Advance

What kind of medical care would you want if you were too ill or hurt to express your wishes? Advance directives are legal documents that allow you to spell out your decisions about end-of-life care ahead of time. They give you a way to tell your wishes to family, friends, and health care professionals and to avoid confusion later on.

A living will tells which treatments you want if you are dying or permanently unconscious. You can accept or refuse medical care. You might want to include instructions on:

The use of dialysis and breathing machines
If you want to be resuscitated if your breathing or heartbeat stops
Tube feeding
Organ or tissue donation

A durable power of attorney for health care is a document that names your health care proxy. Your proxy is someone you trust to make health decisions for you if you are unable to do so.

NIH: National Cancer Institute

Advance FDA Approved Drugs

AFINITOR [Everolimus^{C₅₃H₈₃NO₁₄}]

10mg (oral tablet)

2.5mg (oral tablet)

7.5mg (oral tablet)

Novartis^{Mar 30, 2009}

Treatment of advanced hormone receptor positive, her2-negative breast cancer in combination with exemestane after failure of treatment with letrozole or anastrozole.
Treatment of patients with progessive neuroendocrine tumors of pancreatic origin (pnet) that are unresectable, locally advanced or metastatic.
Treatment of patients with tuberous sclerosis complex (tsc) who have subependymal giant cell astrocytoma (sega) that requires therapeutic intervention but cannot be curatively resected..
Treatment of solid excretory system tumors; advanced renal cell carcinoma (rcc), after failure of treatment with sunitinib or sorafenib.

efficacy
2.0 (2)

side effects
0.0 (0)

danger
0.0 (0)

FASLODEX [Fulvestrant^{C₃₂H₄₇F₅O₃S}]

50mg/ml (intramuscular injectable)

Astrazeneca^{Apr 25, 2002}

Treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following antiestrogen therapy.
Treatment of hr-positive, human epidermal growth factor receptor 2 (her2)-negative advanced or metastatic breast cancer in combination with palbococlib in women with disease progression after endocrine therapy.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

FIRMAGON [Degarelix Acetate^{C₈₂H₁₀₃ClN₁₈O₁₆C₂H₄O₂H₂O}]

eq 120mg base/vial (subcutaneous powder)

eq 80mg base/vial (subcutaneous powder)

Ferring^{Dec 24, 2008}

Gnrh antagonist indicated for treatment of patients with advanced prostate cancer.
Method of treating prostate cancer.
Treatment of advanced prostate cancer with a reduced likelihood of causing a gonadotrophin releasing hormone agonist side-effect.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

GILOTRIF [Afatinib Dimaleate^{C₂₄H₂₅ClFN₅O₃2C₄H₄O₄}]

eq 20mg base (oral tablet)

eq 30mg base (oral tablet)

eq 40mg base (oral tablet)

Boehringer Ingelheim^{Jul 12, 2013}

Treatment of cancer.
Treatment of patients with advanced (metastatic) non-small cell lung cancer whose disease progressed during or after platinum-based chemotherapy.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

IBRANCE [Palbociclib^{C₂₄H₂₉N₇O₂}]

100mg (oral capsule)

125mg (oral capsule)

75mg (oral capsule)

Pfizer Inc^{Feb 3, 2015}

Treating hr-pos., her2-neg. advanced or metastatic breast cancer with palbociclib in combo with an aromatase inhibitor as initial endocrine based therapy in postmenopausal women or fulvestrant in women with disease progression after endocrine therapy.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

KISQALI [Ribociclib Succinate^{C₂₃H₃₀N₈OC₄H₆O₄}]

eq 200mg base (oral tablet)

Novartis Pharms Corp^{Mar 13, 2017}

In combination with an aromatase inhibitor as initial endocrine-based therapy for treatment of postmenopausal women with hormone receptor (hr)-positive, human epidermal growth factor receptor 2 (her-2)-negative advanced or metastatic breast cancer.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

KISQALI FEMARA CO-PACK (COPACKAGED) [Letrozole^{C₁₇H₁₁N₅} : Ribociclib Succinate^{C₂₃H₃₀N₈OC₄H₆O₄}]

2.5mg,n/a : n/a,eq 200mg base (oral tablet, tablet)

Novartis Pharms Corp^{May 4, 2017}

In combination with an aromatase inhibitor as initial endocrine-based therapy for treatment of postmenopausal women with hormone receptor (hr)-positive, human epidermal growth factor receptor 2 (her-2)-negative advanced or metastatic breast cancer.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

NEXAVAR [Sorafenib Tosylate^{C₂₁H₁₆ClF₃N₄O₃C₇H₈O₃S}]

eq 200mg base (oral tablet)

Bayer Hlthcare^{Dec 20, 2005}

Treatment of advanced renal cell carcinoma.
Treatment of carcinoma of the thyroid.
Treatment of unresectable hepatocellular carcinoma, advanced renal cell carcinoma, or differentiated thyroid carcinoma..
Treatment of unresectable hepatocellular carcinoma.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

SUTENT [Sunitinib Malate^{C₂₂H₂₇FN₄O₂C₄H₆O₅}]

eq 12.5mg base (oral capsule)

eq 25mg base (oral capsule)

eq 37.5mg base (oral capsule)

eq 50mg base (oral capsule)

Cppi Cv^{Jan 26, 2006}

Treatment of gastrointestinal stromal tumor with sunitinib.
Treatment of protein kinase related disorders, such as gastrointestinal stromal tumors, renal cell carcinoma and advanced pancreatic neuroendocrine tumors, with sunitinib.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

TARCEVA [Erlotinib Hydrochloride^{C₂₂H₂₃N₃O₄ClH}]

eq 100mg base (oral tablet)

eq 150mg base (oral tablet)

eq 25mg base (oral tablet)

Osi Pharms^{Nov 18, 2004}

First-line treatment of locally advanced unresectable or metastatic pancreatic cancer, in combination with gemcitabine.
First-line treatment of metastatic non smal-cell lung cancer (nsclc) with egfr exon 19 deletions or exon 21 (l858r) substitution mutations as detected by an fda-approved test.
Maintenance treatment in patients with locally advanced or metastatic nsclc who have not progressed on 1st-line treatment wth platinum-based chemotherapy.
Maintenance treatment of patients with locally advanced or metastatic nsclc whose disease has not progressed after four cycles platinum-based chemotherapy.
Treatment of locally advanced or metastatic non small-cell lung cancer (nsclc) after failure of at least one prior chemotherapy regimen.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

TYKERB [Lapatinib Ditosylate^{C₂₉H₂₆ClFN₄O₄S2C₇H₈O₃SH₂O}]

eq 250mg base (oral tablet)

Novartis Pharms Corp^{Mar 13, 2007}

Treatment of patients with advanced or metastatic breast cancer whose tumors overexpress her2 and who have received prior therapy including anthracycline, a taxane and trastuzumab.
Treatment of patients with breast cancer whose tumors overexpress the her2 receptor.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.

WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Felter's Materia Medica on Advance

ARNICA MONTANA
...f Arnica. Locally. Specific Indications.Muscular soreness and pain from strain or overexertion; advanced stage of disease, with marked enfeeblement, weak circulation, and impaired spinal innervati...... almost all conditions in which prevails the triad-torpor, debility, and depressed function. In the advanced stages of exhausting diseases, where spinal innervation is poor, control over the sphincter...¹

ASPIDOSPERMA
The dried bark of Aspidosperma Quebracho-blanco, Schlechtendal (Nat. Ord. Apocynaceae). An evergreen tree of Chili and the Argentine Republic.... / ...cardiac and renal asthma, emphysema, the dyspnoea of capillary bronchitis and of chronic pneumonia, advanced bronchitis, phthisis, bronchial asthma and uncomplicated asthma with insufficient cardiac f...¹

COCA^ERYTH5
The dried leaves of Erythroxylon Coca, Lamarck, and its varieties. (Nat. Ord. Erythroxylaceae.) South American Andes-Peru, Bolivia, and Chili.... / ...l be for very temporary exhibition in the debility following fevers, or for a more prolonged use in advanced phthisis, to give rest, quiet gastric irritability, and aid breathing. For all prolonged st...¹

EUCALYPTUS^EUAN12
The leaves of Eucalyptus Globulus, Labillardiere. Collected from the older parts of the tree. (Nat. Ord. Myrtaceae.) A native tree of Australia;... / ...the acute exanthemata. If acute desquamative nephritis is present it should not be employed; in the advanced stage of chronic nephritis with very marked fetor in the urine, and scanty secretion of uri... / ...Used according to indications as given above, eucalyptus is a very satisfactory and pleasant medicine. It is best given in syrup or glycerin.¹

LYCOPUS^LYSH2
The whole herb Lycopus virginicus, Linné (Nat. Ord. Labiatae). Common in shady, moist and boggy places throughout the United States. Dose, 1 to... / ... is the most direct indication for lycopus. For this purpose especially it is greatly valued in the advanced stages of acute diseases with great debility, and in chronic diseases with frequent pulse. ... / ...in simple diarrhea (lientery), dysenteric diarrhea, and especially in the diarrhea of phthisis, and the gastric disturbances of the drunkard.¹

References

1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.

Ledgend of Medicine

MODERN MEDICINES

HOME REMEDIES

RANDOM DRUGS

RANDOM AILMENTS

Advance

Advance FDA Approved Drugs

Felter's Materia Medica on Advance

References