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What is a stroke?

A stroke happens when there is a loss of blood flow to part of the brain. Your brain cells cannot get the oxygen and nutrients they need from blood, and they start to die within a few minutes. This can cause lasting brain damage, long-term disability, or even death.

If you think that you or someone else is having a stroke, call 911 right away. Immediate treatment may save someone's life and increase the chances for successful rehabilitation and recovery.

What are the types of stroke?

There are two types of stroke:

  • Ischemic stroke is caused by a blood clot that blocks or plugs a blood vessel in the brain. This is the most common type; about 80% of strokes are ischemic.
  • Hemorrhagic stroke is caused by a blood vessel that breaks and bleeds into the brain

Another condition that's similar to a stroke is a transient ischemic attack (TIA). It's sometimes called a "mini-stroke." TIAs happen when the blood supply to the brain is blocked for a short time. The damage to the brain cells isn't permanent, but if you have had a TIA, you are at a much higher risk of having a stroke.

Who is at risk for a stroke?

Certain factors can raise your risk of a stroke. The major risk factors include:

  • High blood pressure. This is the primary risk factor for a stroke.
  • Diabetes.
  • Heart diseases.Atrial fibrillation and other heart diseases can cause blood clots that lead to stroke.
  • Smoking. When you smoke, you damage your blood vessels and raise your blood pressure.
  • A personal or family history of stroke or TIA.
  • Age. Your risk of stroke increases as you get older.
  • Race and ethnicity. African Americans have a higher risk of stroke.

There are also other factors that are linked to a higher risk of stroke, such as:

  • Alcohol and illegal drug use
  • Not getting enough physical activity
  • High cholesterol
  • Unhealthy diet
  • Having obesity
What are the symptoms of stroke?

The symptoms of stroke often happen quickly. They include:

  • Sudden numbness or weakness of the face, arm, or leg (especially on one side of the body)
  • Sudden confusion, trouble speaking, or understanding speech
  • Sudden trouble seeing in one or both eyes
  • Sudden difficulty walking, dizziness, loss of balance or coordination
  • Sudden severe headache with no known cause

If you think that you or someone else is having a stroke, call 911 right away.

How are strokes diagnosed?

To make a diagnosis, your health care provider will:

  • Ask about your symptoms and medical history
  • Do a physical exam, including a check of
    • Your mental alertness
    • Your coordination and balance
    • Any numbness or weakness in your face, arms, and legs
    • Any trouble speaking and seeing clearly
  • Run some tests, which may include
    • Diagnostic imaging of the brain, such as a CT scan or MRI
    • Heart tests, which can help detect heart problems or blood clots that may have led to a stroke. Possible tests include an electrocardiogram (EKG) and an echocardiography.
What are the treatments for stroke?

Treatments for stroke include medicines, surgery, and rehabilitation. Which treatments you get depend on the type of stroke and the stage of treatment. The different stages are:

  • Acute treatment, to try to stop a stroke while it is happening
  • Post-stroke rehabilitation, to overcome the disabilities caused by the stroke
  • Prevention, to prevent a first stroke or, if you have already had one, prevent another stroke

Acute treatments for ischemic stroke are usually medicines:

  • You may get tPA, (tissue plasminogen activator), a medicine to dissolve the blood clot. You can only get this medicine within 4 hours of when your symptoms started. The sooner you can get it, the better your chance of recovery.
  • If you cannot get that medicine, you may get medicine that helps stop platelets from clumping together to form blood clots. Or you may get a blood thinner to keep existing clots from getting bigger.
  • If you have carotid artery disease, you may also need a procedure to open your blocked carotid artery

Acute treatments for hemorrhagic stroke focus on stopping the bleeding. The first step is to find the cause of bleeding in the brain. The next step is to control it:

  • If high blood pressure is the cause of bleeding, you may be given blood pressure medicines.
  • If an aneurysm if the cause, you may need aneurysm clipping or coil embolization. These are surgeries to prevent further leaking of blood from the aneurysm. It also can help prevent the aneurysm from bursting again.
  • If an arteriovenous malformation (AVM) is the cause of a stroke, you may need an AVM repair. An AVM is a tangle of faulty arteries and veins that can rupture within the brain. An AVM repair may be done through
    • Surgery
    • Injecting a substance into the blood vessels of the AVM to block blood flow
    • Radiation to shrink the blood vessels of the AVM

Stroke rehabilitation can help you relearn skills you lost because of the damage. The goal is to help you become as independent as possible and to have the best possible quality of life.

Prevention of another stroke is also important, since having a stroke increases the risk of getting another one. Prevention may include heart-healthy lifestyle changes and medicines.

Can strokes be prevented?

If you have already had a stroke or are at risk of having a stroke, you can make some heart-healthy lifestyle changes to try to prevent a future stroke:

  • Eating a heart-healthy diet
  • Aiming for a healthy weight
  • Managing stress
  • Getting regular physical activity
  • Quitting smoking
  • Managing your blood pressure and cholesterol levels

If these changes aren't enough, you may need medicine to control your risk factors.

NIH: National Institute of Neurological Disorders and Stroke

Another FDA Approved Drugs

ESBRIET [PirfenidoneC12H11NO]
RX
-
267mg (oral tablet)
801mg (oral tablet)
Genentech IncJan 11, 2017
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.


WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Felter's Materia Medica on Another

ARISÆMA TRIPHYLLUM
   The fresh corm of Arisaema triphyllum, Torre (Nat. Ord. Araceae). Common in damp woods and wet situations in North and South merica. Common Names:... / ...tuents.—Starch, potassium and calcium salts, particularly raphides of calcium oxalate and possibly another acid principle. Preparation.— Tinctura Arisæmæ, Tincture of Arisaema (Corm, 8 ounces; Dil... / ...may be given in drop doses every half to one hour, and a throat wash of one drachm of the tincture to a half glass of water may be used freely. 1

GRANATUM
   The dried bark of the stems and roots of Punica Granatum, Linné (Nat. Ord. Punicaceae). India, southwestern Asia, and the Mediterranean... / ...d in the morning by a saline purge, and then the combined alkaloids administered. In about one hour another dose of the purgative should be given. Epsom salt, fluidextract of jalap, or castor oil may ...1

HEPATICAHEPAT
   The leaves of Hepatica nobilis var. acuta (Anemone acutiloba) (Pursh) Steyermark, and of Hepatica nobilis var. obtusa (A. hepatica) (Pursh)... / ...nergetic agents, seemingly indicated, would aggravate. It came into use under mistaken identity for another plant and acquired a great reputation for virtues it did not possess. The infusion may be gi...1

LIMON
   The juice and outer rind of the fresh ripe fruit of Citrus medica Limonum (Risso), Hooker filius (Nat. Ord. Rutaceae). Northern India, and... / .... Keep the bottle in an upright position. This, while slightly bitter, will keep for several weeks. Another method is to add 10 per cent of brandy to the strained juice. Dose, 1/2 to 4 fluidounces. 2.... / ...of large quantities of acidulated fluid. It also sometimes relieves sick headache, and a hot lemonade is a popular remedy to break up a “cold”.1

OLEUM TEREBINTHINAE RECTIFICATUM
   ...y a flannel cloth wrung from hot water and upon which has been sprinkled a few drops of turpentine. Another but more complicated procedure of preparing a “turpentine stupe” is to wring a flannel ou......ases to drip. Then dip the cloth in turpentine which has been heated in a tin container immersed in another vessel of very hot water and wring out all excess of the oil. (Caution: Turpentine must not ...1

RUBUSRUPA8
   The bark of the root of Rubus villosus, Aiton; Rubus canadensis, Linné; and Rubus trivialis, Michaux (Nat. Ord. Rosaceae). Wild and cultivated in... / ... no appetite, and there is marked pallor of the skin. The syrup or a spiced cordial of the bark and another of the fruit have been used largely in domestic practice to control intractable diarrheas. T...1

STAPHISAGRIA
   The ripe seeds of Delphinium Staphisagria, Linné (Nat. Ord. Ranunculaceae). Mediterranean Basin; cultivated. Dose, 1 to 2 grains. Common Name:... / ...by paralyzing the respiratory centers (asphyxia). One of its alkaloids has narcotic properties; and another, delphinine (dose 1/60 to 1/10 grain), has an acrid and benumbing taste and an action much l... / ...The indications for staphisagria, as concisely stated by us in the American Dispensatory, are given here under Specific Indications.1


WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Physician's Therapeutics Memoranda on Another

LOCOMOTOR ATAXIA
   If due to syphilitic infection antisyphilitic remedies such as potassium iodide and Donovan’s solution. If resulting from metal lic poisoning, iodides to promote elimination. Systematic exercises toregain faculty of coordinating movements. For relief of “lightning” pains, acetanilid, antipyrin, phenacetin, lactophenin, chang ing often from one to another of these and combining them with caffeine; cannabis indica. Solution Gold and Arsenic Bromide, N., B. & Co. may do good.2


References

1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.