Phosphate

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a genetic disorder that is most common in males. About 1 in 10 African American males in the United States has it. G6PD deficiency mainly affects red blood cells, which carry oxygen from the lungs to tissues throughout the body. The most common medical problem it can cause is hemolytic anemia. That happens when red blood cells are destroyed faster than the body can replace them.

If you have G6PD deficiency, you may not have symptoms. Symptoms happen if your red blood cells are exposed to certain chemicals in food or medicine, certain bacterial or viral infections, or stress. They may include:

Paleness
Jaundice
Dark urine
Fatigue
Shortness of breath
Enlarged spleen
Rapid heart rate

A blood test can tell if you have it. Treatments include medicines to treat infection, avoiding substances that cause the problem with red blood cells, and sometimes transfusions.

NIH: National Library of Medicine

Phosphate FDA Approved Drugs

ACANYA [Benzoyl Peroxide^{C₁₄H₁₀O₄} : Clindamycin Phosphate^{C₁₈H₃₄ClN₂O₈PS}]

2.5% : eq 1.2% base (topical gel)

Dow Pharm^{Oct 23, 2008}

Topical treatment of acne vulgaris in patients 12 years or older.
Topical treatment of acne vulgaris.
Treatment of acne vulgaris.
Treatment of acne.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

ACETAMINOPHEN AND CODEINE PHOSPHATE [Acetaminophen^{C₈H₉NO₂} : Codeine Phosphate^{2C₁₈H₂₁NO₃H₂O2H₃O₄P}]

120mg/5ml : 12mg/5ml (oral solution)

300mg : 15mg (oral tablet)

300mg : 30mg (oral tablet)

300mg : 60mg (oral tablet)

Hi Tech Pharma^{Apr 26, 1996}
Mikart^{Oct 27, 1992}
Pharm Assoc^{Approved Prior To Jan 1, 1982}
Vintage Pharms^{Nov 10, 2011}
Wockhardt^{Approved Prior To Jan 1, 1982}
Aurolife Pharma Llc^{Apr 15, 2013}
Mallinckrodt Inc^{May 31, 2001}
Teva^{Mar 6, 1985}
Amneal Pharms Ny^{May 29, 2008}
Sun Pharm Inds Ltd^{Approved Prior To Jan 1, 1982}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

AMINOSYN 7% W/ ELECTROLYTES [Amino Acids : Magnesium Chloride^2ClMg6H₂O : Potassium Phosphate, Dibasic : Sodium Chloride^ClNa]

7% : 102mg/100ml : 522mg/100ml : 410mg/100ml (injection injectable)

Icu Medical Inc^{Approved Prior To Jan 1, 1982}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

AMINOSYN 8.5% W/ ELECTROLYTES [Amino Acids : Magnesium Chloride^2ClMg6H₂O : Potassium Phosphate, Dibasic : Sodium Chloride^ClNa]

8.5% : 102mg/100ml : 522mg/100ml : 410mg/100ml (injection injectable)

Icu Medical Inc^{Approved Prior To Jan 1, 1982}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

AMINOSYN II 10% W/ ELECTROLYTES [Amino Acids : Magnesium Chloride^2ClMg6H₂O : Potassium Chloride^ClK : Potassium Phosphate, Dibasic : Sodium Chloride^ClNa]

10% : 102mg/100ml : 45mg/100ml : 522mg/100ml : 410mg/100ml (injection injectable)

Icu Medical Inc^{Apr 3, 1986}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

AMINOSYN II 8.5% W/ ELECTROLYTES [Amino Acids : Magnesium Chloride^2ClMg6H₂O : Potassium Chloride^ClK : Potassium Phosphate, Dibasic : Sodium Chloride^ClNa]

8.5% : 102mg/100ml : 45mg/100ml : 522mg/100ml : 410mg/100ml (injection injectable)

Icu Medical Inc^{Apr 3, 1986}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

ARALEN [Chloroquine Phosphate^{C₁₈H₂₆ClN₃2H₃O₄P}]

eq 300mg base (oral tablet)

Sanofi Aventis Us^{Approved Prior To Jan 1, 1982}

efficacy
2.0 (3)

side effects
1.5 (2)

danger
2.0 (1)

BENZACLIN [Benzoyl Peroxide^{C₁₄H₁₀O₄} : Clindamycin Phosphate^{C₁₈H₃₄ClN₂O₈PS}]

5% : eq 1% base (topical gel)

Valeant Bermuda^{Dec 21, 2000}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

BETAMETHASONE ACETATE AND BETAMETHASONE SODIUM PHOSPHATE [Betamethasone Acetate^{C₂₄H₃₁FO₆} : Betamethasone Sodium Phosphate^{C₂₂H₂₈FO₈P2Na}]

3mg/ml : eq 3mg base/ml (injection injectable)

Luitpold^{Jul 31, 2009}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

BSS PLUS [Calcium Chloride^Ca2Cl2H₂O : Dextrose : Glutathione Disulfide : Magnesium Chloride^2ClMg6H₂O : Potassium Chloride^ClK : Sodium Bicarbonate^CHO₃Na : Sodium Chloride^ClNa : Sodium Phosphate]

0.154mg/ml : 0.92mg/ml : 0.184mg/ml : 0.2mg/ml : 0.38mg/ml : 2.1mg/ml : 7.14mg/ml : 0.42mg/ml (irrigation solution)

Alcon^{Approved Prior To Jan 1, 1982}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE [Acetaminophen^{C₈H₉NO₂} : Butalbital^{C₁₁H₁₆N₂O₃} : Caffeine^{C₈H₁₀N₄O₂} : Codeine Phosphate^{2C₁₈H₂₁NO₃H₂O2H₃O₄P}]

300mg : 50mg : 40mg : 30mg (oral capsule)

325mg : 50mg : 40mg : 30mg (oral capsule)

Nexgen Pharma Inc^{Jul 19, 2012}
Hikma Intl Pharms^{Mar 23, 2001}
Vintage Pharms^{Apr 22, 2002}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

BUTALBITAL, ASPIRIN, CAFFEINE AND CODEINE PHOSPHATE [Aspirin^C₉H₈O₄ : Butalbital^{C₁₁H₁₆N₂O₃} : Caffeine^{C₈H₁₀N₄O₂} : Codeine Phosphate^{2C₁₈H₂₁NO₃H₂O2H₃O₄P}]

325mg : 50mg : 40mg : 30mg (oral capsule)

Mayne Pharma Inc^{Oct 30, 2015}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

BUTALBITAL, ASPIRIN, CAFFEINE, AND CODEINE PHOSPHATE [Aspirin^C₉H₈O₄ : Butalbital^{C₁₁H₁₆N₂O₃} : Caffeine^{C₈H₁₀N₄O₂} : Codeine Phosphate^{2C₁₈H₂₁NO₃H₂O2H₃O₄P}]

325mg : 50mg : 40mg : 30mg (oral capsule)

Nexgen Pharma Inc^{Nov 30, 2001}
Stevens J^{Aug 31, 1998}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

CAPITAL AND CODEINE [Acetaminophen^{C₈H₉NO₂} : Codeine Phosphate^{2C₁₈H₂₁NO₃H₂O2H₃O₄P}]

120mg/5ml : 12mg/5ml (oral suspension)

Valeant Pharms Llc^{Approved Prior To Jan 1, 1982}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

CARISOPRODOL, ASPIRIN AND CODEINE PHOSPHATE [Aspirin^C₉H₈O₄ : Carisoprodol^{C₁₂H₂₄N₂O₄} : Codeine Phosphate^{2C₁₈H₂₁NO₃H₂O2H₃O₄P}]

325mg : 200mg : 16mg (oral tablet)

Ingenus Pharms Nj^{Jan 7, 2010}
Sandoz^{Apr 16, 1996}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

CELESTONE SOLUSPAN [Betamethasone Acetate^{C₂₄H₃₁FO₆} : Betamethasone Sodium Phosphate^{C₂₂H₂₈FO₈P2Na}]

3mg/ml : eq 3mg base/ml (injection injectable)

Merck Sharp Dohme^{Approved Prior To Jan 1, 1982}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

CHLOROQUINE PHOSPHATE [Chloroquine Phosphate^{C₁₈H₂₆ClN₃2H₃O₄P}]

eq 150mg base (oral tablet)

eq 300mg base (oral tablet)

Hikma Pharms Llc^{Approved Prior To Jan 1, 1982}
Ipca Labs Ltd^{Dec 3, 2009}
Natco Pharma Ltd^{Jan 21, 2011}

efficacy
2.0 (2)

side effects
1.0 (1)

CIS-PYRO [Technetium Tc-99m Pyrophosphate Kit]

n/a (injection injectable)

Pharmalucence^{Jun 30, 1987}

CLEOCIN [Clindamycin Phosphate^{C₁₈H₃₄ClN₂O₈PS}]

100mg (vaginal suppository)

eq 1% base (topical swab)

eq 2% base (vaginal cream)

Pharmacia And Upjohn^{Aug 13, 1999}

CLEOCIN PHOSPHATE [Clindamycin Phosphate^{C₁₈H₃₄ClN₂O₈PS}]

eq 150mg base/ml (injection injectable)

Pharmacia And Upjohn^{Approved Prior To Jan 1, 1982}

CLEOCIN PHOSPHATE IN DEXTROSE 5% IN PLASTIC CONTAINER [Clindamycin Phosphate^{C₁₈H₃₄ClN₂O₈PS}]

eq 12mg base/ml (injection injectable)

eq 18mg base/ml (injection injectable)

eq 6mg base/ml (injection injectable)

Pharmacia And Upjohn^{Aug 30, 1989}

CLEOCIN T [Clindamycin Phosphate^{C₁₈H₃₄ClN₂O₈PS}]

eq 1% base (topical solution)

Pharmacia And Upjohn^{Approved Prior To Jan 1, 1982}

CLINDA-DERM [Clindamycin Phosphate^{C₁₈H₃₄ClN₂O₈PS}]

eq 1% base (topical solution)

Paddock Llc^{Sep 30, 1992}

CLINDAGEL [Clindamycin Phosphate^{C₁₈H₃₄ClN₂O₈PS}]

eq 1% base (topical gel)

Precision Dermat^{Nov 27, 2000}

Topical treatment of acne vulgaris.

CLINDAMYCIN PHOSPHATE [Clindamycin Phosphate^{C₁₈H₃₄ClN₂O₈PS}]

1% (topical aerosol, foam)

eq 1% base (topical swab)

eq 150mg base/ml (injection injectable)

eq 2% base (vaginal cream)

Perrigo Uk Finco^{Mar 31, 2010}
Akorn^{Jun 17, 2010}
Fougera Pharms^{Feb 14, 2006}
Fougera Pharms Inc^{Jun 5, 1997}
G And W Labs Inc^{Sep 1, 1988}
Perrigo New York^{May 25, 2000}
Taro Pharm Inds^{Mar 31, 2004}
Teligent Pharma Inc^{Dec 30, 2016}
Vintage Pharms^{May 29, 2015}
Wockhardt^{Jul 15, 1997}
Alvogen Inc^{Jul 24, 1987}
Fresenius Kabi Usa^{Mar 29, 2007}
Sagent Pharms^{Sep 30, 2011}
West-ward Pharms Int^{Apr 25, 1988}

CLINDAMYCIN PHOSPHATE AND BENZOYL PEROXIDE [Benzoyl Peroxide^{C₁₄H₁₀O₄} : Clindamycin Phosphate^{C₁₈H₃₄ClN₂O₈PS}]

2.5% : eq 1.2% base (topical gel)

5% : 1.2% (topical gel)

5% : eq 1% base (topical gel)

Actavis Labs Ut Inc^{Jun 19, 2015}
Perrigo Israel^{Jun 26, 2012}
Tolmar^{Aug 25, 2016}
Mylan Pharms Inc^{Aug 11, 2009}

CLINDAMYCIN PHOSPHATE AND TRETINOIN [Clindamycin Phosphate^{C₁₈H₃₄ClN₂O₈PS} : Tretinoin^{C₂₀H₂₈O₂}]

1.2% : 0.025% (topical gel)

Actavis Mid Atlantic^{Jun 12, 2015}

CLINDAMYCIN PHOSPHATE IN 0.9% SODIUM CHLORIDE [Clindamycin Phosphate^{C₁₈H₃₄ClN₂O₈PS}]

eq 300mg base/50ml (eq 6mg base/ml) (iv (infusion) solution)

eq 600mg base/50ml (eq 12mg base/ml) (iv (infusion) solution)

eq 900mg base/50ml (eq 18mg base/ml) (iv (infusion) solution)

Baxter Hlthcare Corp^{Apr 20, 2017}

CLINDAMYCIN PHOSPHATE IN 5% DEXTROSE IN PLASTIC CONTAINER [Clindamycin Phosphate^{C₁₈H₃₄ClN₂O₈PS}]

eq 12mg base/ml (injection injectable)

eq 18mg base/ml (injection injectable)

eq 6mg base/ml (injection injectable)

Akorn Inc^{Apr 4, 2013}
Celerity Pharms^{Jun 28, 2017}
Sandoz Inc^{May 31, 2012}

CLINDAMYCIN PHOSPHATE IN DEXTROSE 5% [Clindamycin Phosphate^{C₁₈H₃₄ClN₂O₈PS}]

eq 900mg base/100ml (injection injectable)

Abraxis Pharm^{Dec 22, 1989}

WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.

WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Felter's Materia Medica on Phosphate

EUPHORBIA COROLLATA
The bark of the root of Euphorbia corollata, Linné (Nat. Ord. Euphorbiaceae). Dry fields and woods of Canada and the United States. Common Names:... / ...ter, and of this a teaspoonful may be taken every 2 hours. Bowles also used it, with phytolacca and phosphate of hydrastin, to reduce enlarged tonsils following tonsillitis. The American species of Eu... / ...from the pulmonic, gastro-intestinal, or urino-genital mucosa; or the tough, glutinous tracheo-broncho-pulmonic secretions, with irritation.¹

MATRICARIA
The dried flower-heads of Matricaria Chamomilla, Linné (Nat. Ord. Compositae). Wastes of Europe, Asia, and Australia. Dose, 1 to 60... / ...tion, but it is of little value after convulsions occur. Sometimes a gently laxative dose of sodium phosphate preceding or accompanying the matricaria will enhance the efficacy of the latter. Matricar... / ...to the actual pain suffered. This remedy should be resorted to when one is tempted to employ opiates and other more powerful pain relievers.¹

Physician's Materia Medica on Phosphate

BERBERINE (Hydrastin)
Alkaloid from GOLDEN-SEAL and some other related plants. Bit ter tonic, hepatic stimulant, antiperiodic. The Hydrochloride is the salt most used. The sulphate and phosphate have' identical proper ties, and have the advantage of being more soluble. Dose of either, 0.06 to 0.25 Grm. (1 to 4 grs.).²

CASCARA CARMINATIVE
Hepatic stimulant, laxative and intestinal antiseptic. Each fluidrachm represents; Cascara Sagrada, 30 grs.; Blue Flag, 2 grs,; Wahoo. 3 grs.; Sodlum Phosphate, 5 grs.; Sodium Salicylate, 2 grs,; with Aromatics, q. s. Dose, as laxative, 4 c. c. (1 fluidrachm).²

HYDRANGEA^HYDRA
The root of HYDRANGEA ARBORESCENs, Lin. Diuretic. antilithic; in large doses cathartic. Prescribed with good results in renal colic, especially when due to deposits of phosphates.²

PHOSPHATES
Calcium Phosphate plays an important part in the animal econ omy in supplying the principal part of the solid framework of the body. Hence phosphates constitute an essential part of our food. In some diseased conditions the system fails to assimilate from the ordi nary food suflicient of these compounds to supply the daily waste, and in these conditions the deficiency must be made up by the use of chemicalfonds consisting of combinations of the phosphates of cal. cium, sodium, potassium and iron²

SODIUM PHOSPHATE
Laxative and hepatic stimulant, sub-alkaline; prescribed to regulate the bowels in infancy, and as a remedy for morbid conditions dependant on torpidity of the liver. Dose for infants, 0.15 to 0.25 Grm. (2 to 4 grs.) several times a day; for adults as a hepatic stimulant, 1 to 4 Grru. (15 to 60 grs.), as a laxative 4 to 15 Grm. (1 to 4 drachms) or more.²

Physician's Therapeutics Memoranda on Phosphate

AMBLYOPIA
Ascertain the cause. If due to constitutional taint, use altera tives. notably potassium iodide.... / ...trychnine; if from uremia, Tonic Pilocarpine Compound; if from auto-intoxication, a mercurial purge; ii from ex cess, Eupeptic Hypophosphites. glycerophosphates, strychnine and other tonics, with avoidance of cause; ii lrom tobacco or almhol, ab stain lrom these and use heart tonics, especially Elix...²

CALCULI, BILIARY
Relieve pain by hypodermatic injection of morphine and atropine and by cautious inhalations of chloroform, 20 to 30 minims at a... / ...ble, 2nd by exercise, active and passive (horseback riding, massage over hypochondrium), 3rd by medication; sodium salicylate, benzoate, succinate or phosphate, alkaline mineral waters, effervesciug granules Vichy, oil turpentine internally.²

CIRRHOSIS OF LIVER
Remedies especially valuable are; ammonium chloride, potas sium iodide, sodium phosphate, nitro-muriatic acid, Solution Gold and Arsenic Bromide, N., B. & Co.²

CONSTIPATION
Medicate no more than is necessary. Prescribe regular open air exercise, regularity in going to stool; correct the diet; advise a large glass of Apolinaris before... / ...of podophyllin with nux vomica and belladonna; 4, saline waters or their equiva lent in effervescing granules, particularly the preparation of sodium phosphate.²

GASTRIC CATARRH
...e pint Bismuth subnitrate and cerium oxalate are useful. Later regulate diet carefully and prescribe as tonic a mixture containing columbo and sodium phosphate. Be sure that medicines do not irritate the stomach. For pain apply spice poultice or hot water bag. In Chronic Gastric Catarrh, lavage is t...... do not irritate the stomach. For pain apply spice poultice or hot water bag. In Chronic Gastric Catarrh, lavage is the most important remedy. Sodium phosphate in solution or effervescing granules, or ,a saline mineral water; bismuth; antacids and gastric antiseptics as needed; silver nitrate combin...²

HEMORRHOIDS
The bowels must be kept free (best by compound liquorice powder, Fl. Ext. Cascara Sagrada Aromatic, N., B.... / The bowels must be kept free (best by compound liquorice powder, Fl. Ext. Cascara Sagrada Aromatic, N., B. & Co. or solution sodium phosphate); portal congestion if present must be remedied; evacuation of the bowels should be in the evening. The best local applica tions (preferably... / ...Surgical treatment is often required.²

JAUNDICE
Treatment is somewhat empirical, the remedies most used being sodium phosphate (20 to 120 grs. two or three times a day), hydrastis, iodoform, citric acid, pilocarpine and salol. When due to catarrh of the duct, calomel and sodium bicarbonate in divided doses followed by a saline cathartic.²

NEURASTHENIA
The remedies indicated are tonics and poborants; hypophosphites (Eupeptic or Vitalic), glycerophosphates, phosphorus, hematics, arse nic; Solution Gold and Arsenic Bromide, N., B. & Co. Change of oc cupation and scene, exercise in the open air as it can be borne, electricity, are often of more value than medication.²

OBESITY
Regulate the diet, withholding fatty, saccharine and starchy food to a large extent; as remedies, prescribe saline waters, e. g. Kis singen and Vichy on alternate days (the Effervescing Granules are convenient) or sodium phosphate; fluid extract bladder-wrack; ex tract thyroid gland; Turkish baths; suitable exercise, active or passive.²

OSTEO-MALACIA
Phosphorus, especially associated with other reconstructive tonics; glycerophosphates; cod liver oil; syrup ferrous iodide.²

PARALYSIS AGITANS
Useful remedies are combinations of strychnine, arsenic and iron; cannabis ind ica, zinc valerianate and gelsemium; glycerophosphates; sparteine, belladonna.²

RACHITIS
The disease is one of non-assimilation, the remedies, 1st general tonics and nutrients; cod liver oil. quinine, copper arsenite, syrup ferrous iodide, Haemo-Mangan; 2d Bone lood; phosphorus. glycero phosphates, hypophosphites, lacto-phosphates, Eupeptic Hypophos phites, N., B. & Co. Thyroid extract and suprarenal extract have given good results. Improve hygienic condition of patient and prescribe massage and passive exercise when this is practicable.²

References

1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.

Ledgend of Medicine

MODERN MEDICINES

HOME REMEDIES

RANDOM DRUGS

RANDOM AILMENTS

Phosphate

Phosphate FDA Approved Drugs

Felter's Materia Medica on Phosphate

Physician's Materia Medica on Phosphate

Physician's Therapeutics Memoranda on Phosphate

References