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Role

What is asthma?

Asthma is a chronic (long-term) lung disease. It affects your airways, the tubes that carry air in and out of your lungs. When you have asthma, your airways can become inflamed and narrowed. This can cause wheezing, coughing, and tightness in your chest. When these symptoms get worse than usual, it is called an asthma attack or flare-up.

What causes asthma?

The exact cause of asthma is unknown. Genetics and your environment likely play a role in who gets asthma.

An asthma attack can happen when you are exposed to an asthma trigger. An asthma trigger is something that can set off or worsen your asthma symptoms. Different triggers can cause different types of asthma:

  • Allergic asthma is caused by allergens. Allergens are substances that cause an allergic reaction. They can include
    • Dust mites
    • Mold
    • Pets
    • Pollen from grass, trees, and weeds
    • Waste from pests such as cockroaches and mice
  • Nonallergic asthma is caused by triggers that are not allergens, such as
    • Breathing in cold air
    • Certain medicines
    • Household chemicals
    • Infections such as colds and the flu
    • Outdoor air pollution
    • Tobacco smoke
  • Occupational asthma is caused by breathing in chemicals or industrial dusts at work
  • Exercise-induced asthma happens during physical exercise, especially when the air is dry

Asthma triggers may be different for each person and can change over time.

Who is at risk for asthma?

Asthma affects people of all ages, but it often starts during childhood. Certain factors can raise your risk of having asthma:

  • Being exposed to secondhand smoke when your mother is pregnant with you or when you are a small child
  • Being exposed to certain substances at work, such as chemical irritants or industrial dusts
  • Genetics and family history. You are more likely to have asthma if one of your parents has it, especially if it's your mother.
  • Race or ethnicity. Black and African Americans and Puerto Ricans are at higher risk of asthma than people of other races or ethnicities.
  • Having other diseases or conditions such as obesity and allergies
  • Often having viral respiratory infections as a young child
  • Sex. In children, asthma is more common in boys. In teens and adults, it is more common in women.
What are the symptoms of asthma?

The symptoms of asthma include:

  • Chest tightness
  • Coughing, especially at night or early morning
  • Shortness of breath
  • Wheezing, which causes a whistling sound when you breathe out

These symptoms can range from mild to severe. You may have them every day or only once in a while.

When you are having an asthma attack, your symptoms get much worse. The attacks may come on gradually or suddenly. Sometimes they can be life-threatening. They are more common in people who have severe asthma. If you are having asthma attacks, you may need a change in your treatment.

How is asthma diagnosed?

Your health care provider may use many tools to diagnose asthma:

  • Physical exam
  • Medical history
  • Lung function tests, including spirometry, to test how well your lungs work
  • Tests to measure how your airways react to specific exposures. During this test, you inhale different concentrations of allergens or medicines that may tighten the muscles in your airways. Spirometry is done before and after the test.
  • Peak expiratory flow (PEF) tests to measure how fast you can blow air out using maximum effort
  • Fractional exhaled nitric oxide (FeNO) tests to measure levels of nitric oxide in your breath when you breathe out. High levels of nitric oxide may mean that your lungs are inflamed.
  • Allergy skin or blood tests, if you have a history of allergies. These tests check which allergens cause a reaction from your immune system.
What are the treatments for asthma?

If you have asthma, you will work with your health care provider to create a treatment plan. The plan will include ways to manage your asthma symptoms and prevent asthma attacks. It will include:

  • Strategies to avoid triggers. For example, if tobacco smoke is a trigger for you, you should not smoke or allow other people to smoke in your home or car.
  • Short-term relief medicines, also called quick-relief medicines. They help prevent symptoms or relieve symptoms during an asthma attack. They include an inhaler to carry with you all the time. It may also include other types of medicines which work quickly to help open your airways.
  • Control medicines. You take them every day to help prevent symptoms. They work by reducing airway inflammation and preventing narrowing of the airways.

If you have a severe attack and the short-term relief medicines do not work, you will need emergency care.

Your provider may adjust your treatment until asthma symptoms are controlled.

Sometimes asthma is severe and cannot be controlled with other treatments. If you are an adult with uncontrolled asthma, in some cases your provider might suggest bronchial thermoplasty. This is a procedure that uses heat to shrink the smooth muscle in the lungs. Shrinking the muscle reduces your airway's ability to tighten and allows you to breathe more easily. The procedure has some risks, so it's important to discuss them with your provider.

Role FDA Approved Drugs

ANTARA (MICRONIZED) [FenofibrateC20H21ClO4]
RX
-
130mg (oral capsule)
43mg (oral capsule)
90mg (oral capsule)
Lupin AtlantisNov 30, 2004
  • Treating hypercholesterolemias with reduction of food effect.
  • Treating hypertriglyceridemias with reduction of food effect.
  • Treating primary hypercholesterolemia and mixed dyslipidemia.
  • Treating severe hypertriglyceridemia.
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

BETAMETHASONE DIPROPIONATE [Betamethasone DipropionateC28H37FO7]
RX
-
eq 0.05% base (topical ointment, augmented)
Actavis Mid AtlanticAug 31, 1995
FougeraSep 4, 1984
Fougera PharmsDec 9, 2003
Fougera Pharms IncAug 12, 1985
G And W Labs IncAug 10, 1987
Glenmark GenericsSep 23, 2008
Perrigo New YorkDec 9, 2003
TaroApr 30, 1992
TolmarJan 23, 2004
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

BROMFENAC SODIUM [Bromfenac Sodium2C15H11BrNO32Na3H2O]
RX
-
eq 0.09% acid (ophthalmic solution/drops)
Amring PharmsJan 9, 2013
Apotex IncJun 19, 2014
Hi-tech PharmacalJan 22, 2014
Paddock LlcFeb 10, 2015
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

BROMSITE [Bromfenac Sodium2C15H11BrNO32Na3H2O]
RX
-
eq 0.075% acid (ophthalmic solution/drops)
Sun Pharma GlobalApr 8, 2016
  • Treatment of postoperative inflammation and prevention of ocular pain in patients undergoing cataract surgery.
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

CRESTOR [Rosuvastatin Calcium2C22H27FN3O6SCa]
RX
-
10mg (oral tablet)
20mg (oral tablet)
40mg (oral tablet)
5mg (oral tablet)
IprAug 12, 2003
  • Treatment of pediatric patients 8 to 17 years of age with heterozygous familial hypercholesterolemia (hefh).
  • Use of rosuvastatin calcium for the primary prevention of cardiovascular disease in individuals without clinically evident coronary heart disease but with increased risk factors.
  • Use of rosuvastatin calcium to reduce elevated total-c, ldl-c, apob, nonhdl-c or tg levels; to increase hdl-c in adult patients with primary hyperlipidemia or mixed dyslipidemia; and to slow the progression of atherosclerosis..
efficacy
4.5  (2)
side effects
1.0  (1)
danger
1.0  (1)

UNK

DANTRIUM [Dantrolene Sodium2C14H9N4O52Na7H2O]
RX
-
100mg (oral capsule)
20mg/vial (injection injectable)
25mg (oral capsule)
50mg (oral capsule)
Par Sterile ProductsApproved Prior To Jan 1, 1982
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

DANTROLENE SODIUM [Dantrolene Sodium2C14H9N4O52Na7H2O]
RX
-
100mg (oral capsule)
20mg/vial (injection injectable)
25mg (oral capsule)
50mg (oral capsule)
Elite Labs IncOct 24, 2005
Impax LabsMar 1, 2005
Hikma Pharms LlcJun 19, 2017
Mylan InstitutionalFeb 18, 2016
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

DIPROLENE [Betamethasone DipropionateC28H37FO7]
RX
-
eq 0.05% base (topical lotion, augmented)
Merck Sharp DohmeAug 1, 1988
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

DIPROLENE AF [Betamethasone DipropionateC28H37FO7]
RX
-
eq 0.05% base (topical cream, augmented)
Merck Sharp DohmeApr 27, 1987
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

EUCRISA [CrisaboroleC14H10BNO3]
RX
-
2% (topical ointment)
Anacor Pharms IncDec 14, 2016
  • Method of treating mild to moderate atopic dermatitis..
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

JUXTAPID [Lomitapide MesylateC39H37F6N3O2CH4O3S]
RX
-
eq 10mg base (oral capsule)
eq 20mg base (oral capsule)
eq 30mg base (oral capsule)
eq 40mg base (oral capsule)
eq 5mg base (oral capsule)
eq 60mg base (oral capsule)
AegerionDec 21, 2012
  • A dosing regimen for the treatment of hypercholesterolemia and hyperlipidemia in patients with homozygous familial hypercholesterolemia using at least three step-wise increasing doses.
  • A dosing regimen for the treatment of hypercholesterolemia and hyperlipidemia in patients with homozygous familial hypercholesterolemia using at least three step-wise increasing doses.
  • Treatment of hypercholesterolemia by decreasing the amount or activity of microsomal triglyceride transfer protein in patients with homozygous familial hypercholesterolemia.
  • Treatment of hypercholesterolemia, hyperlipidemia and hyperlipoproteinemia in patients with homozygous familial hypercholesterolemia.
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

KERYDIN [TavaboroleC7H6BFO2]
RX
-
5% (topical solution)
Anacor Pharms IncJul 7, 2014
  • Treatment for onychomycosis that is tinea unguium.
  • Treatment of onychomychosis of a toenail caused by trichophyton rubrum or trichophyton mentagrophytes.
  • Treatment of onychomycosis of a toenail.
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

KYNAMRO [Mipomersen SodiumC230H305N67O122P19S1919Na]
RX
-
200mg/ml (200mg/ml) (subcutaneous solution)
Kastle Theraps LlcJan 29, 2013
  • Adjunctive therapy to lipid-lowering medications and diet to reduce low density lipoprotein-cholesterol, apolipoprotein b, total cholesterol, and non-high density lipoprotein cholesterol in pts with homozygous familial hypercholesterolemia.
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

PROLENSA [Bromfenac Sodium2C15H11BrNO32Na3H2O]
RX
-
eq 0.07% acid (ophthalmic solution/drops)
Bausch And LombApr 5, 2013
  • Method of treating ocular inflammation.
  • Method of treatment to alleviate inflammation of the eye.
  • Treatment of postoperative inflammation and reduction of ocular pain in patients who have undergone cataract surgery.
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

REQUIP [Ropinirole HydrochlorideC16H24N2OClH]
RX
-
eq 0.25mg base (oral tablet)
eq 0.5mg base (oral tablet)
eq 1mg base (oral tablet)
eq 2mg base (oral tablet)
eq 3mg base (oral tablet)
eq 4mg base (oral tablet)
eq 5mg base (oral tablet)
Glaxosmithkline LlcSep 19, 1997
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

REQUIP XL [Ropinirole HydrochlorideC16H24N2OClH]
RX
-
eq 12mg base (oral tablet, extended release)
eq 2mg base (oral tablet, extended release)
eq 4mg base (oral tablet, extended release)
eq 6mg base (oral tablet, extended release)
eq 8mg base (oral tablet, extended release)
Glaxosmithkline LlcOct 31, 2008
  • A process for treating a patient suffering from parkinson's syndrome and in need of treatment.
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

REVONTO [Dantrolene Sodium2C14H9N4O52Na7H2O]
RX
-
20mg/vial (injection injectable)
Us WorldmedsJul 24, 2007
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

ROPINIROLE HYDROCHLORIDE [Ropinirole HydrochlorideC16H24N2OClH]
RX
-
eq 0.25mg base (oral tablet)
eq 0.5mg base (oral tablet)
eq 12mg base (oral tablet, extended release)
eq 1mg base (oral tablet)
eq 2mg base (oral tablet)
Accord HlthcareFeb 28, 2017
Alembic LtdMar 24, 2010
ApotexFeb 7, 2012
G And W Labs IncMay 5, 2008
Glenmark GenericsFeb 25, 2010
MylanMay 5, 2008
Orchid HlthcareNov 28, 2012
Prinston IncMay 5, 2008
West-ward Pharms IntMay 5, 2008
WockhardtMay 29, 2008
Zydus Pharms Usa IncJun 1, 2009
Actavis ElizabethMay 17, 2012
Alembic Pharms LtdApr 22, 2013
Dr Reddys Labs LtdJun 6, 2012
Mylan Pharms IncOct 15, 2012
Sandoz IncJun 6, 2012
Watson Labs IncJun 6, 2012
Wockhardt LtdAug 27, 2012
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.


WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Felter's Materia Medica on Role

GOSSYPIUM
   The bark of the root and the hairs of the seed of Gossypium herbaceum, LinnĂ©, and of other species of Gossypium (Nat. Ord. Malvaceae). An Asiatic... / ...ss oil, having a bland taste; slightly dissolved by alcohol and miscible with ether, chloroform, petroleum, and benzin. Dose, 1/2 to 2 fluidounces. Specific Indications.-(Uterine inertia; preparations...1


References

1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.