Breast

What are breast diseases?

Breast diseases include various conditions and changes in your breast. Most women experience breast changes at some time. Your age, hormone levels, and medicines you take may cause lumps, bumps, and discharges of fluids that are not breast milk.

Although many women fear cancer, most breast changes are benign, meaning they are not cancer. These breast changes are known as benign breast disease. See your health care provider if you have a breast lump, pain, discharge, or skin irritation. Minor and serious breast problems often have similar symptoms and may need treatment.

Common breast changes and conditions can include:

Fibrocystic breast changes can include lumpiness, thickening, and swelling, often just before your period. Your breasts may feel painful, swollen, or tender.
Cysts are fluid-filled lumps that may be tender.
Fibroadenomas are solid, round, rubbery lumps that easily move when pushed, occurring most in younger women.
Intraductal papillomas are wart-like benign tumors that grow in the milk duct of the breast.
Blocked milk ducts.
Milk production when you're not breastfeeding.

What are the symptoms of breast disease?

Symptoms depend on the type of breast disease. Benign breast diseases may not have any symptoms, or they could include:

A lump or firm feeling in your breast or under your arm
A change in the size or shape of your breast
Nipple discharge
Skin changes such as itching, redness or darkening, dimples, scaling, or puckering on your breast or nipple
Painful, swollen, or tender breasts

See your provider if you're noticing any of these symptoms or other unusual changes. Some symptoms may be warning signs or symptoms of breast cancer.

How are breast diseases diagnosed?

Some breast changes may be felt or seen. You may notice a change in your breast, or your provider may notice it during a clinical breast exam. Other breast changes may only be found during a screening mammogram or other imaging tests such as an MRI or ultrasound. Your provider may also recommend a breast biopsy to check a suspicious change in your breast.

What are the treatments for breast disease?

Some benign breast changes may increase your risk of breast cancer in the future and may need treatment now. Treatment depends on the type of breast disease that you have. Some breast changes may go away without treatment, while others may require monitoring, biopsy, or surgery.

NIH: National Cancer Institute

Breast FDA Approved Drugs

ABRAXANE [Paclitaxel^{C₄₇H₅₁NO₁₄}]

100mg/vial (iv (infusion) for suspension)

Abraxis Bioscience^{Jan 7, 2005}

Treatment of breast cancer.
Treatment of lung cancer.
Treatment of pancreatic cancer.

efficacy
2.5 (2)

side effects
2.0 (1)

danger
0.0 (0)

AFINITOR [Everolimus^{C₅₃H₈₃NO₁₄}]

10mg (oral tablet)

2.5mg (oral tablet)

7.5mg (oral tablet)

Novartis^{Mar 30, 2009}

Treatment of advanced hormone receptor positive, her2-negative breast cancer in combination with exemestane after failure of treatment with letrozole or anastrozole.
Treatment of patients with progessive neuroendocrine tumors of pancreatic origin (pnet) that are unresectable, locally advanced or metastatic.
Treatment of patients with tuberous sclerosis complex (tsc) who have subependymal giant cell astrocytoma (sega) that requires therapeutic intervention but cannot be curatively resected..
Treatment of solid excretory system tumors; advanced renal cell carcinoma (rcc), after failure of treatment with sunitinib or sorafenib.

efficacy
2.0 (2)

side effects
0.0 (0)

danger
0.0 (0)

EVISTA [Raloxifene Hydrochloride^{C₂₈H₂₇NO₄SClH}]

60mg (oral tablet)

Lilly^{Dec 9, 1997}

Prevention of osteoporosis in postmenopausal women.
Use for prevention of breast cancer.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

FASLODEX [Fulvestrant^{C₃₂H₄₇F₅O₃S}]

50mg/ml (intramuscular injectable)

Astrazeneca^{Apr 25, 2002}

Treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following antiestrogen therapy.
Treatment of hr-positive, human epidermal growth factor receptor 2 (her2)-negative advanced or metastatic breast cancer in combination with palbococlib in women with disease progression after endocrine therapy.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

HALAVEN [Eribulin Mesylate^{C₄₀H₅₉NO₁₁CH₄O₃S}]

1mg/2ml (0.5mg/ml) (intravenous solution)

Eisai Inc^{Nov 15, 2010}

Treatment of patients with metastatic breast cancer.
Treatment of patients with unresectable or metastatic liposarcoma.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

IBRANCE [Palbociclib^{C₂₄H₂₉N₇O₂}]

100mg (oral capsule)

125mg (oral capsule)

75mg (oral capsule)

Pfizer Inc^{Feb 3, 2015}

Treating hr-pos., her2-neg. advanced or metastatic breast cancer with palbociclib in combo with an aromatase inhibitor as initial endocrine based therapy in postmenopausal women or fulvestrant in women with disease progression after endocrine therapy.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

IXEMPRA KIT [Ixabepilone^{C₂₇H₄₂N₂O₅S}]

15mg/vial (iv (infusion) injectable)

45mg/vial (iv (infusion) injectable)

R-pharm Us Llc^{Oct 16, 2007}

A method of treating cancer in a patient comprising administering ixabepilone or pharmaceutical compositions comprising ixabepilone.
Method of treating breast cancer by administering ixabepilone; a method of treating a cancer responsible to microtubule stabilization by administering ixabepilone.
Method of treating cancer in a patient comprising intravenously administering to the patient ixabepilone diluted in a parenteral diluent.
Method of treating cancer, iv admin, lyophylized ixabepilone diluted, every week or 3 weeks; lyophilized ixabepilone with solvent(dehydrated ethanol) diluted to concentration of 0.1mg/ml to 0.9mg/ml.
Method of treating patient comprising mixing first and second vials of product comprising lyophilized ixabepilone to provide an epothilone analog solution, diluting solution with a suitable diluent to prepare intravenous formulation for pt.
Use of ixabepilone in combination with capecitabine in treatment of metastasis breast cancer.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

KISQALI [Ribociclib Succinate^{C₂₃H₃₀N₈OC₄H₆O₄}]

eq 200mg base (oral tablet)

Novartis Pharms Corp^{Mar 13, 2017}

In combination with an aromatase inhibitor as initial endocrine-based therapy for treatment of postmenopausal women with hormone receptor (hr)-positive, human epidermal growth factor receptor 2 (her-2)-negative advanced or metastatic breast cancer.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

KISQALI FEMARA CO-PACK (COPACKAGED) [Letrozole^{C₁₇H₁₁N₅} : Ribociclib Succinate^{C₂₃H₃₀N₈OC₄H₆O₄}]

2.5mg,n/a : n/a,eq 200mg base (oral tablet, tablet)

Novartis Pharms Corp^{May 4, 2017}

In combination with an aromatase inhibitor as initial endocrine-based therapy for treatment of postmenopausal women with hormone receptor (hr)-positive, human epidermal growth factor receptor 2 (her-2)-negative advanced or metastatic breast cancer.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

TYKERB [Lapatinib Ditosylate^{C₂₉H₂₆ClFN₄O₄S2C₇H₈O₃SH₂O}]

eq 250mg base (oral tablet)

Novartis Pharms Corp^{Mar 13, 2007}

Treatment of patients with advanced or metastatic breast cancer whose tumors overexpress her2 and who have received prior therapy including anthracycline, a taxane and trastuzumab.
Treatment of patients with breast cancer whose tumors overexpress the her2 receptor.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.

WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Felter's Materia Medica on Breast

CONIUM
...ous. There is no evidence of it having been of any service in dissipating ulcerating growths of the breast; therefore it is safe to assume that such nodules as are influenced by conium are probably no...... a long course of conium medication with uncertain prospects of relief in undoubted scirrhus of the breast. It may, however, be applied and be given to relieve pain even when a cure is not possible. I...¹

MATRICARIA
The dried flower-heads of Matricaria Chamomilla, Linné (Nat. Ord. Compositae). Wastes of Europe, Asia, and Australia. Dose, 1 to 60... / ...he matricaria will enhance the efficacy of the latter. Matricaria is useful for the swelling of the breasts in the newborn (usually with phytolacca), and in the involuntary passage of urine in the you... / ...to the actual pain suffered. This remedy should be resorted to when one is tempted to employ opiates and other more powerful pain relievers.¹

SERENOA^SEREN
The fruit of Serenoa serrulata, Bentham and Hooker (Nat. Ord. Palmacae). Atlantic Coast from Florida to South Carolina. Dose, 10 to 60... / ...ctive organs when undergoing waste of tissue; in some nutritional way it is asserted to enlarge the breasts, ovaries, and testicles, while the paradoxical claim is also made that it reduces hypertroph... / ...orchialgia, and epididymitis. Its best action is that of a nutritive tonic to wasting organs and to control irritation and mucoid discharge.¹

Physician's Therapeutics Memoranda on Breast

NIPPLES. FISSURED
Solution of boric acid, 20 grs. to fl. oz., applied to nipple after nursing; glycerite of tannin; silver nitrate carefully applied; solu tion of cocaine, (4 grs. to fl. oz.) just before nursing when very painful (to be carefully washed off, of course, before the child is put to the breast); ichthyol ointment; cacao butter.²

References

1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.

Ledgend of Medicine

MODERN MEDICINES

HOME REMEDIES

RANDOM DRUGS

RANDOM AILMENTS

Breast

Breast FDA Approved Drugs

Felter's Materia Medica on Breast

Physician's Therapeutics Memoranda on Breast

References