Dial
What is depression?
Depression is more than a feeling of being sad or irritable for a few days. It's a serious mood disorder. As one of the most common mental disorders in the United States, depression can affect how you think, feel, and your everyday life. You may not know why you feel this way, but even basic daily activities such as sleeping, eating, or working may become difficult. Depression often needs long-term treatment but getting help at the earliest sign of a problem can help manage your symptoms.
What are the different types of depression?The most common types of depression are major depression and persistent depressive disorder.
- Major depression symptoms include a depressed mood or a loss of interest. Symptoms affect your daily activities and last for at least two weeks.
- Persistent depressive disorder (also called dysthymia or dysthymic disorder) has less severe depressive symptoms, but they last longer, usually for at least two years.
Other types of depression can include:
- Seasonal affective disorder comes and goes with the seasons. It usually starts in late fall and early winter and goes away during the spring and summer.
- Bipolar disorder is sometimes called manic depression. This mood disorder can cause intense mood swings.
- Depression with symptoms of psychosis is a severe form of depression that also has delusions (false beliefs) or hallucinations (seeing, hearing, or feeling something that isn't there).
There are a variety of things that may cause depression, including genetic, biological, environmental, and psychological factors. Depression can happen at any age and can affect anyone, but it's more common in women. This is often due to the physical and hormonal changes that women have during menstruation, pregnancy, the postpartum period, and menopause. Other mental disorders or chronic medical conditions such as diabetes, cancer, or heart disease may occur with depression. This may make the chronic condition or depression worse.
In some cases, there is no clear cause for depression.
Who is at risk of depression?You may be at a higher risk of depression if you have a close relative who has it or another mental health disorder. Going through trauma or stressful life events may raise your risk even more.
What are the symptoms of depression?Depression doesn't look the same on everyone. The type and number of symptoms of depression can vary and don't always appear like sadness. Depression may affect you differently based on your:
- Age. The symptoms of depression may be different in a child, who may appear more irritable than sad. Teens may act out or have excessive sleepiness. The symptoms for an older adult may not be as obvious as other age groups.
- Sex. Men often show symptoms and coping behaviors differently than women. Rather than sad, men may appear angry or irritable.
- Medical conditions. Some medicines and medical conditions may cause symptoms that look like depression. Chronic conditions may make depression worse.
Symptoms of depression are ongoing and affect your day-to-day life. They can include:
- Feeling sad or "empty"
- Losing interest in favorite activities
- Overeating, or not wanting to eat at all
- Sleeping too much, or not enough
- Feeling very tired
- Feeling hopeless, irritable, anxious, or guilty
- Having aches and pains, headaches, cramps, or digestive problems
- Having thoughts of death or suicide
- Changing moods or behaviors
- Increasing use of alcohol or drugs
- Isolating from family and friends
If you think you have depression, talk to your health care provider or a mental health provider. To be diagnosed with depression, your provider may use many tools:
- A medical history will include asking about your symptoms and family history. To be diagnosed with depression, your symptoms must occur most of the day, nearly every day, for at least two weeks. One of the symptoms must be a depressed mood or a loss of interest in most activities.
- Medical tests may be done to rule out other medical conditions. Certain medicines and medical conditions (such as viruses or thyroid disorders) may cause symptoms like depression.
- A physical exam to make sure another issue isn't causing your symptoms.
- A mental health evaluation by your provider or a mental health provider.
Depression may need long-term treatment. Most treatments include medicines and/or psychotherapy (talk therapy):
- Medicines such as antidepressants may help control your symptoms. You may need to try several medicines to find which works best for you. Medicine may take time to work and can have side effects. Don't stop taking your medicine without first talking with your provider. Contact your provider if you have any concerns about side effects from the medicine.
- Psychotherapy (talk therapy) under the care of a mental health provider can help you recognize and change troubling emotions, thoughts, and behaviors. This may be done one-on-one or in a group setting. It can give you and your family support, education, skills, and coping strategies.
- Light therapy has been shown to be effective for seasonal affective disorder (SAD).
- Other treatments options may be considered if treatment isn't working or if depression is severe. These may include:
- Electroconvulsive therapy (ECT) is a brain stimulation procedure that uses a mild electric current when you are under general anesthesia. ECT is most often used for severe depression that is not getting better with other treatments.
- Repetitive transcranial magnetic stimulation (rTMS) is a brain stimulation procedure that uses magnetic waves to relieve depression. It's not as powerful as ECT, but with rTMS, you don't need anesthesia. It also has a low risk of negative effects on your memory and thinking.
Most cases of depression can't be prevented, but healthy lifestyle changes can have long-term benefits for your mental health. These can include:
- Getting regular exercise
- Having a consistent sleep schedule
- Controlling stress
If you, or someone you love is depressed, see your provider or a mental health provider. It's important to get treatment at the earliest sign of a problem.
If you or someone you know has thoughts of hurting themselves or attempting suicide, get help right away. If it is an emergency, dial 911.
NIH: National Institute of Mental Health
Dial FDA Approved Drugs
- Administration of a composition comprising insulin complexed with a diketopiperazine..
- Administration of a composition comprising insulin complexed with microparticles of a diketopiperazine..
- Administration of fdkp microparticles comprising insulin..
- Method of aerosolizing/deagglomerating an insulin dry powder for use in treating diabetes mellitus via oral inhalation using an inhaler with a cartridge containing the insulin dry powder..
- Method of controlling glycemia in diabetics by administering an initial dose of insulin-fdkp with a meal; determining blood glucose level 1-2 hrs after and administering a supplemental dose of insulin-fdkp if postprandial glucose level is >140 mg/dl.
- Method of delivering to a patient with diabetes mellitus in a single inhalation, greater than 75% of a dry powder dose comprising insulin and fumaryl diketopiperazine using a high resistance to flow dry powder inhaler..
- Pulmonary administration of a compisition comprising insulin bound to a diketopiperazine..
- Pulmonary administration of a composition comprising insulin bound to a complexing agent..
- Pulmonary administration of an insulin composition comprising fdkp at the beginning of a meal to a patient also being treated with a long-acting insulin..
- Treatment of a patient having diabetes mellitus with a prandial rapid acting insulin..
- Treatment of diabetes mellitus with an inhaled insulin to improve glycemic control using a dry powder inhalation system comprising an inhaler, a cartridge and a dry powder medicament comprising insulin in a single inhalation.
- Treatment of patient having diabetes mellitus via oral inhalation of fdkp microparticles comprising insulin.
- Use of an inhaler to administer dry powder medicament.
- Method of reducing risk of myocardial infarction, stroke and death.
- Method of inhibiting platelet aggregation.
- Reduction of the rate of cardiovascular death, myocardial infarction, and stroke in patients with a history of myocardial infarction.
- Reduction of the rate of cardiovascular death, myocardial infarction, and stroke in patients with acute coronary syndrome or a history of myocardial infarction.
- Reduction of the rate of thrombotic events in patients with acute coronary syndrome.
- Treatment of an arterial thrombotic complication in a patient with coronary artery, cerebrovascular or peripheral vascular disease.
- Treatment of arterial thrombotic complications selected from the group consisting of unstable angina, thrombotic or embolic stroke, transient ischaemic attacks, peripheral vascular disease and myocardial infarction.
- Treatment of myocardial infarction and stroke in patients with acute coronary syndrome or a history of myocardial infarction.
- Treatment of myocardial infarction in patients with acute coronary syndrome or a history of myocardial infarction.
- Treatment of myocardial infarction.
- Treatment of post-myocardial infarction.
- Treatment of stable and unstable angina.
- Treatment of stroke in patients with acute coronary syndrome or a history of myocardial infarction.
- Treatment of stroke.
- Treatment of thrombotic stroke.
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Mayne PharmaFeb 3, 1987
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West-ward Pharms IntApr 3, 1987
- Treatment of hypertension.
- Use of valsartan to reduce cardiovascular mortality in clinically stable patients with left ventricular failure or left ventricular dysfunction following myocardial infarction.
- Peritoneal dialysis solution.
- Treatment of conditions for which an aldosterone receptor blocker is indicated, such as hypertension, heart failure, and post-myocardial infarction.
- Treatment of conditions related to hyperaldosteronism such as hypertension and cardiac insufficiency, with eplerenone.
- Treatment of hypertension.
- Use of eplerenone in combination with an angiotensin converting enzyme (ace) inhibitor (and optionally a diuretic) for treating congestive heart failure and hypertension.
- Use of eplerenone in combination with an angiotensin converting enzyme (ace) inhibitor for treating hypertension.
- Method of treating diabetes comprising administering a compound such as alogliptin.
- Method of treating diabetes comprising administering alogliptin.
- Methods of lowering elevated post prandial blood glucose levels comprising administering a dipeptidyl peptidase inhibitor.
- Methods of modifying glucose metabolism and treating diabetes comprising administering a dipeptidyl peptidase inhibitor and one or more other therapeutic agents such as metformin.
- Methods of reducing the side effects of active components administered to a diabetic patient comprising administering an insulin sensitivity enhancer such as pioglitazone in combination with an insulin secretion enhancer.
- Methods of treating diabetes comprising administering a dipeptidyl peptidase inhibitor and metformin.
- A method of myocardial perfusion imaging and increasing coronary blood flow.
- Method for stimulating coronary vasodilation for purposes of imaging the heart.
- Method for stimulating coronoary vasodilation for purposes of imaging the heart.
- Method of myocardial imaging.
- Method of producing coronary vasodilation without peripheral vasodilation.
- Reduction of cardiac tissue damage associated with myocardial infarction.
- Treatment or prevention of stroke.
- Method of treating diabetes comprising administering a compound such as alogliptin.
- Method of treating diabetes comprising administering alogliptin.
- Methods of lowering elevated post prandial blood glucose levels comprising administering a dipeptidyl peptidase inhibitor.
- Methods of modifying glucose metabolism and treating diabetes comprising administering a dipeptidyl peptidase inhibitor and one or more other therapeutic agents such as metformin.
- Methods of reducing the side effects of active components administered to a diabetic patient comprising administering an insulin sensitivity enhancer such as pioglitazone in combination with an insulin secretion enhancer.
- Methods of treating diabetes comprising administering a dipeptidyl peptidase inhibitor and metformin.
- A method of reducing the capacity of extended release nicotinic acid to provoke a flushing reaction by pretreating an individual with a flush inhibiting agent prior to the administration of the extended release nicotinic acid.
- Method of treating hyperlipidemia with nicotinic acid by dosing once per day in the evening or at night.
- Reduction in elevated tc and ldl-c by dosing once per day in the evening or at night, with pretreatment with a flush inhibitin agent such as aspirin.
- Reduction in elevated tc and ldl-c by dosing once per day in the evening or at night.
- Reduction in risk of recurrent nonfatal myocardial infarction by dosing once per day in the evening or a t night, with pretreatment with a flush inhibitin agent such as aspirin.
- Reduction in risk of recurrent nonfatal myocardial infarction by dosing once per day in the evening or at night.
- Reduction in tg by dosing once per day in the evening or at night, with pretreatment with a flush inhibiting agent such as aspirin.
- Reduction in tg by dosing once per day in the evening or at night.
- Treatment of primary and mixed dyslipidemia by dosing once per day in the evening or at night, with pretreatment with a flush inhibiting agent such as aspirin.
- Treatment of primary and mixed dyslipidemia by dosing once per day in the evening or at night.
- Method of treating diabetes comprising administering a compound such as alogliptin.
- Method of treating diabetes comprising administering alogliptin.
- Methods of lowering elevated post prandial blood glucose levels comprising administering a dipeptidyl peptidase inhibitor.
- Methods of modifying glucose metabolism and treating diabetes comprising administering a dipeptidyl peptidase inhibitor and one or more other therapeutic agents such as metformin.
- Methods of reducing the side effects of active components administered to a diabetic patient comprising administering an insulin sensitivity enhancer such as pioglitazone in combination with an insulin secretion enhancer.
- Methods of treating diabetes comprising administering an insulin sensitivity enhancer such as pioglitazone in combination with an insulin secretion enhancer.
- Methods of treating diabetes comprising administering a dipeptidyl peptidase inhibitor and metformin.
- Acute myocardial infarction.
- Method of treating hypertension.
- Method of treatment of heart failure.
- Reduction of mortality in acute mycardial infarction.
- Treatment of heart failure.
- Treatment of hypertension.
- Treatment of myocardial infarction.
- Treatment of diabetes with an amylin agonist, including with insulin.
- Treatment of diabetes with an amylin agonist.
- Use of an amylin agonist to reduce gastric motility and treat post prandial hypergylcemia.
Home Remedies for Dial
   Garlic (Allium sativum L.) kills bacteria and some viruses. Place half a clove of garlic between the teeth and each cheek and/or suck on clove. Alternately, buy garlic lozenges and use as directed. Garlic has antiviral, anti-fungal and antibacterial properties.
Mechanism - allyl 2-propenethiosulfinate or diallyl thiosulfinateGuydeMaupassant | August 7th, 2020
   ...rink 1 time per day.
This may just be what we need to help prevent COVID-19 infections!
Sulfur Compounds: aliin, allicin, ajoene, allylpropl, diallyl, trisulfide, sallylcysteine, vinyldithiines, S-allylmercaptocystein, and others.
Amino acids: arginine and others.
Enzymes: allinase, pe......ines, S-allylmercaptocystein, and others.
Amino acids: arginine and others.
Enzymes: allinase, peroxidases, myrosinase, and others.
Allicin (diallyl thiousulfinate or diallyl disulfide) does not exist in garlic until it is crushed or cut. Crushing the garlic bulb activates the enzyme allin...NathanielHawthorne | August 13th, 2020
Felter's Materia Medica on Dial
   The flowering tops and leaves of Artemisia Absinthium, Linné (Nat. Ord. Compositae); Europe, Siberia, Barbary, Newfoundland, and the United... / ... in the integument of the hypogastrium. The French liquer Absinthe, which is a viscous alcoholic cordial, and Wermuth, a German beer, both depend upon wormwood for their activity. Therapy.External. ... / ...used for the expulsion of the intestinal parasites-Ascaris vermicularis and Ascaris lumbricoides. The oil may be given in doses of 1 to 5 drops. 3
   The root of Apocynum cannabinum, Linné (Nat. Ord. Apocynaceae) gathered in autumn after the leaves and fruit have matured. Grows throughout the... / .... On the other hand, the feeble pulse, soft and of little force, indicates its selection as the remedial agent. The atonic state which readily permits of exudation from the blood vessels is the ideal ... / ...may be looked for. Under these circumstances we have removed enormous dropsical swellings with it, giving quick relief from dyspnea and3
   The dried flower-heads of Arnica montana, Linné (Nat. Ord. Compositae). A perennial of Siberia and the cooler parts of Europe; also found in... / ...tion; lack of control over urine and feces; sleeplessness from impeded respiration; and dull praecordial pain from heart strain; muscular pain and soreness when the limbs are moved; tensive backac...3
   The outer rind of the ripe, fresh fruit of Citrus Aurantium. sinensis, Gallesio (Nat. Ord. Rutaceae) Common Names: Sweet Orange Peel (of Sweet... / ... to be given during fevers and the exanthemata where acids are craved. It is par excellence the remedial agent in scurvy of infants, as well as adults, and if given early will abort this unpleasant di...3
   ... action, whether feeble, irregular, or tumultuous; cardiac disorders with mental depression, praecordial oppression, and apprehension of danger and death; nervous disorders with feeble heart action; t......sion, often amounting to hypochondria and fear of impending death. Associated with these are praecordial weight and oppression and difficult breathing. The control over the nervous system is somewhat ...3
   The rhizome and roots of Caulophyllum thalictroides (Linné, Michaux (Nat. Ord. Berberidaceae). In rich woods in the eastern half of the United... / ... with greater safety than forceps. As an ingredient of the Compound Syrup of Mitchella (Mother's Cordial), it is still relied upon by some physicians as a good partus praeparator. Caulophyllum is a go... / ...of strength and rapid involution of the womb following labor. The dose of the syrup is from 2 fluidrachms to 1/2 fluidounce, 2 or 3 times a day.3
   The rhizome and rootlets of Convallaria majalis, Linné (Nat. Ord. Liliaceae.) Common Name: Lily of the Valley. Principal Constituents.Two... / ...ndly is an ideal heart stimulant, and such is convallaria. Convallaria relieves the sense of praecordial oppression and faintness that so frequently follows prostrating diseases. Not alone is it a hea... / ...carditis and endocarditis, using it in fractional doses. Convallaria is of less service in stenosis of the aorta than in mitral disorders.3
   The ripe fruit and bark of (1) Crataegus Oxyacantha, Linné, and (2) other species of Crataegus. (Nat. Ord. Rosaceae) 1. England and other parts... / ...depression or neurasthenia; mitral regurgitation, with valvular insufficiency; cardiac pain; praecordial oppression; dyspnea; rapid and feeble heart action; marked anemia, associated with heart irreg... / ...trial; and as yet with no rational explanation of its reputed powers. The smaller doses are suggested as more likely to succeed than full doses.3
   The flowering tops and leaves of Eupatorium perfoliatum, Linné (Nat. Ord. Compositae). Swamps and low meadows throughout the United States. Dose,... / ... a rule, followed by perspiration; there is deepseated, aching pain, as if in the bones, praecordial oppression, and great thirst. If, however, the fever lasts all day, slight sweating may occur a... / ...tonic and stomachic, when given in small doses it improves the appetite and digestion and thus favors a more rapid and perfect convalescence.3
   The rhizome and rootlets of Veronicastrum virginicum (L.) Farw., (Leptandra virginica, Nuttall), (Nat. Ord. Scrophulariaceae). A tall perennial plant indigenous to the eastern half... / ... 20 drops every hour until the diarrhea ceases. Glyconda may be substituted for the neutralizing cordial, if sugar is contraindicated.3
   The leaves, tops, and seeds of Lobelia inflata, Linné (Nat. Ord. Lobeliaceae). Abundant in the United States. Dose, 1 to 60 grains. Common... / ...current moving with difficulty; short, labored breathing; sense of suffocation; dyspnea with praecordial oppression; pain in chest of a heavy, sore, or oppressive character; pulmonary apoplexy (full d...3
   The whole herb Lycopus virginicus, Linné (Nat. Ord. Labiatae). Common in shady, moist and boggy places throughout the United States. Dose, 1 to... / ...of heart disease characterized by irritability, irregularity, and weakness, with dyspnea and praecordial oppression. Lycopus powerfully increases the contraction of the non-striated muscular fibers, p... / ...in simple diarrhea (lientery), dysenteric diarrhea, and especially in the diarrhea of phthisis, and the gastric disturbances of the drunkard.3
   The dried flower-heads of Matricaria Chamomilla, Linné (Nat. Ord. Compositae). Wastes of Europe, Asia, and Australia. Dose, 1 to 60... / ..., fail to show decided so-called physiological action. Matricaria, simple and safe as it is, is remedially potent. Could it more generally have taken the place of soothing syrups, so largely destr... / ...to the actual pain suffered. This remedy should be resorted to when one is tempted to employ opiates and other more powerful pain relievers.3
   The leaves and tops of Mentha piperita, Smith (Mentha X piperita L.) (Nat. Ord. Labiatae). Europe and the United States. Dose, 60 to 120... / ...llay nausea and vomiting, and to break up a cold. It forms a part of the well-known Neutralizing Cordial. The essence is a common and unexcelled carminative for gastrodynia and the flatulent colic of ... / ...and gives relief in the cough of acute bronchitis and pneumonia.3
   The whole plant of Mitchella repens, Linné (Nat. Ord. Rubiaceae). Dry... / ...ose, 5 to 60 drops. 2. Syrupus Mitchellae Compositus, Compound Syrup of Partridgeberry (Mothers' Cordial). (Contains Mitchella, Helonias, Viburnum Opulus and Caulophyllum, Brandy, Sugar and Essence of...... previously occurred. As a female regulator it has also had many devoted advocates. The Mother's Cordial is a popular and more rational preparation.3
Physician's Materia Medica on Dial
   The corm, also the seed of COLCHICUM AUTUMNALE. Lin. Pur gative, diuretic, diaphoretic, nauseant. Prescribed especially in gout, in which disease it is our most important remedial agent. Dose of the seed or root in substance, 0.13 to 0.5 Grm. (2 to 8 grs.).4
   A ferruginous tonic, each fluidrachm containing; Iron Citro peptonate, 1% grs.; ManganeseCitropeptonate, 1/4 gr. The preparation resembles dialysed iron in its freedom from astringency and acidity, but it has the advantage over that preparation in the fact that the iron is presented in the form of an organic compound which is readily assimilable. Clinical experience declares it a most eflicient agent in all conditions in which a blood-euriching tonic is indicated. Dose, 4 c. c. (1 fluidrachm) a4
   Stomachic, laxative, antacid. A favorite remedy with many for certain dyspeptlc conditions, in which constipation and acidity of the stomach are prominent symptoms. Each fluidrachm repre sents; Rhubarb, 2 1/4 grs.; Cinnamon 1 1/8 grs.; Golden-seal, 1 1/8 grs.; Potassium Bicarb., 2 1/4 grs-; Oil Peppermint, 3-50 M Dose, 4 to 8 c. c. (1 to 2 fluidrachms) when distress is felt after eating. It is best taken as much as two hours after a meal.4
References
2) Motteshard, Tammy D. "The Benefits Of The Use Of Garlic In Herbal Preparations: Chemical Constituents", www.herballegacy.com/Motteshard_Chemical.html.
3) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
4) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.