Cardiac
What is heart disease?
Heart disease is a general term that includes many types of heart problems. It's a type of cardiovascular disease, which means heart and blood vessel disease.
Heart disease is the leading cause of death in the United States, but there are ways to prevent and manage many types of heart disease.
What are the types of heart disease?There are many different types of heart disease. Some you may be born with, called congenital heart disease. Other types develop during your lifetime.
Coronary artery disease (also called coronary heart disease) is the most common type of heart disease. It happens slowly over time when a sticky substance called plaque builds up in the arteries that supply your heart muscle with blood. The plaque narrows or blocks blood flow to the heart muscle and can lead to other heart problems:
- Angina - chest pain from lack of blood flow
- Heart attacks - when part of the heart muscle dies from loss of blood flow
- Heart failure - when your heart can't pump enough blood to meet your body's needs
- Arrhythmia - a problem with the rate or rhythm of your heartbeat
Other types of heart diseases may affect your heart valves or heart muscle (cardiomyopathy).
What causes heart diseases?The causes of heart disease depend on the type of disease. Some possible causes include lifestyle, genetics, infections, medicines, and other diseases.
Who is more likely to develop heart diseases?There are many different factors that can make you more likely to develop heart disease. Some of these factors you can change, but others you cannot.
- Age. Your risk of heart disease goes up as you get older.
- Sex. Some factors may affect heart disease risk differently in women than in men.
- Family history and genetics. A family history of early heart disease raises your risk. And research has shown that some genes are linked to a higher risk of certain heart diseases.
- Race/ethnicity. Heart disease is the leading cause of death in most racial and ethnic groups in the United States. However, certain groups have higher risks than others. This includes Black people, White people, and American Indian/Alaska Native people.
- Lifestyle habits. Over time, unhealthy lifestyle habits can raise your risk of heart disease. These can include:
- Eating a diet high in saturated fats, refined carbohydrates, and salt.
- Not getting enough physical activity.
- Drinking too much alcohol.
- Smoking and exposure to secondhand smoke.
- Too much stress.
- Having other medical conditions can raise your risk of heart diseases. These conditions include:
- High blood pressure.
- High cholesterol levels.
- Diabetes.
- Obesity.
- Autoimmune and inflammatory diseases.
- Chronic kidney disease.
- Metabolic syndrome.
Your symptoms will depend on the type of heart disease you have. You may not have symptoms at first. In some cases, you may not know you have heart disease until you have a complication such as a heart attack.
How are heart diseases diagnosed?To find out if you have heart disease, your health care provider will:
- Ask about your medical history, including your symptoms
- Ask about your family health history, including relatives who have had heart disease
- Do a physical exam
- Likely run heart tests and blood tests
In some cases, your provider may refer you to a cardiologist (a doctor who specializes in heart diseases) for tests, diagnosis, and care.
What are the treatments for heart disease?Treatment plans for heart disease depend on the type of heart disease you have, how serious your symptoms are, and what other health conditions you have. Possible treatments may include:
- Heart-healthy lifestyle changes
- Medicines
- Procedures or surgeries
- Cardiac rehabilitation
You may be able to lower your risk of certain heart diseases by making heart-healthy lifestyle changes and managing any other medical conditions you have.
NIH: National Heart, Lung, and Blood Institute
Cardiac FDA Approved Drugs
- Treatment of conditions for which an aldosterone receptor blocker is indicated, such as hypertension, heart failure, and post-myocardial infarction.
- Treatment of conditions related to hyperaldosteronism such as hypertension and cardiac insufficiency, with eplerenone.
- Treatment of hypertension.
- Use of eplerenone in combination with an angiotensin converting enzyme (ace) inhibitor (and optionally a diuretic) for treating congestive heart failure and hypertension.
- Use of eplerenone in combination with an angiotensin converting enzyme (ace) inhibitor for treating hypertension.
- Reduction of cardiac tissue damage associated with myocardial infarction.
- Treatment or prevention of stroke.
- Emergency treatment of adult & pediatric patients following fluorouracil or capecitabine overdose,or who exhibit early-onset,severe or life-threatening cardiac or cns toxicity or unusually severe adverse reactions within 96 hours.
Felter's Materia Medica on Cardiac
   ...ucosides. Preparation.Specific Medicine Adonis. Dose, 1/2 to 3 drops. Specific Indications.Weak cardiac action, with low blood pressure, and shortened diastole, with consequent venous stasis, with......consequent venous stasis, with increased back-pressure, and feeble intermittent or irregular pulse; cardiac dropsy, with weak heart. Action.Fresh adonis is irritant and vesicant. Upon the circulatio......me reason it is undesirable to employ them. It is especially commended where arryrthmia with feeble cardiac force and dyspnoea and dropsy are present. It has long been a popular remedy in Russia for d...1
   ...ion.Apocynum acts powerfully upon the heart, slowing its action and raising arterial tension. The cardiac muscle appears to be directly stimulated by it as are probably the arterial coats. Contracti......n that diuresis was one of its most prominent results, the knowledge that this is due to the better cardiac pressure and arterial tonus, rather than to the increased intrinsic secreting power of the r...1
   The root of Asclepias incarnata, Linné (Nat. Ord. Asclepiadaceae). Common in damp and wet grounds throughout the United States. Dose, 1 to 60... / ...believe this agent a good diuretic to be substituted for digitalis in cases of edema dependent upon cardiac insufficiency. Its action is similar to that of foxglove, without the irritating effects upo...1
   ...e, anxious and livid; lips cyanotic; pulse small, soft and compressible, irregular or intermittent; cardiac palpitation with cough. Action.The various alkaloids of quebracho act more or less antagon......o pronounced organic changes. Being a centric stimulant to the pneumogastric it affects chiefly the cardiac and pulmonary plexuses, and is a remedy of power in imperfect oxygenation with a disturbed b......ith a disturbed balance between the pulmonic circulation and the action of the heart. It is used in cardiac and renal asthma, emphysema, the dyspnoea of capillary bronchitis and of chronic pneumonia, ...1
   The unripe seed of the Avena sativa, Linné, and the farina derived from the ripened seed (Nat. Ord. Graminaceae). Probably indigenous to Sicily... / ...1/2 to 2 fluidrachms. Specific Indications.Nervous exhaustion; nervous debility of convalescence; cardiac weakness of nervous depression; nocturnal losses following fevers and from the nervous ereth... / ...off the habit has not been sustained. In our own experience we have utterly failed to accomplish any good with it in any form of drug habit. 1
   ...o 10 drops. Specific Indications.Impaired heart action, whether feeble, irregular, or tumultuous; cardiac disorders with mental depression, praecordial oppression, and apprehension of danger and dea......n.Cactus impresses the sympathetic nervous system, and is especially active in its power over the cardiac plexus. In sufficiently large doses it acts as an intense irritant to the cardiac ganglia, p......eart, and even carditis and pericarditis. According to E. M. Hale, M.D., it acts. upon the circular cardiac fibers, whereas digitalis acts upon all the muscular fibers of the heart. Like the latter, a...1
   The unexpanded flowers (dried flower-buds) of Eugenia aromatica (Linné), O Kuntze. (Jambosa Caryophyllus (Sprengel) Niedenzu). (Nat. Ord.... / ...ten relieves nausea and vomiting, gastric pain, and flatulent distention of stomach or bowels. When cardiac palpitation and pain depend upon gastric distention, oil of clove frequently relieves it. Eu...1
   The dried, peeled pulp of the fruit of Citrullus Colocynthis (Linné,) Schrader. (Nat. Ord. Cucurbitaceae.) Mediterranean basin of Europe, Asia,... / ...minute doses give excellent results. When gaseous accumulations cause disturbances of breathing, or cardiac palpitation, with loud belching and expulsion of flatus, and nausea and vomiting are present... / ...of the fifth nerve, when the characteristic cutting pain prevails. It should be given also when colicky pain precedes or accompanies amenorrhoea.1
   ...principle. Preparation.Specific Medicine Convallaria. Dose, 1 to 10 drops. Specific Indications.Cardiac irregularities due to mechanical impediments; mitral insufficiency; feeble circulation and l......echanical impediments; mitral insufficiency; feeble circulation and low arterial tension; dropsy of cardiac origin; palpitation and vehement heart action, with arrythmic movements, dyspnea, and dimini......bly due to capillary resistance or peripheral circulatory enfeeblement. By relieving the latter the cardiac embarrassment is removed. Convallaria slows the pulse and gives increased force to the heart...1
   ...5 to 60 drops. Specific Indications.Tentatively the indications for crataegus may be stated thus: Cardiac weakness, with valvular murmurs, sighing respiration, or other difficult breathing, especial......ssociated with nerve depression or neurasthenia; mitral regurgitation, with valvular insufficiency; cardiac pain; praecordial oppression; dyspnea; rapid and feeble heart action; marked anemia, associ......ession; dyspnea; rapid and feeble heart action; marked anemia, associated with heart irregularity; cardiac hypertrophy; and heartstrain, due to over-exertion or accompanying nervous explosions. Actio...1
   ...accid pulse; weak heart sounds; dusky countenance, with dyspnoea, cough, jugular fullness, and weak cardiac action; edema, anasarca, or ascites with scanty supply of dark-colored urine, with weak hear......apidly but feebly by slight excitement; continuous labored breathing with weak pulsation; renal and cardiac dropsy; desquamative nephritis, with weak heart; capillary hemorrhage; poisoning by aconite,......ted in animals; apparently they do not take place in man. Therapeutic doses, however, stimulate the cardiac inhibitory and vasomotor centers of the medulla. Digitalis, in moderate doses, has little or...1
   The whole plant Euphorbia pilulifera (Chamaesyce hirta), Linné (Nat. Ord. Euphorbiaceae). A plant of tropical climes and throughout the gulf states... / ...hs of the chronic bronchitis of old persons and consumptives. It is also said to relieve dyspnea of cardiac origin and to be of some use in emphysema. It may be administered in syrup, if desired.1
   The root of Helleborus niger, Linné (Nat. Ord. Ranunculaceae.) Subalpine woods of central and southern Europe. Dose, 1 to 10 grains. Common... / ...anity, but is no longer employed for such a purpose. In minute doses it may be employed to increase cardiac power and arterial tension and slow rapid action of the heart. It increases renal activity a...1
   The root of (1) Cephaelis Ipecacuanha (Brotero), A. Richard, or of (2) Cephaelis acuminata, Karsten (Nat. Ord. Rubiaceae). Brazil and other parts... / ...apy as special sedation resulting. Emetine has produced death by gastro-intestinal inflammation and cardiac paralysis. Therapy.The field of therapeutic activity of ipecac is restricted chiefly to th... / ...sight of as a remedy for active hemorrhage. Of course, it operates best where the quantity of blood lost is small. We have seen most excellent r1
   ... rheumatic pains; aching pain in the back; pain upon movement of the eyeballs; excited circulation; cardiac palpitation reflex from gastro-intestinal irritation; chronic syphilitic cachexia. Action an......t is said to allay fever and inflammation, and it is credited with power to relieve symptoms due to cardiac hypertrophy. It is also a remedy for aching pain, shifting rheumatic pain, aching pain in th...1
Physician's Materia Medica on Cardiac
   The tuber, also the leaves (unoflicial) of ACONITU M NAPELLUs, Lin. Actively poisonous. A powerful cardiac depressant acting thus as an arterial sedative; paralyzes sensory nerves and depresses respiratory centers. Used chiefly for its antipyretic effect and in treatment of neuralgia, rheumatism and cardiac hypertrophy; local ly, in liniments, for relief of pain. Dose, 0.015 to 0.12 Grm. (% to 2 grs.).2
   The herb of ADONIS VERNALIS, Lin. Cardiac tonic and diure tic, resembling in its action Digitalis but not liable to produce cumu lative effects. Uses the same as those of Digitalis. Dose, according to Botkin, 0.2 to 0.6 Grm. (3 to 10 grs.), but smaller doses, e. g. 0.06 to 0.12 Grm. (1 to 2 grs.). are commonly given. The active principle is the glucoside adonidin, of which the dose is stated to be 0.004 to 0.016 Grm. (1 16 to % gr.), but this seems large.2
   The stimulant most often used and perhaps also most often mis used. The indication for its use is depressed cardiac action, whether due to shock or to lowered vitality. Alcoholic drinks, vinous or malt ed, serve a good purpose also in some cases in promoting appetite and aiding digestion, but they cannot be prescribed indiscriminately for these effects. As active stimulants whiskey or brandy are most e lcient; gin may be prescribed when a diuretic action is desired; brandy in small doses may rel2
   The rhizome and root of VERATRUM VIRIDE, Solander. Cardiac - depressant. having remarkable power to reduce the pulse in fever. Its most- important use is in controlling blood pressure in aortic an eurism, in cerebral hyperemia and in certain heart affections. Apt to cause nausea unless combined with an opiate. Produces best ef fects when doses are frequently repeated. Dose 0.06 to 0.2 Grm. (1 to 3 grs-).2
   An active cardiac and general stimulant; antacid. Valuable in adynamic fevers, in capillary bronchitis and in some forms of dyspep sia. Dose, as expectorant, 0.13 to 0.20 Grm. (2 to 3 grs.); as stimulant 0.3 to0.6 Grm. (5 to 10 grs.), repeated every hour.2
   Cardiac stimulant, increasing blood pressure and slowing and rendering steady the pulse. Dose, 0.03 to 0.06 Grm. (% to 1 gr.).2
   The tops of CvTIsUs ScormuUs, (L.) Link. Diuretic, laxative. in large doses emeto-cathartic. A valuable remedy in dropsies of cardiac origin and in palpitation of the heart due to weakness of the muscular structure or to valvular disease. Active constituent Spar teine, q. v.2
   The herb LYcoPUs VIRGINICUs, Lin. Antispasmodic and mildly astringent. arterial sedative. Used in pulmonary hemorrhages. in chronic bronchitis and in cardiac affections, relieving palpitat on of the heart. 2
   Alkaloid found in Coffee, Tea, Guarana. Kola and some other plants. Cerebral and cardiac stimulant, acting indirectly as a diure tic. Prescribed often for headache. especially in combination with acetanilid. Useful in adynamic conditions and in all forms of heart failure; a standard remedy in poisoning by opium and other narcotics. Dose of Caffeine or Caffeine Hydrobromide, 0.03 to 0.3 Grm. (96 to 5 grs.- or more. [Caffeine Citrated must be given in double the dose to produce the same effect].2
   The seed of ASAGRAEA OFFICINALIS, (C. & S.) Lindl. Emeto. cathartic, cardiac sedative, but chiefly used externally as a parasiticide. Active principle Veratrine, q. v.2
Physician's Therapeutics Memoranda on Cardiac
   In intervals between attacks, prescribe a simple but nourishing diet with avoidance of all forms of... / In intervals between attacks, prescribe a simple but nourishing diet with avoidance of all forms of excitement or violent exertion; cardiac tonics, arsenic or as an alterative phosphorus. During at tack, amyl nitrite by inhalation, nitroglycerin in solution or hypoder matically; fo...2
   For immediate relief, the smoke from mixtures of stramonium or henbane leaves with nitre and a... / ...all hygienic conditions are favorable. For general treatment, tonics, especially strychnine; grindelia, euphorbia pilulifera; iodides, arsenic; if of cardiac origin, heart tonics, Elixir Digitalin Compound, N., B. & Co.; if arising from gastric irrita tion, trea cause. In any case consider question ...2
   In the early stage, control heart’s action with aconite or veratrum viride; calomel and opium or morphine; leeches or ice bag over pre cordium. Later sustain heart’s action with digitalis. If of rheuma tic or syphilitic origin adopt appropriate general treatment. In cases of acute articular rheumatism, watch for indications of cardiac inflammation and meet symptoms promptly.2
   The remedies commonly resorted to include; 1st cardiac or ar terial sedatives, particularly aconite, 2d antipyretics causing reduc tion of... / The remedies commonly resorted to include; 1st cardiac or ar terial sedatives, particularly aconite, 2d antipyretics causing reduc tion of temperature, to be used always with due caution and wholly... / ...classes of remedies must be suited to the individual case, bearing in mind the fact that fever is not in and of itself necessarily an evil thing.2
   ... is needed; nitroglycerin to diminish arterial tension, aconite when the heart’s action is excessive. Functional disturbance of the heart calls for cardiac tonics when it arises from weakness, aconite in the rarer cases where the heart has been over developed by severe exercise that has been dis c......vere exercise that has been dis continued. Where palpitation arises from debility, general tonics are indicated, particularly nux vomica and iron. In cardiac failure, use diffusible stimulants, ammonia, ether and alcohol.2
   Acute attacks call for aconite as a cardiac sedative with one of the following antiarthritic agents; salicylic acid (best in form of sodium, strontium or... / Acute attacks call for aconite as a cardiac sedative with one of the following antiarthritic agents; salicylic acid (best in form of sodium, strontium or methyl salicylate and accompaine... / ...the most useful remedies internally are potassium iodide, colchicum and cod liver oil. Locally, stimulating liniments are to be applied with friction.2
References
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.