Vascular
What are vascular diseases?
Your vascular system is your body's network of blood vessels. It includes your:
- Arteries, which carry oxygen-rich blood from your heart to your tissues and organs
- Veins, which carry the blood and waste products back to your heart
- Capillaries, which are tiny blood vessels that connect your small arteries to your small veins. The walls of the capillaries are thin and leaky, to allow for an exchange of materials between your tissues and blood.
Vascular diseases are conditions which affect your vascular system. They are common and can be serious. Some types include:
- Aneurysm - a bulge or "ballooning" in the wall of an artery
- Atherosclerosis - a disease in which plaque builds up inside your arteries. Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood.
- Blood clots, including deep vein thrombosis and pulmonary embolism
- Coronary artery disease and carotid artery disease, diseases that involve the narrowing or blockage of an artery. The cause is usually a buildup of plaque.
- Raynaud's disease - a disorder that causes the blood vessels to narrow when you are cold or feeling stressed
- Stroke - a serious condition that happens when blood flow to your brain stops.
- Varicose veins - swollen, twisted veins that you can see just under the skin
- Vasculitis - inflammation of the blood vessels
The causes of vascular diseases depend on the specific disease. These causes include:
- Genetics
- Heart diseases such as high cholesterol and high blood pressure
- Infection
- Injury
- Medicines, including hormones
Sometimes the cause is unknown.
Who is at risk for vascular diseases?The risk factors for vascular diseases can vary, depending on the specific disease. But some of the more common risk factors include:
- Age - your risk of some diseases goes up as you get older
- Conditions that can affect the heart and blood vessels, such as diabetes or high cholesterol
- Family history of vascular or heart diseases
- Infection or injury that damages your veins
- Lack of exercise
- Obesity
- Pregnancy
- Sitting or standing still for long periods of time
- Smoking
The symptoms for each disease are different.
How are vascular diseases diagnosed?To make a diagnosis, your health care provider will do a physical exam and ask about your symptoms and medical history. You may have imaging tests and/or blood tests.
How are vascular diseases treated?Which treatment you get depends on which vascular disease you have and how severe it is. Types of treatments for vascular diseases include:
- Lifestyle changes, such as eating a heart-healthy diet and getting more exercise
- Medicines, such as blood pressure medicines, blood thinners, cholesterol medicines, and clot-dissolving drugs. In some cases, providers use a catheter to send medicine directly to a blood vessel.
- Non-surgical procedures, such as angioplasty, stenting, and vein ablation
- Surgery
There are steps you can take to help prevent vascular diseases:
- Make healthy lifestyle changes, such as eating a heart-healthy diet and getting more exercise
- Don't smoke. If you are already a smoker, talk to your health care provider for help in finding the best way for you to quit.
- Keep your blood pressure and cholesterol in check
- If you have diabetes, control your blood sugar
- Try not to sit or stand for up long periods of time. If you do need to sit all day, get up and move around every hour or so. If you traveling on a long trip, you can also wear compression stockings and regularly stretch your legs.
Vascular FDA Approved Drugs
- Temporary reduction of fever.
- Temporary relief of minor aches and pains.
- Treatment/prevention of cardiovascular disease.
- Method of inhibiting platelet aggregation.
- Reduction of the rate of cardiovascular death, myocardial infarction, and stroke in patients with a history of myocardial infarction.
- Reduction of the rate of cardiovascular death, myocardial infarction, and stroke in patients with acute coronary syndrome or a history of myocardial infarction.
- Reduction of the rate of thrombotic events in patients with acute coronary syndrome.
- Treatment of an arterial thrombotic complication in a patient with coronary artery, cerebrovascular or peripheral vascular disease.
- Treatment of arterial thrombotic complications selected from the group consisting of unstable angina, thrombotic or embolic stroke, transient ischaemic attacks, peripheral vascular disease and myocardial infarction.
- Treatment of myocardial infarction and stroke in patients with acute coronary syndrome or a history of myocardial infarction.
- Treatment of myocardial infarction in patients with acute coronary syndrome or a history of myocardial infarction.
- Treatment of myocardial infarction.
- Treatment of post-myocardial infarction.
- Treatment of stable and unstable angina.
- Treatment of stroke in patients with acute coronary syndrome or a history of myocardial infarction.
- Treatment of stroke.
- Treatment of thrombotic stroke.
- Treatment of pediatric patients 8 to 17 years of age with heterozygous familial hypercholesterolemia (hefh).
- Use of rosuvastatin calcium for the primary prevention of cardiovascular disease in individuals without clinically evident coronary heart disease but with increased risk factors.
- Use of rosuvastatin calcium to reduce elevated total-c, ldl-c, apob, nonhdl-c or tg levels; to increase hdl-c in adult patients with primary hyperlipidemia or mixed dyslipidemia; and to slow the progression of atherosclerosis..
- Administration once daily within two hours after waking in the morning for improvement of glycemic control in a type 2 diabetes patient.
- Improvement of glycemic control in individuals with type 2 diabetes.
- Improvements of glycemic control in individuals with type 2 diabetes who have one or more specified cardiovascular risk factors.
- Treatment of type 2 diabetes by administering bromocriptine mesylate and a first-phase insulin secretagogue wherein the combined therapeutic effect is greater than the additive effect of administering each agent alone.
- Treatment of hypertension.
- Use of valsartan to reduce cardiovascular mortality in clinically stable patients with left ventricular failure or left ventricular dysfunction following myocardial infarction.
- Treatment or prophylaxis of thrombosis or embolisms.
- Use of prasugrel and aspirin in patients requiring the reduction of thrombotic cardiovascular events.
- Method of treating hypertension.
- Treatment of cardiovascular disorders.
- Management of risk of dronedarone/beta-blocker interaction in patients in sinus rythm with a history of paroxysmal or persistent af.
- Reduction in risk of hospitalization in patients with a history of paroxysmal or persistent af without severe heart failure and with one or more risk factors by administration twice a daily with morning and evening meals.
- Reduction in risk of hospitalization in patients with coronary heart disease and a history of paroxysmal or persistent af and with one or more risk factors by administration twice a day with morning and evening meals.
- Reduction in risk of hospitalization in patients with stable nyha class iii heart failure and a history of paroxysmal or persistent af and with one or more risk factors by administration twice a day with morning and evening meals.
- Reduction of the risk of cardiovascular hospitalization.
- Reduction of the risk of hospitalization for atrial fibrillation.
- Treatment of patients with a history of paroxysmal or persistent af without severe heart failure and with one or more risk factors by administration twice a day with morning and evening meals.
- Treatment or secondary prevention of cardiovascular disease, cardiovascular events, or cerebrovascular events and risk-reduction of aspirin-associated gastric ulcers.
- Reduction of thrombotic cardiovascular events.
Home Remedies for Vascular
   Olive Oil contains omega-3 and omega-6 fatty acids. Omega-3 are prostaglandins which increase blood flow, reduce inflammation and the formation of blood clots. Three polyphenolic compounds in olive oil, oleuropein, tyrosol and hydroxytyrosol, along with mono-unsaturated fat, may be responsible for preventing LDL cholesterol from being oxidized and sticking to the inner walls of arteries. This is referred to as plaque, which restricts blood flow.
Mechanism - oleuropein, tyrosol, hydroxytyrosolSleslie | August 27th, 2020
Felter's Materia Medica on Vascular
   The bark and prepared resinous exudate of Tsuga canadensis, Carriére (Abies canadensis, Michaux; Pinus canadensis, Linné). (Nat. Ord.... / ...Oil of Hemlock. Dose, 1 to 5 drops. Specific Indications.General asthenia, with feeble digestion, vascular weakness, and pale and relaxed mucosa; broncho-pulmonic irritation, with profuse secretions... / ...be used where there is excessive secretion of mucus and the cough is largely precipitated by a feeble and relaxed state of the uvula and fauces. 2
   The dried tuberous root of Aconitum Napellus, Linné (Nat. Ord. Ranunculaceae). Mountains of Europe and Asia, and northwestern North America.... / ...mperature and not due to sepsis, is the most direct indication. Irritation of mucous membranes with vascular excitation and determination of blood; hyperemia; chilly sensations; skin hot and dry, with... / ...approaching from the extremities to the body. Excessive sweating comes on, rapidly lowering the body temperature, dimness of vision, 2
   ...dation from the blood vessels is the ideal condition which we seek to remedy with apocynum. It is a vascular stimulant. Such results one would not expect to obtain if there were circulatory obstructio......ca in its results. One can not expect apocynum to reconstruct wornout tissues or to restore damaged vascular valves. We must not hope to work miracles with it where there are such structural lesions a...2
   The dried flower-heads of Arnica montana, Linné (Nat. Ord. Compositae). A perennial of Siberia and the cooler parts of Europe; also found in... / ...al enervation. It should be brought into service when there is deficient nervous response, sluggish vascular power, and in almost all conditions in which prevails the triad-torpor, debility, and depre...2
   ...ndent on motion (Scudder). Skin hot and dry, or inclined to moisture; urine scanty; face flushed; vascular excitement marked in the area supplied by the bronchial arteries; inflammation of serous ti......of the lung or the bronchial structures and the mucosa. Webster declares it best adapted to control vascular disturbances in the area supplied by the bronchial arteries, and suggests that by reserving...2
   ...raction of the sphincter and perineum; sense of contraction in the rectum, with constipation due to vascular engorgement of the pelvic viscera; scybalous feces; sticking pains in the heart, larynx or ......it usually does not cure, though it may do so early in their course. It is to be used when there is vascular engorgement of the pelvic viscera, with a sense as if a foreign body were lodged in the rec......ibed. It does, however, relieve discomfort in the rectum without apparent lesion other than that of vascular engorgement. Many value collinsonia in gastro-intestinal irritation with torpor of the por...2
   The rhizome and rootlets of Convallaria majalis, Linné (Nat. Ord. Liliaceae.) Common Name: Lily of the Valley. Principal Constituents.Two... / ...the more often indicated, sometimes convallaria is more effective on account of the disturbing extravascular effects of the former. Convallaria appears to act best in those cases of circulatory failur... / ...carditis and endocarditis, using it in fractional doses. Convallaria is of less service in stenosis of the aorta than in mitral disorders.2
   The entire plant and oil of Erechtites hieracifolia, Rafinesque (Nat. Ord. Compositae.) A rank weed throughout the United States. Common Name:... / ... acid fermentation and flatulence are present. Its ultimate effect upon the circulation is to raise vascular tension. It is eliminated most largely by the lungs, and to a lesser extent by the kidneys ... / ...edema. For this purpose the dose should not be over one drop of the oil, in emulsion, well diluted. Usually the oil is administered on sugar.2
   The leaves of Gaultheria procumbens, Linné (Nat. Ord. Ericaceae). Damp woods and sandy soils of eastern third of the United States. Common... / ...cians have advised both gaultheria and its oil for the relief of hepatic congestion and in sluggish vascularity and engorgement of the intestinal glands, as well as to relieve hemorrhoids by overcomin... / ...of infants. Gaultheria is an agent of special value as a flavoring agent and preservative for water-dispensed medicines in the summer season. Fo2
   The leaves, bark and twigs of Hamamelis virginiana, Linné (Nat. Ord. Hamamelidaceae), collected in the autumn. Common in the United States.... / ...ic effect upon venous debility, acting upon the coats of the veins throughout the body. Unlike some vascular remedies its action is not merely local, but extends throughout the whole venous system. It...2
   ...in). Preparation.Specific Medicine Horse Chestnut. Dose, 1/10 to 10 drops. Specific Indications.Vascular engorgement, with dull, aching pain and fullness, throbbing of the vessels, and general mal......llness, throbbing of the vessels, and general malaise; visceral neuralgia; disturbances reflex from vascular congestion of the rectum. Action and Therapy.The action and therapeutic uses of hippocast...2
   ... volatile oil. Preparation.Specific Medicine Lycopus. Dose, 1 to 60 drops. Specific Indications.Vascular excitement, with rapid, tumultuous action of the heart, but lacking power; hemorrhage, pass...... duplicates its value in circulatory disturbances. Apparently gits force is chiefly expended on the vascular structures and the sympathetic nervous system. Its sedative action is most certain when the......itated. Normal secretion is favored by it, and blood-making and nutrition improved. Upon the cardio-vascular system it has been compared in action to digitalis, though it is far less powerful than tha...2
   The whole plant of Senecio aureus, Linné (Nat. Ord. Compositae). Northern and western parts of the United States. Dose, 5 to 60 grains. Common... / ...leucorrhea and impairment of function; vaginal prolapse; slight uterine prolapse; pelvic weight and vascular engorgement; increased flow of mucus or muco-pus from weakness; suppressed or tardy menstru... / ...urination. The dose of specific medicine senecio, the best preparation of it, is from five to sixty drops in water, three or four times a day.2
   ...d inflammations; irritation of nerve centers due to an excited circulation; convulsions, with great vascular excitement, full pulse, and cerebral hyperaemia; puerperal eclampsia; red stripe down cente...... The most characteristic action of veratrum is its effects upon the movements of the heart and upon vascular tonus. The pulse-rate has been lowered to thirty-five beats -a minute with this agent, a co...2
Physician's Materia Medica on Vascular
   A stearopten obtained from CINNAMOMUM CAMP:-roRA, F. Nees & Eber. Stimulates the nervous and vascular systems: antispasmo dic, anaphrodisiac. Prescribed in acute coryza, in diarrhea, in some spasmodic affections, and to allay maniacal and sexual excitement. Dose, 0.06 to0.3 Grm. (1 to 5 grs.); in low fevers and in mania 0.6 to 1.3 Grm. (10 to 20 grs.) may be given.3
Physician's Therapeutics Memoranda on Vascular
   Seek the cause and govern treatment accordingly. Distinguish articularly congestive from anemic headaches. In the former ergot and vascular sedatives are useful, in the latter stimulating remedies are indicated. See that excretions are normal, that the eyes are not under strain from errors of refraction. that hygenic conditions are good and that the patient takes suflicient exercise and recreation.3
References
2) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
3) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.