Breast
Most women experience breast changes at some time. Your age, hormone levels, and medicines you take may cause lumps, bumps, and discharges (fluids that are not breast milk).
If you have a breast lump, pain, discharge or skin irritation, see your health care provider. Minor and serious breast problems have similar symptoms. Although many women fear cancer, most breast problems are not cancer.
Some common breast changes are:
- Fibrocystic breast changes - lumpiness, thickening and swelling, often just before a woman's period
- Cysts - fluid-filled lumps
- Fibroadenomas - solid, round, rubbery lumps that move easily when pushed, occurring most in younger women
- Intraductal papillomas - growths similar to warts near the nipple
- Blocked milk ducts
- Milk production when a woman is not breastfeeding
NIH: National Cancer Institute
Breast FDA Approved Drugs
ABRAXANE [PaclitaxelC47H51NO14]
RX
- 100mg/vial (iv (infusion) for suspension)
Abraxis BioscienceJan 7, 2005
- Treatment of breast cancer.
- Treatment of lung cancer.
- Treatment of pancreatic cancer.
AFINITOR [EverolimusC53H83NO14]
RX
- 10mg (oral tablet)
2.5mg (oral tablet)
7.5mg (oral tablet)
NovartisMar 30, 2009
- Treatment of advanced hormone receptor positive, her2-negative breast cancer in combination with exemestane after failure of treatment with letrozole or anastrozole.
- Treatment of patients with progessive neuroendocrine tumors of pancreatic origin (pnet) that are unresectable, locally advanced or metastatic.
- Treatment of patients with tuberous sclerosis complex (tsc) who have subependymal giant cell astrocytoma (sega) that requires therapeutic intervention but cannot be curatively resected..
- Treatment of solid excretory system tumors; advanced renal cell carcinoma (rcc), after failure of treatment with sunitinib or sorafenib.
EVISTA [Raloxifene HydrochlorideC28H27NO4SClH]
RX
- 60mg (oral tablet)
LillyDec 9, 1997
- Prevention of osteoporosis in postmenopausal women.
- Use for prevention of breast cancer.
FASLODEX [FulvestrantC32H47F5O3S]
RX
- 50mg/ml (intramuscular injectable)
AstrazenecaApr 25, 2002
- Treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following antiestrogen therapy.
- Treatment of hr-positive, human epidermal growth factor receptor 2 (her2)-negative advanced or metastatic breast cancer in combination with palbococlib in women with disease progression after endocrine therapy.
HALAVEN [Eribulin MesylateC40H59NO11CH4O3S]
RX
- 1mg/2ml (0.5mg/ml) (intravenous solution)
Eisai IncNov 15, 2010
- Treatment of patients with metastatic breast cancer.
- Treatment of patients with unresectable or metastatic liposarcoma.
IBRANCE [PalbociclibC24H29N7O2]
RX
- 100mg (oral capsule)
125mg (oral capsule)
75mg (oral capsule)
Pfizer IncFeb 3, 2015
- Treating hr-pos., her2-neg. advanced or metastatic breast cancer with palbociclib in combo with an aromatase inhibitor as initial endocrine based therapy in postmenopausal women or fulvestrant in women with disease progression after endocrine therapy.
IXEMPRA KIT [IxabepiloneC27H42N2O5S]
RX
- 15mg/vial (iv (infusion) injectable)
45mg/vial (iv (infusion) injectable)
R-pharm Us LlcOct 16, 2007
- A method of treating cancer in a patient comprising administering ixabepilone or pharmaceutical compositions comprising ixabepilone.
- Method of treating breast cancer by administering ixabepilone; a method of treating a cancer responsible to microtubule stabilization by administering ixabepilone.
- Method of treating cancer in a patient comprising intravenously administering to the patient ixabepilone diluted in a parenteral diluent.
- Method of treating cancer, iv admin, lyophylized ixabepilone diluted, every week or 3 weeks; lyophilized ixabepilone with solvent(dehydrated ethanol) diluted to concentration of 0.1mg/ml to 0.9mg/ml.
- Method of treating patient comprising mixing first and second vials of product comprising lyophilized ixabepilone to provide an epothilone analog solution, diluting solution with a suitable diluent to prepare intravenous formulation for pt.
- Use of ixabepilone in combination with capecitabine in treatment of metastasis breast cancer.
KISQALI [Ribociclib SuccinateC23H30N8OC4H6O4]
RX
- eq 200mg base (oral tablet)
Novartis Pharms CorpMar 13, 2017
- In combination with an aromatase inhibitor as initial endocrine-based therapy for treatment of postmenopausal women with hormone receptor (hr)-positive, human epidermal growth factor receptor 2 (her-2)-negative advanced or metastatic breast cancer.
KISQALI FEMARA CO-PACK (COPACKAGED) [LetrozoleC17H11N5 : Ribociclib SuccinateC23H30N8OC4H6O4]
RX
- 2.5mg,n/a : n/a,eq 200mg base (oral tablet, tablet)
Novartis Pharms CorpMay 4, 2017
- In combination with an aromatase inhibitor as initial endocrine-based therapy for treatment of postmenopausal women with hormone receptor (hr)-positive, human epidermal growth factor receptor 2 (her-2)-negative advanced or metastatic breast cancer.
TYKERB [Lapatinib DitosylateC29H26ClFN4O4S2C7H8O3SH2O]
RX
- eq 250mg base (oral tablet)
Novartis Pharms CorpMar 13, 2007
- Treatment of patients with advanced or metastatic breast cancer whose tumors overexpress her2 and who have received prior therapy including anthracycline, a taxane and trastuzumab.
- Treatment of patients with breast cancer whose tumors overexpress the her2 receptor.
WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.
Felter's Materia Medica on Breast
CONIUM
...ous. There is no evidence of it having been of any service in dissipating ulcerating growths of the breast; therefore it is safe to assume that such nodules as are influenced by conium are probably no...... a long course of conium medication with uncertain prospects of relief in undoubted scirrhus of the breast. It may, however, be applied and be given to relieve pain even when a cure is not possible. I...1
...ous. There is no evidence of it having been of any service in dissipating ulcerating growths of the breast; therefore it is safe to assume that such nodules as are influenced by conium are probably no...... a long course of conium medication with uncertain prospects of relief in undoubted scirrhus of the breast. It may, however, be applied and be given to relieve pain even when a cure is not possible. I...1
MATRICARIA
The dried flower-heads of Matricaria Chamomilla, Linné (Nat. Ord. Compositae). Wastes of Europe, Asia, and Australia. Dose, 1 to 60... / ...he matricaria will enhance the efficacy of the latter. Matricaria is useful for the swelling of the breasts in the newborn (usually with phytolacca), and in the involuntary passage of urine in the you... / ...to the actual pain suffered. This remedy should be resorted to when one is tempted to employ opiates and other more powerful pain relievers.1
The dried flower-heads of Matricaria Chamomilla, Linné (Nat. Ord. Compositae). Wastes of Europe, Asia, and Australia. Dose, 1 to 60... / ...he matricaria will enhance the efficacy of the latter. Matricaria is useful for the swelling of the breasts in the newborn (usually with phytolacca), and in the involuntary passage of urine in the you... / ...to the actual pain suffered. This remedy should be resorted to when one is tempted to employ opiates and other more powerful pain relievers.1
SERENOASEREN
The fruit of Serenoa serrulata, Bentham and Hooker (Nat. Ord. Palmacae). Atlantic Coast from Florida to South Carolina. Dose, 10 to 60... / ...ctive organs when undergoing waste of tissue; in some nutritional way it is asserted to enlarge the breasts, ovaries, and testicles, while the paradoxical claim is also made that it reduces hypertroph... / ...orchialgia, and epididymitis. Its best action is that of a nutritive tonic to wasting organs and to control irritation and mucoid discharge.1
The fruit of Serenoa serrulata, Bentham and Hooker (Nat. Ord. Palmacae). Atlantic Coast from Florida to South Carolina. Dose, 10 to 60... / ...ctive organs when undergoing waste of tissue; in some nutritional way it is asserted to enlarge the breasts, ovaries, and testicles, while the paradoxical claim is also made that it reduces hypertroph... / ...orchialgia, and epididymitis. Its best action is that of a nutritive tonic to wasting organs and to control irritation and mucoid discharge.1
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.
Physician's Therapeutics Memoranda on Breast
NIPPLES. FISSURED
Solution of boric acid, 20 grs. to fl. oz., applied to nipple after nursing; glycerite of tannin; silver nitrate carefully applied; solu tion of cocaine, (4 grs. to fl. oz.) just before nursing when very painful (to be carefully washed off, of course, before the child is put to the breast); ichthyol ointment; cacao butter.2
Solution of boric acid, 20 grs. to fl. oz., applied to nipple after nursing; glycerite of tannin; silver nitrate carefully applied; solu tion of cocaine, (4 grs. to fl. oz.) just before nursing when very painful (to be carefully washed off, of course, before the child is put to the breast); ichthyol ointment; cacao butter.2
References
1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.