HUMULUS
   The strobiles of Humulus Lupulus, Linné (Nat. Ord. Urticaceae). Europe and Asia; common in cultivation. Common Names: Hops, Hop. Principal Constituents.—Lupulin (see Lupulinum), hop-bitter acid, humulitannic acid, resins, volatile oil and asparagine, trimethylamine, and choline. Preparation.—Specific Medicine Humulus. Dose, 1 to 60 drops. Specific Indications.—(See Lupulinum.) Action and Therapy.—External. A “hop-pillow” is a favorite device for procuring sleep. The odor of the hop has a decidedly sedative influence upon some individuals, relieving headache and producing sleep; in others it produces intense headache, with nausea and vomiting. Probably the psychic effect has much to do with its value in insomnia. A hot "hop bag" applied to the face is a favorite domestic cure for neuralgic face ache, and a “hop poultice” has anodyne properties. Internal. This is a remedy to relieve nervous excitability in fevers and to induce sleep. It also checks fermentation of the stomach contents and thus proves useful in fermentative dyspepsia with acid eructations. For other uses see Lupulinum, which has superseded hops largely as an internal medicine.¹

LUPULINUM
   Lupulin. The glandular powder separated from the strobiles of Humulus Lupulus, Linné (Nat. Ord. Cannabaceae), the common Hop. (See Humulus.) Description.—Brownish-yellow (becoming yellowish-brown), resinous granules, having the aromatic odor and bitter taste of hops. It is readily inflammable, and deteriorates upon long keeping. Dose, 5 to 20 grains in capsule or pill. Preparation.—Specific Medicine Lupulin. Dose, 5 to 30 drops. Specific Indications.—Nervousness, irritability, disposition to brood over trouble, delirium, insomnia, cerebral hyperemia; genital and mental irritability associated with spermatorrhea; fermentative dyspepsia, with acid eructations. Action and Therapy.—Lupulin is administered in disorders for which infusion and tincture of hops were formerly given. It is a remedy for nervousness, to allay irritation and to produce sleep. It gives a sense of mental tranquillity which makes it a valuable agent in nervous unrest due to nocturnal seminal emissions, and relieves irritation of the genital tract when associated with the latter. It relieves irritation of the bladder, with frequent urination, and is quite efficient in chordee. When delirium tremens is accompanied by cerebral hyperemia it is of considerable service. Insomnia due to nervous debility or to worry, or headache associated with active cerebral circulation, is benefited by lupulin; while for painful conditions it may be employed when they depend upon nervous debility. For the latter reason it has been given with success in dysmenorrhea, and other painful conditions of the uterus and in after-pains. Lupulin checks fermentative changes in the stomach, thus proving useful in yeasty indigestion with acid eructations and dilation of the stomach, and in the headache due to such gastric disturbance.¹