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What is type 2 diabetes?

Type 2 diabetes is a disease in which your blood glucose, or blood sugar, levels are too high. Glucose is your main source of energy. It comes from the foods you eat. A hormone called insulin helps the glucose get into your cells to give them energy. If you have diabetes, your body doesn't make enough insulin or doesn't use insulin well. The glucose then stays in your blood and not enough goes into your cells.

Over time, having too much glucose in your blood can cause health problems. But you can take steps to manage your diabetes and try to prevent these health problems.

What causes type 2 diabetes?

Type 2 diabetes may be caused by a combination of factors:

  • Being overweight or having obesity
  • Not being physically active
  • Genetics and family history

Type 2 diabetes usually starts with insulin resistance. This is a condition in which your cells don't respond normally to insulin. As a result, your body needs more insulin to help the glucose enter your cells. At first, your body makes more insulin to try to get cells to respond. But over time, your body can't make enough insulin, and your blood glucose levels rise.

Who is at risk for type 2 diabetes?

You are at higher risk of developing type 2 diabetes if you:

  • Are over age 45. Children, teenagers, and younger adults can get type 2 diabetes, but it is more common in middle-aged and older people.
  • Have prediabetes, which means that your blood sugar is higher than normal but not high enough to be called diabetes
  • Had diabetes in pregnancy or gave birth to a baby weighing 9 pounds or more.
  • Have a family history of diabetes
  • Are overweight or have obesity
  • Are Black or African American, Hispanic/Latino, American Indian, Asian American, or Pacific Islander
  • Are not physically active
  • Have other conditions such as high blood pressure, heart disease, stroke, polycystic ovary syndrome (PCOS), or depression
  • Have low HDL (good) cholesterol and high triglycerides
  • Have acanthosis nigricans - dark, thick, and velvety skin around your neck or armpits
What are the symptoms of type 2 diabetes?

Many people with type 2 diabetes have no symptoms at all. If you do have them, the symptoms develop slowly over several years. They might be so mild that you do not notice them. The symptoms can include:

  • Increased thirst and urination
  • Increased hunger
  • Feeling tired
  • Blurred vision
  • Numbness or tingling in the feet or hands
  • Sores that do not heal
  • Unexplained weight loss
How is type 2 diabetes diagnosed?

Your health care provider will use blood tests to diagnose type 2 diabetes. The blood tests include:

  • A1C test, which measures your average blood sugar level over the past 3 months
  • Fasting plasma glucose (FPG) test, which measures your current blood sugar level. You need to fast (not eat or drink anything except water) for at least 8 hours before the test.
  • Random plasma glucose (RPG) test, which measures your current blood sugar level. This test is used when you have diabetes symptoms and the provider does not want to wait for you to fast before having the test.
What are the treatments for type 2 diabetes?

Treatment for type 2 diabetes involves managing your blood sugar levels. Many people are able to do this by living a healthy lifestyle. Some people may also need to take medicine.:

  • A healthy lifestyle includes following a healthy eating plan and getting regular physical activity. You need to learn how to balance what you eat and drink with physical activity and diabetes medicine, if you take any.
  • Medicines for diabetes include oral medicines, insulin, and other injectable medicines. Over time, some people will need to take more than one type of medicine to control their diabetes.
  • You will need to check your blood sugar regularly. Your health care provider will tell you how often you need to do it.
  • It's also important to keep your blood pressure and cholesterol levels close to the targets your provider sets for you. Make sure to get your screening tests regularly.
Can type 2 diabetes be prevented?

You can take steps to help prevent or delay type 2 diabetes by losing weight if you are overweight, eating fewer calories, and being more physically active. If you have a condition which raises your risk for type 2 diabetes, managing that condition may lower your risk of getting type 2 diabetes.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Current FDA Approved Drugs

DENAVIR [PenciclovirC10H15N5O3]
RX
-
1% (topical cream)
Mylan Pharms IncSep 24, 1996
  • Treatment of recurrent herpes labialis (cold sores) in adults.
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

ELIQUIS [ApixabanC25H25N5O4]
RX
-
2.5mg (oral tablet)
Bristol Myers SquibbDec 28, 2012
  • Prophylaxis of deep vein thrombosis (dvt).
  • Prophylaxis of deep vein thrombosis and pulmonary embolism.
  • Prophylaxis of pulmonary embolism.
  • Reduce the risk of recurrent deep vein thrombosis (dvt).
  • Reduce the risk of recurrent pulmonary embolism.
  • Reducing the risk of stroke and systemic embolism.
  • Reducing the risk of stroke.
  • Treatment of deep vein thrombosis (dvt).
  • Treatment of pulmonary embolism (pe).
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

NIASPAN [NiacinC6H5NO2]
RX
-
1gm (oral tablet, extended release)
500mg (oral tablet, extended release)
750mg (oral tablet, extended release)
AbbvieJul 28, 1997
  • A method of reducing the capacity of extended release nicotinic acid to provoke a flushing reaction by pretreating an individual with a flush inhibiting agent prior to the administration of the extended release nicotinic acid.
  • Method of treating hyperlipidemia with nicotinic acid by dosing once per day in the evening or at night.
  • Reduction in elevated tc and ldl-c by dosing once per day in the evening or at night, with pretreatment with a flush inhibitin agent such as aspirin.
  • Reduction in elevated tc and ldl-c by dosing once per day in the evening or at night.
  • Reduction in risk of recurrent nonfatal myocardial infarction by dosing once per day in the evening or a t night, with pretreatment with a flush inhibitin agent such as aspirin.
  • Reduction in risk of recurrent nonfatal myocardial infarction by dosing once per day in the evening or at night.
  • Reduction in tg by dosing once per day in the evening or at night, with pretreatment with a flush inhibiting agent such as aspirin.
  • Reduction in tg by dosing once per day in the evening or at night.
  • Treatment of primary and mixed dyslipidemia by dosing once per day in the evening or at night, with pretreatment with a flush inhibiting agent such as aspirin.
  • Treatment of primary and mixed dyslipidemia by dosing once per day in the evening or at night.
efficacy
3.0  (1)
side effects
0.0  (0)
danger
0.0  (0)

UNK

XERESE [AcyclovirC8H11N5O3 : HydrocortisoneC21H30O5]
RX
-
5% : 1% (topical cream)
Valeant BermudaJul 31, 2009
  • Combination product for the early treatment of recurrent herpes labialis (cold sores) to reduce the likelihood of ulcerative cold sores and to shorten the lesion healing time in adults and children (6 years of age and older).
  • New combination product for the early treatment of recurrent herpes labialis (cold sores) to reduce the likelihood of ulcerative cold sores and to shorten the lesion healing time in adults and adolescents (12 years of age and older).
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.


WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Felter's Materia Medica on Current

ALNUS SERRULATA
   The recent bark of Alnus serrulata, Aiton (Nat. Ord. Betulaceae). A shrub of the United States east of the Mississippi River. Common Names: Tag Alder,... / ...nd imperfect peptic function. Its alterative properties are best displayed in pustular eczema and recurrent crops of boils. Passive haematuria is sometimes controlled by its astringent action. 1

ASCLEPIAS TUBEROSA
   The root of Asclepias tuberosa, Linné (Nat. Ord. Asclepiadaceae). United States and Canada. Dose, 5 to 60 grains. Common Names: Pleurisy Root,... / ...ient and in which it first earned a therapeutic reputation. It may need to be fortified by the intercurrent use of aconite or bryonia, or both, and in any case it will enhance the value of these agent...1

BELLADONNA (Atropa belladonna)ATROP
   The (1) dried root and the (2) dried leaves and tops of Atropa Belladonna, Linné (Nat. Ord. Solanaceae). Europe and Central Asia; also... / ...iciency. Thus they may be applied to painful and swollen joints, forming abscesses, incipient and recurrent boils, buboes, hemorrhoids and fissures, inflamed glands, and in neuralgia, chronic rheumati...1

CAPSICUM
   The ripe fruit, dried, of Capsicum frutescens, Linné (Nat. Ord. Solanaceae). Tropical America; also cultivated in most tropical countries. Dose,... / ...inflammation is present. Nevertheless, in low grades of inflammation and fever, with sluggish blood current, it is a most efficient and necessary stimulant when given in small doses. The infusion of c...1

DIGITALIS
   ...a better contraction of the heart-muscle and some constriction of the arterioles, so that the blood-current is reduced in size and the quantity of blood sent out through the systemic arteries is lesse......sels and lessened number of contractions more blood would be propelled into the body. As it is, the current is carried more completely to the extremities of the capillaries, and altogether the circula...1

EUPATORIUM PERFOLIATUM
   The flowering tops and leaves of Eupatorium perfoliatum, Linné (Nat. Ord. Compositae). Swamps and low meadows throughout the United States. Dose,... / ...torii, Infusion of Boneset. Dose, 1 to 4 fluidrachms. Specific Indications .—Large full pulse, the current showing little waves; skin hot and full, with a tendency to become moist, even during the pr... / ...tonic and stomachic, when given in small doses it improves the appetite and digestion and thus favors a more rapid and perfect convalescence.1

GELSEMIUM
   The dried rhizome and roots of Gelsemium sempervirens (Linné,) Aiton (Nat. Ord. Loganiaceae). Dose, 1/10 to 1 grain. Common Names: Yellow... / ...proper doses it relaxes high nervous and muscular tension. By diminishing the velocity of the blood current to the head and spinal tract it prevents spasmodic action. It is, therefore, a remedy for hy... / ...great restlessness and excitation” are the classic indications for it as first formulated by Scudder, and these stand among the truest of speci1

JUNIPERUS COMMUNIS
   The fruit (berries) of the Juniperus communis, Linné (Nat. Ord. Cupressaceae). An evergreen tree of Europe and America. Common Names: Juniper,... / ... there is active inflammation. The infusion is extremely useful in irritation of the bladder with recurrent attacks of distressing pain and frequent urination in women during the menopause and apparen... / ...given in doses larger than recommended above, as suppression of urine, strangury, hematuria, or even uremic convulsions may result from its use.1

LAPPA (Arctium lappa)ARLA3
   ... Specific Indications.—Feeble cutaneous circulation; dry, scaly skin eruptions; aphthous ulcers; recurrent boils and styes; urinary irritation; psoriasis. Action and Therapy.—Lappa is a potent but n...... obstinate ulcers, and in catarrhal and aphthous ulcerations. It is one of the best of agents for recurrent boils and styes. Bronchial cough, with much irritation of the pulmonary tract, is relieved b...1

LOBELIALOBEL
   The leaves, tops, and seeds of Lobelia inflata, Linné (Nat. Ord. Lobeliaceae). Abundant in the United States. Dose, 1 to 60 grains. Common... / ...ullness of tissue, with full veins and full arterial flow; full labored and doughy pulse, the blood current moving with difficulty; short, labored breathing; sense of suffocation; dyspnea with praecor...1

LYCOPUSLYSH2
   The whole herb Lycopus virginicus, Linné (Nat. Ord. Labiatae). Common in shady, moist and boggy places throughout the United States. Dose, 1 to... / ...assive pulmonary hemorrhage (hemoptysis). It probably acts by controlling the rapidity of the blood-current. In the first-named hemorrhages it may also act upon the unstriped muscular fibers, but in t... / ...in simple diarrhea (lientery), dysenteric diarrhea, and especially in the diarrhea of phthisis, and the gastric disturbances of the drunkard.1

MELILOTUS
   The leaves and flowering tops of Melilotus officinalis, Willdenow (Nat. Ord. Leguminosae). A common weed found everywhere in the United States. Dose, 1... / ... the stomach, visceral neuralgia, painful dysuria, and sciatic neuritis. It frequently cuts short recurrent neuralgia when induced by cold, and benefits in rheumatoid lameness or soreness.1

PASSIFLORAPABE10
   The root and stem-base of Passiflora incarnata, Linné (Nat. Ord. Passifloraceae). Southern United States. Dose, 5 to 120 grains. Common Names:... / ... in most varieties of spasm when established, except in epilepsy, it is a far better agent for intercurrent use to control the irritability which precedes and often provokes the convulsive explosions.... / ...frequently proves one of the most effective of remedies.1


WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Physician's Therapeutics Memoranda on Current

TONSILLITIS
   A good routine treatment is; a mercurial followed by a Seidlitz powder, with aconite to control... / ...ly, hot fomentations (the hop poultice is eflicient) or Glyceroplasma. Phenol Camphor may be used external ly with advantage in some cases. In mild recurrent attacks, Ton sillitis tablets (see p. 189) are often efficient. In rheumatic subjects, iodides, sodium salicylate and tincture guaiac should b...2


References

1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.