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Cleft lip and cleft palate are birth defects that occur when a baby's lip or mouth do not form properly. They happen early during pregnancy. A baby can have a cleft lip, a cleft palate, or both.

A cleft lip happens if the tissue that makes up the lip does not join completely before birth. This causes an opening in the upper lip. The opening can be a small slit or a large opening that goes through the lip into the nose. It can be on one or both sides of the lip or, rarely, in the middle of the lip.

Children with a cleft lip also can have a cleft palate. The roof of the mouth is called the "palate." With a cleft palate, the tissue that makes up the roof of the mouth does not join correctly. Babies may have both the front and back parts of the palate open, or they may have only one part open.

Children with a cleft lip or a cleft palate often have problems with feeding and talking. They also might have ear infections, hearing loss, and problems with their teeth.

Often, surgery can close the lip and palate. Cleft lip surgery is usually done before age 12 months, and cleft palate surgery is done before 18 months. Many children have other complications. They may need additional surgeries, dental and orthodontic care, and speech therapy as they get older. With treatment, most children with clefts do well and lead a healthy life.

Centers for Disease Control and Prevention

Plus FDA Approved Drugs

ACETAMINOPHEN, CAFFEINE AND DIHYDROCODEINE BITARTRATE [Acetaminophen^{C₈H₉NO₂} : Caffeine^{C₈H₁₀N₄O₂} : Dihydrocodeine Bitartrate^{C₁₈H₂₃NO₃C₄H₆O₆}]

325mg : 30mg : 16mg (oral tablet)

Larken Labs Inc^{Sep 30, 2016}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

ACTOPLUS MET [Metformin Hydrochloride^{C₄H₁₁N₅ClH} : Pioglitazone Hydrochloride^{C₁₉H₂₀N₂O₃SClH}]

500mg : eq 15mg base (oral tablet)

850mg : eq 15mg base (oral tablet)

Takeda Pharms Usa^{Aug 29, 2005}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

ACTOPLUS MET XR [Metformin Hydrochloride^{C₄H₁₁N₅ClH} : Pioglitazone Hydrochloride^{C₁₉H₂₀N₂O₃SClH}]

1gm : eq 15mg base (oral tablet, extended release)

1gm : eq 30mg base (oral tablet, extended release)

Takeda Pharms Usa^{May 12, 2009}

Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus who are already treated with pioglitazone and metformin or who have inadequate glycemic control on pioglitazone or metformin alone.
Adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes who are already treated with a pioglitazone and metformin.
To reduce gastrointestinal side effects administer with a meal; as starting dose administer once daily with evening meal.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

BACTRIM [Sulfamethoxazole^{C₁₀H₁₁N₃O₃S} : Trimethoprim^{C₁₄H₁₈N₄O₃}]

400mg : 80mg (oral tablet)

Sun Pharm Inds^{Approved Prior To Jan 1, 1982}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

BACTRIM DS [Sulfamethoxazole^{C₁₀H₁₁N₃O₃S} : Trimethoprim^{C₁₄H₁₈N₄O₃}]

800mg : 160mg (oral tablet)

Sun Pharm Inds^{Approved Prior To Jan 1, 1982}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

BSS PLUS [Calcium Chloride^Ca2Cl2H₂O : Dextrose : Glutathione Disulfide : Magnesium Chloride^2ClMg6H₂O : Potassium Chloride^ClK : Sodium Bicarbonate^CHO₃Na : Sodium Chloride^ClNa : Sodium Phosphate]

0.154mg/ml : 0.92mg/ml : 0.184mg/ml : 0.2mg/ml : 0.38mg/ml : 2.1mg/ml : 7.14mg/ml : 0.42mg/ml (irrigation solution)

Alcon^{Approved Prior To Jan 1, 1982}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

BUTALBITAL, ACETAMINOPHEN AND CAFFEINE [Acetaminophen^{C₈H₉NO₂} : Butalbital^{C₁₁H₁₆N₂O₃} : Caffeine^{C₈H₁₀N₄O₂}]

300mg : 50mg : 40mg (oral capsule)

325mg/15ml : 50mg/15ml : 40mg/15ml (oral solution)

325mg : 50mg : 40mg (oral tablet)

Nexgen Pharma^{Nov 16, 2009}
Nuvo Pharm Inc^{Oct 28, 2016}
Mikart^{Jan 31, 2003}
Actavis Labs Ut Inc^{Nov 9, 1984}
Cnty Line Pharms^{Jan 10, 2017}
Hikma Pharms Llc^{Jun 12, 1995}
Lannett Holdings Inc^{Sep 13, 2012}
Mallinckrodt Inc^{Jan 24, 1985}
Mayne Pharma Inc^{Mar 17, 1986}
Vintage Pharms^{Aug 27, 2003}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

ENDOSOL EXTRA [Calcium Chloride^Ca2Cl2H₂O : Dextrose : Glutathione Disulfide : Magnesium Chloride^2ClMg6H₂O : Potassium Chloride^ClK : Sodium Bicarbonate^CHO₃Na : Sodium Chloride^ClNa : Sodium Phosphate]

0.154mg/ml : 0.92mg/ml : 0.184mg/ml : 0.2mg/ml : 0.38mg/ml : 2.1mg/ml : 7.14mg/ml : 0.42mg/ml (irrigation solution)

Akorn^{Nov 27, 1991}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

ENLON-PLUS [Atropine Sulfate^{2C₁₇H₂₃NO₃H₂OH₂O₄S} : Edrophonium Chloride^{C₁₀H₁₆NOCl}]

0.14mg/ml : 10mg/ml (injection injectable)

Mylan Institutional^{Nov 6, 1991}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

FOSAMAX PLUS D [Alendronate Sodium^{C₄H₁₂NO₇P₂Na3H₂O} : Cholecalciferol^{C₂₇H₄₄O}]

eq 70mg base : 2,800 iu (oral tablet)

eq 70mg base : 5,600 iu (oral tablet)

Merck^{Apr 7, 2005}

Treatment of osteoporosis in post menopausal women and/or the treatment to increase bone mass in men with osteoporosis.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

KYPROLIS [Carfilzomib^{C₄₀H₅₇N₅O₇}]

30mg/vial (intravenous powder)

60mg/vial (intravenous powder)

Onyx Therap^{Jun 3, 2016}

Kyprolis is indicated in combination with lenalidomide plus dexamethasone for the treatment of patients with relapsed or refractory multiple myeloma who have received one to three lines of therapy.
Treatment of patients with multiple myeloma who have received at least two prior therapies including bortezomib and an immunomodulatory agent and have demonstrated disease progression on or within 60 days of completion of the last therapy.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

M.V.I.-12 (WITHOUT VITAMIN K) [Ascorbic Acid^C₆H₈O₆ : Biotin^{C₁₀H₁₆N₂O₃S} : Cyanocobalamin^{C₆₂H₈₈N₁₃O₁₄PCNCo} : Dexpanthenol^{C₉H₁₉NO₄} : Ergocalciferol^{C₂₈H₄₄O} : Folic Acid^{C₁₉H₁₉N₇O₆} : Niacinamide^{C₆H₆N₂O} : Pyridoxine Hydrochloride^{C₈H₁₁NO₃ClH} : Riboflavin 5'-phosphate Sodium^{C₁₇H₂₀N₄O₉PNa2H₂O} : Thiamine Hydrochloride; Vitamin A; Vitamin E]

20mg/ml : 0.006mg/ml : 0.05mcg/ml : 1.5mg/ml : 0.0005mg/ml : 0.06mg/ml : 4mg/ml : 0.6mg/ml : 0.36mg/ml : 0.6mg/ml : 0.1mg/ml : 1mg/ml (injection injectable)

Hospira^{Sep 9, 2004}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

ONGLYZA [Saxagliptin Hydrochloride^{C₁₈H₂₅N₃O₂ClH}]

eq 2.5mg base (oral tablet)

eq 5mg base (oral tablet)

Astrazeneca Ab^{Jul 31, 2009}

Method for treating type ii diabetes by administering saxagliptin.
Method for treating type ii diabetes mellitus by administering saxagliptin alone or in combination with insulin, metformin, a thiazolidinedione, glyburide or metformin plus a sulfonylurea.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

PIOGLITAZONE HYDROCHLORIDE AND METFORMIN HYDROCHLORIDE [Metformin Hydrochloride^{C₄H₁₁N₅ClH} : Pioglitazone Hydrochloride^{C₁₉H₂₀N₂O₃SClH}]

500mg : eq 15mg base (oral tablet)

850mg : eq 15mg base (oral tablet)

Aurobindo Pharma Ltd^{Feb 13, 2013}
Macleods Pharms Ltd^{Nov 5, 2015}
Mylan^{Feb 25, 2011}
Sandoz^{Apr 16, 2013}
Teva Pharms Usa^{Mar 10, 2014}
Torrent Pharms Ltd^{Feb 13, 2013}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

SEPTRA [Sulfamethoxazole^{C₁₀H₁₁N₃O₃S} : Trimethoprim^{C₁₄H₁₈N₄O₃}]

400mg : 80mg (oral tablet)

Monarch Pharms^{Approved Prior To Jan 1, 1982}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

SEPTRA DS [Sulfamethoxazole^{C₁₀H₁₁N₃O₃S} : Trimethoprim^{C₁₄H₁₈N₄O₃}]

800mg : 160mg (oral tablet)

Monarch Pharms^{Approved Prior To Jan 1, 1982}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

SULFAMETHOXAZOLE AND TRIMETHOPRIM [Sulfamethoxazole^{C₁₀H₁₁N₃O₃S} : Trimethoprim^{C₁₄H₁₈N₄O₃}]

200mg/5ml : 40mg/5ml (oral suspension)

400mg : 80mg (oral tablet)

800mg : 160mg (oral tablet)

80mg/ml : 16mg/ml (injection injectable)

Aurobindo Pharma^{Jun 8, 2010}
Hi Tech Pharma^{Dec 29, 1997}
Vintage^{Jan 24, 2007}
Amneal Pharms Ny^{Jan 27, 2005}
Chartwell Molecules^{Jan 25, 2007}
Glenmark Generics^{Dec 22, 2010}
Vista Pharms^{Oct 7, 2005}
Sun Pharm Inds^{Aug 25, 1986}
Teva Pharms Usa^{Oct 31, 1991}

efficacy
0.0 (0)

side effects
0.0 (0)

SULFAMETHOXAZOLE AND TRIMETHOPRIM DOUBLE STRENGTH [Sulfamethoxazole^{C₁₀H₁₁N₃O₃S} : Trimethoprim^{C₁₄H₁₈N₄O₃}]

800mg : 160mg (oral tablet)

Teva^{Jun 2, 1987}

SULFAMETHOXAZOLE AND TRIMETHOPRIM SINGLE STRENGTH [Sulfamethoxazole^{C₁₀H₁₁N₃O₃S} : Trimethoprim^{C₁₄H₁₈N₄O₃}]

400mg : 80mg (oral tablet)

Teva Pharms^{Jun 2, 1987}

SULFATRIM PEDIATRIC [Sulfamethoxazole^{C₁₀H₁₁N₃O₃S} : Trimethoprim^{C₁₄H₁₈N₄O₃}]

200mg/5ml : 40mg/5ml (oral suspension)

Sti Pharma Llc^{Jan 7, 1983}

TREZIX [Acetaminophen^{C₈H₉NO₂} : Caffeine^{C₈H₁₀N₄O₂} : Dihydrocodeine Bitartrate^{C₁₈H₂₃NO₃C₄H₆O₆}]

320.5mg : 30mg : 16mg (oral capsule)

Wraser Pharms Llc^{Nov 26, 2014}

WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.

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Plus FDA Approved Drugs