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Dilation

What is uterine cancer?

Uterine cancer is a cancer that forms in tissues of the uterus, which is sometimes called the womb. The uterus is the place where a fetus grows during pregnancy.

There are two types of uterine cancer:

  • Endometrial cancer is the most common type. This type of cancer begins in the cells lining the uterus, known as the endometrium.
  • Uterine sarcoma is a rare, more aggressive cancer that is harder to treat. This type of cancer begins in muscle or other tissues in the uterus.
Who is more likely to develop uterine cancer?

Uterine cancer usually happens after menopause. The cause is unknown. However, some factors and conditions that change the balance of hormones in your body may increase your risk. These can include obesity or metabolic syndrome (a group of risk factors for certain health problems).

Other factors and conditions that may increase your risk for:

Endometrial cancer

  • Taking estrogen-only hormone replacement therapy (HRT) after menopause.
  • Having type 2 diabetes.
  • Starting menstruation at an early age or menopause at a later age.
  • Having never been pregnant.
  • Taking tamoxifen, a medicine used to prevent or treat breast cancer.
  • Having polycystic ovary syndrome.
  • Having a mother, sister, or daughter who has had endometrial cancer.
  • Having certain genetic conditions, such as Lynch syndrome.
  • Having endometrial hyperplasia (thickening of the uterine lining).

Uterine sarcoma

  • Having had past treatment with radiation therapy to the pelvis.
  • Taking tamoxifen, a medicine used to prevent or treat breast cancer.
What are the symptoms of uterine cancer?

The most common symptom of both endometrial cancer and uterine sarcoma is abnormal vaginal bleeding. Both types of uterine cancer may also cause pelvic pain or pressure, unusual vaginal discharge, or an enlarged uterus or pelvic mass.

Less common symptoms may include urinating (peeing) often, having trouble urinating, or pain during sexual intercourse.

How is uterine cancer diagnosed?

If you have symptoms of uterine cancer, your health care provider may:

  • Ask about your medical history and family health history.
  • Do a pelvic exam.
  • Order imaging tests.
  • Suggest a biopsy or a minor procedure called dilation and curettage (D & C) to check the lining of your uterus.
What are the treatments for uterine cancer?

Treatment may depend on your health, how much cancer you have, and whether it has spread. The most common treatment is having a hysterectomy, which is surgery to remove the uterus. Sometimes the surgery also removes the ovaries and fallopian tubes.

You may have more than one type of treatment. Other treatments may include:

  • Hormone therapy
  • Radiation therapy
  • Chemotherapy
Can uterine cancer be prevented?

There is no sure way to prevent uterine cancer. But you can do things that may help lower your risk such as aiming for a healthy weight, getting regular physical activity, and talking to your provider about the benefits and risks of hormone therapy.

NIH: National Cancer Institute

Dilation FDA Approved Drugs

LEXISCAN [RegadenosonC15H18N8O5H2O]
RX
-
0.4mg/5ml (0.08mg/ml) (intravenous solution)
AstellasApr 10, 2008
  • A method of myocardial perfusion imaging and increasing coronary blood flow.
  • Method for stimulating coronary vasodilation for purposes of imaging the heart.
  • Method for stimulating coronoary vasodilation for purposes of imaging the heart.
  • Method of myocardial imaging.
  • Method of producing coronary vasodilation without peripheral vasodilation.
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

PHENYLEPHRINE HYDROCHLORIDE [Phenylephrine HydrochlorideC9H13NO2ClH]
RX
-
10% (ophthalmic solution/drops)
10mg/ml (10mg/ml) (iv (infusion) solution)
2.5% (ophthalmic solution/drops)
Akorn IncJan 15, 2015
Paragon BioteckMar 21, 2013
West Ward Pharm CorpDec 20, 2012
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.


WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Felter's Materia Medica on Dilation

CALUMBA (Jateorhiza palmata)JAPA2
   The root of Jateorhiza palmata (Lamarck), Miers (Nat. Ord. Menispermaceae). A climbing perennial, the Kalumb of the Southeast coast of Africa.... / ...d be given immediately before meals. Their effect upon the stomach is to increase local circulatory dilation, a freer flow of gastric juice, increase of mucus, and increased muscular action. On accoun... / ...local action, and indirectly, by favoring better digestion, the quality of the blood is improved, hence its value in anemia during convalescence.1

CAMPHORA
   A stearopten (having the nature of a ketone) derived from Cinnamomum Camphora. (Linné), Nees et Ebermeier (Nat. Ord. Lauraceae). China and... / ...ite Wax, White Petrolatum, and Benzoinated Lard.) For external use. Action.—Camphor causes a local dilation of the capillaries of the skin, producing warmth, redness, and sometimes itching. Slight an... / ...due to gaseous distention of the stomach, or to nervous irritability. In occipital headache, from mental strain, or overstudy, small doses of 1

GELSEMIUM
   The dried rhizome and roots of Gelsemium sempervirens (Linné,) Aiton (Nat. Ord. Loganiaceae). Dose, 1/10 to 1 grain. Common Names: Yellow... / ...an convulsions do not occur. Both gelsemium and gelsemine, when dropped into the eye, cause violent dilation of the pupil, with accompanying paralysis of accommodation. The mydriasis is not so lasting... / ...great restlessness and excitation” are the classic indications for it as first formulated by Scudder, and these stand among the truest of speci1

LUPULINUM
   Lupulin. The glandular powder separated from the strobiles of Humulus Lupulus, Linné (Nat. Ord. Cannabaceae), the common Hop. (See... / ...ntative changes in the stomach, thus proving useful in yeasty indigestion with acid eructations and dilation of the stomach, and in the headache due to such gastric disturbance.1

OLEUM TIGLII
   Croton Oil. A fixed oil expressed from the seeds of Croton Tiglium, Linné (Nat. Ord. Euphorbiaceae). East Indies and Molucca, and Philippine... / ...nd as a revulsive in cerebral congestion and apoplexy, to lower intracranial blood pressure through dilation of the vessels of the bowels. It is the most efficient purgative in lead colic with obstipa... / ...to avoid it, in children and the feeble and pregnant, nor where hemorrhoids, intestinal or renal inflammation, or peritonitis are present.1


References

1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.