosa. Small doses taken internally act as a stimulant and antiseptic diuretic. It restrains excessive mucous discharges. When swallowed it causes gastric warmth, unpleasant eructations, and sometimes nausea and vomiting. Continued use impairs the digestive processes. It is readily absorbed, imparting its odor and bitterness to the secretions. While apparently eliminated by all the emunctories, it is chiefly passed in the urine in company with glycouronic acid. Large doses occasion gastroenteritis and haematuria. A transient measleslike eruption on the skin, with unpleasant formication and itching, or an erythematous, urticarial or bullous outbreak may occur from its use. It is not determined whether this is due to elimination-irritation, or to gastric disturbances produced by the drug. Therapy.—External. Copaiba is sometimes applied to frost-bites and chilblains, sore nipples, old ulcers, and anal fissures, and to fistulous tracts to soften hardened edges and surfaces; also in sluggish chronic skin affections when a stimulating antiseptic action is desired. Internal. Copaiba is a remedy for excessive mucous discharges after the subsidence of acute inflammation. For this purpose it is rarely used in chronic bronchitis, especially when coincident with a catarrhal condition of the bladder. It is of much value in intractable gonorrhea in the male to reawaken a dormant infection and recreate the active symptoms, after which the smaller doses are used to restrain the discharge and antisepticize the membranes. It should never be used in the acute inflammatory stage of gonorrhea, with pronounced urethral irritation and profuse secretion. This stage should be treated with Rx. Specific Medicine Aconite, 10 drops; Specific Medicines Gelsemium and Cannabis, one fluidrachm each; Simple Syrup, enough to make 4 fluidounces. Mix. Sig.: One teaspoonful every 3 hours. Having used the required local application, and rendered the urine bland by the use of small doses of sodium bicarbonate well diluted, employ the following after the acute phase has subsided: Rx Copaiba, 1 fluidrachm; Alcohol, 1 fluidounce. Mix. Dose, 5 to 10 drops in sugar and water 4 times a day. If chronic or unduly prolonged use the following: Rx. Copaiba and Spirit of Nitrous Ether, 1/2 fluidounce each; Liquor Potassae and Essence of Cinnamon, 1 fluidrachm each; Mucilage of Acacia and Simple Syrup, 1 fluidounce each. Mix. Sig.: One teaspoonful after each meal. Copaiba only helps gonorrhea when brought in direct contact with the parts affected, as it does when passed in the urine. For this reason it is more effectual in the male than the female in whom at least a part of the infection is vaginal. It is also less valuable by injection than when used internally. The foregoing treatment is Locke’s method, and is adapted to otherwise unconquerable cases. Most cases of gonorrhea are now readily cured by more modern means.1

OLEUM SANTALI
   Oil of Santal, Oil of Santal Wood, East Indian Oil of Santal, Oil of Sandalwood. A volatile oil distilled from the wood of Santalum album, Linné (Nat. Ord. Santalaceae). A small tree of southern India and the Indian Archipelago. Description.—A pale yellow, thickish, oily liquid having the taste and odor characteristic of sandalwood; soluble in alcohol. Dose, 1 to 15 drops. Principal Constituent.—An alcohol santalol (C15H26O) Action and Therapy.—Oil of santal closely duplicates the effects of oil of copaiba and oil of cubeb, and will sometimes cause gastro-intestinal disturbances. It is, however, less irritant and pleasanter to take than those oils. It may occasion a red papular eruption upon the skin and the conjunctivae. Oil of santal is eliminated chiefly by the urinary and bronchial tracts, acting upon them as a stimulant and disinfectant. It is chiefly used in gonorrhea after the active stage has passed. Occasionally it is employed in chronic bronchitis and bronchial catarrh with fetid expectoration, in pyelitis, chronic cystitis, chronic mucous diarrhoea, and in urethral hemorrhage.1


References

1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.