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WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Felter's Materia Medica on Cinnamomum

CAMPHORA
   A stearopten (having the nature of a ketone) derived from Cinnamomum Camphora. (Linné), Nees et Ebermeier (Nat. Ord. Lauraceae). China and Japan. Common Names: Camphor, Laurel Camphor, Gum Camphor (it is not a gum). Description.—Tough, translucent white lumps or granules, having the pungent taste known as camphoraceous, and an aromatic penetrating odor. It dissolves freely in alcohol, chloroform, ether, and fixed and volatile oils; very slightly in water. Camphor is readily pulverized by triturating it with a few drops of alcohol, chloroform, or ether. Dose (by mouth), 1 to 5 grains; (hypodermatically) 1 to 3 grains. Preparations.—1. Spiritus Camphorae (10 per cent), Spirit of Camphor. Dose, 1 to 30 drops. 2. Aqua Camphorae. Camphor Water. Dose, 1 to 4 fluidrachms. 3. Linimentum Camphorae. Camphor Liniment (Camphorated Oil) (Composed Of Camphor, 200 parts; Cottonseed Oil, 800 parts). Dose, 10 to 30 drops. For external use chiefly. 4. Ceratum Camphorae. Camphor Cerate. (Composed of Camphor Liniment, White Wax, White Petrolatum, and Benzoinated Lard.) For external use. Action.—Camphor causes a local dilation of the capillaries of the skin, producing warmth, redness, and sometimes itching. Slight anesthesia follows. It causes smarting and hyperaemia of the mucosa, and if applied strong may cause considerable irritation. In this manner it has produced gastric ulceration. In small doses camphor warms the stomach, stimulates secretion, increases peristalsis, and expels flatus. Large doses may induce vomiting. Camphor is readily absorbed, both from application and inhalation. It is largely changed in the body and is eliminated in the urine as campho-glycuronic acid. In moderate doses camphor directly stimulates the heart-muscle, causing slower and stronger contractions and increased arterial pressure, but after large doses the pressure falls. Respiration is slightly stimulated by it, large doses causing slower and deeper breathing. In general it may be said that small doses of camphor stimulate, while large quantities depress, or even paralyze. This is true of all the functions it affects. The action of small doses upon the nervous system is to produce a feeling of slight exhilaration or contentment. Large doses excite the higher cerebral and medullary centers and then paralyze them; poisonous doses occasioning more or less of the following symptoms: esophageal and gastric pain, vomiting, headache, dizziness, mental confusion, drowsiness, delirium, and stupor; feeble, running, or intermittent pulse, cold skin, cold sweat, and muscular weakness followed by rigidity and epileptiform. convulsions, collapse and death. The type of convulsions shows its effects to be chiefly upon the cerebral cortex, though it acts also progressively on the medulla, causing death by respiratory paralysis. Camphor does not affect all persons alike. Some may pass directly into drowsiness, insensibility, and stupor, followed by death. If taken for long periods, even in moderate doses, camphor gives rise to a state of mental confusion. Opium and repeated small doses of alcohol are the best antagonists of the untoward effects of camphor. Therapy.—External. Camphor is stimulant, rubefacient, antipruritic, and feebly antiseptic. Owing to its agreeable odor and pleasant stimulating effects it is largely used, as a powder, in lotions, and ointments, or rubbed up with other solids to produce anodyne and antiseptic liquids. In this manner, when triturated with chloral hydrate, menthol, phenol, thymol, and similar bodies, ideal liquid antiseptics are obtained for use upon wounds, neuralgic and other painful areas. Powdered camphor is an ingredient of tooth powders and pastes and dusting powders for skin diseases. Alone or with zinc oxide, talc, or precipitated chalk it may be used upon bed-sores with decided relief. Such combinations are valuable in intertrigo, chronic eczema, urticaria, and zoster. Many snuffs contain powdered camphor, and it is useful to stimulate sluggish ulcers. Sprinkled upon the face it is used to control itching and to prevent pitting in small-pox. The spirit is a household embrocation for the relief of pain and itching, and it is used largely, alone, or in liniments and embrocations, for the relief of pain, stiffness, soreness and swelling, as in myalgia, facial and other neuralgias, and upon rheumatic joints, deep inflammations, chronic indurated glands and other indurations, sprains, contusions, and inflammatory swellings. An ethereal tincture of camphor is said to give relief in erysipelas. Inhaling the spirit, or camphor dropped into hot water, gives relief in nervous headache, and often aborts acute colds, coryza, and influenza, giving respite from the excessive secretion and the accompanying headache. A solution of camphor in liquid petrolatum (usually with menthol) is a popular spray for similar uses, and for laryngitis, pharyngitis, chronic nasal catarrh and hypertrophic rhinitis. The spirit, the liniment, or camphorated oil are favorite applications for tenderness and pain, chilblains, toothache, and acute mastitis: in the latter it tends to suppress the milk. The spirit is in common use as a lotion for headache in nervous individuals with feeble circulation, and tendency to fainting. The oil, by injection, is sometimes effectual in removing seatworms. So-called “camphor-ice” is a soothing, camphorated petrolatum preparation for labial herpes. Internal. Camphor is used to allay nervous excitement, subdue pain, arrest spasm, and sometimes to induce sleep. It is an important remedy in many disorders of neurotic women and children, being frequently most effective as a nerve sedative, antispasmodic, and carminative in nervous nausea and vomiting, flatulence, hiccough, and tendency to spasms or fainting. It is especially serviceable in palpitation of the heart due to gaseous distention of the stomach, or to nervous irritability. In occipital headache, from mental strain, or overstudy, small doses of 1

CINNAMOMUM
   I. Cinnamomum Saigonicum. Dried bark of an undetermined species of Cinnamomum. Chiefly from China. II. Cinnamomum Zeylanicum. Dried bark of cultivated Cinnamomum zeylanicum, Breyne. (Nat. Ord. Lauraceae.) Ceylon. Common Names: Cinnamon; (1) Saigon Cinnamon; (2) Ceylon Cinnamon. Principal Constituents.—A volatile oil (Oleum Cinnamomi), tannin, and sugars. (Oil of Cinnamon of medicine is Cassia Oil (Oleum Cassiae) derived from Cinnamomum Cassia (Nees), Blume.) Preparations.—1. Specific Medicine Cinnamomum. Dose, 5 to 60 drops. 2. Oleum Cassiae, Oil of Cinnamon (Cassia Oil), a yellowish or brownish fluid becoming darker and denser by age and exposure, and having the odor and taste of cinnamon. Dose, 1 to 5 drops. Specific Indications.-Passive hemorrhages. Action and Therapy.—Cinnamon is an aromatic stimulant, carminative and astringent. Besides it possesses marked internal hemostatic power. That this is not wholly due to the tannin contained in the bark is shown by the prompt action of the tincture of the oil. Oil of Cinnamon has properties which make it nearly specific for certain conditions. While no tests have been made that convinces one of its power over germ-life, there seems to be no question that some such germicidal action is exerted by it in acute infections, as “common colds,” and as la grippe or epidemic influenza. Aromatic bodies, like cinnamon and camphor, have been overlooked in recent years, though the use of the latter has been revived as an antiseptic stimulant in pneumonia. That they possess antibacterial virtues we believe will be found true should investigations be made of them in that line. Cinnamon imparts a flavor to unpleasant medicines and may be used to preserve them from rapid changes. Medicines dispensed in but few drops in a half glass of water will not keep sweet long at any time and will quickly sour in summer time. A few drops of Specific Medicine Cinnamon added to such mixtures give an agreeable sweetness and aroma and will help the medicine to preserve its balance for several days. Children invariably like the flavor. Even cinnamon can be overdone, however. It should not be added day after day for a long period lest the stomach revolt and the taste recoil. Nor should much be put in mixtures for little children, for if overdone it smarts the mouth severely; nor should it be employed when the mouth is irritated or ulcerated. When too much has been added the oil of cinnamon separates and floats upon the surface, and if thus given it is decidedly irritant. If the medicine to which it has been added in over-amount is too valuable to throw away, the excess of cinnamon may be easily removed by lightly sweeping over the surface with a clean piece of bibulous paperblotting paper or filter paper-or a firm, non-crumbling piece of bread. Cinnamon is frequently employed as an ingredient of mixtures to restrain intestinal discharges, and the powder with or without chalk or bismuth, or its equivalent in infusion has long figured in the treatment of diarrhea and acute dysentery, though it does not equal in the latter condition other agents which we now use specifically. In diarrhea it should be used in small doses if of the acute type, and in large doses in chronic noninflammatory and non-febrile forms. It warms the gastro- intestinal tract and dispels flatus, being decidedly useful as a carminative. It has the advantage of preventing griping when given with purgatives, and it enters into the composition of spice poultice, a useful adjuvant in the treatment of some forms of gastro-intestinal disorders. Cinnamon has been proved in Eclectic practice to be a very important remedy in hemorrhages. It acts best in the passive forms. The type of hemorrhage most benefited is the post-partum variety, though here it has its limitations. If the uterus is empty and the hemorrhage is due to flaccidity of that organ due to lack of contraction, then it becomes an important agent. Then it strongly aids the action of ergot and should be alternated with it. If retained secundines are the provoking cause of the bleeding, little can be expected of this or any other agent until the offenders have been removed. Cinnamon should be frequently given, preferably a tincture of the oil, though an infusion might be useful, but it cannot be prepared quickly enough or be made of the desired strength. Specific Medicine Cinnamon is a preferred preparation. Oil of erigeron acts very well with it. In menorrhagia, even when due to fibroids and polypi, it has had the effect of intermittently checking the waste: but only a surgical operation is the rational course in such cases. Other hemorrhages of a passive type are benefited by cinnamon. Thus we have found it a very important agent in hemoptysis of limited severity. In such cases we have added it to specific medicine ergot and furnished it to the patient to keep on hand as an emergency remedy. By having the medicine promptly at hand the patient becomes less agitated or frightened, and this contributes largely to the success of the treatment. Rest and absolute mental composure on the part of the patient and the administration of cinnamon have been promptly effective. If not equal to the emergency, then a small hypodermatic injection of morphine and atropine sulphates will usually check the bleeding. When used with ergot in pulmonary hemorrhage probably more relief comes from the cinnamon than from the ergot, for ergot alone is far less effective. We are told that ergot does not act as well in pulmonary bleeding as in other forms of hemorrhage because of the sparse musculature and poor vaso-motor control of the pulmonic vessels. But cinnamon has given results which have been entirely satisfactory. Hemorrhages from the stomach, bowels, and renal organs are often promptly checked by the timely administration of cinnamon.1


References

1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.