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Granulomatosis with polyangiitis (GPA), previously known as Wegener's granulomatosis, is a rare disease. It is a type of vasculitis, or inflammation of the blood vessels. The inflammation limits the flow of blood to important organs, causing damage. It can affect any organ, but it mainly affects the sinuses, nose, trachea (windpipe), lungs, and kidneys.

The cause of GPA is unknown. It can affect people at any age. Men and women are equally affected. It is more common in whites. Symptoms may include joint pain, weakness, tiredness, and cold symptoms such as a runny nose that doesn't get better. Doctors use blood tests, chest X-rays, and biopsies to diagnose GPA and rule out other causes of the symptoms.

Early treatment is important. Most people improve with medicines to slow or stop the inflammation.

Cytoxan FDA Approved Drugs

CYCLOPHOSPHAMIDE [CyclophosphamideC7H15Cl2N2O2PH2O]
1gm/vial (injection injectable)
25mg (oral capsule)
2gm/vial (injection injectable)
500mg/vial (injection injectable)
50mg (oral capsule)
Baxter HlthcareMay 21, 2008
Jiangsu Hengrui MedOct 31, 2014
West-ward Pharms IntSep 16, 2013
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side effects
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WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.