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What is bipolar disorder?

Bipolar disorder is a mood disorder that can cause intense mood swings:

  • Sometimes you may feel extremely "up," elated, irritable, or energized. This is called a manic episode.
  • Other times you may feel "down," sad, indifferent, or hopeless. This is called a depressive episode.
  • You may have both manic and depressive symptoms together. This is called a mixed episode.

Along with mood swings, bipolar disorder causes changes in behavior, energy levels, and activity levels.

Bipolar disorder used to be called other names, including manic depression and manic-depressive disorder.

What are the types of bipolar disorder?

There are three main types of bipolar disorder:

  • Bipolar I disorder involves manic episodes that last at least 7 days or manic symptoms so severe that you need immediate hospital care. Depressive episodes are also common. Those often last at least two weeks. This type of bipolar disorder can also involve mixed episodes.
  • Bipolar II disorder involves depressive episodes. But instead of full-blown manic episodes, there are episodes of hypomania. Hypomania is a less severe version of mania.
  • Cyclothymic disorder, or cyclothymia, also involves hypomanic and depressive symptoms. But they are not as intense or as long-lasting as hypomanic or depressive episodes. The symptoms usually last for at least two years in adults and for one year in children and teenagers.

With any of these types, having four or more episodes of mania or depression in a year is called "rapid cycling."

What causes bipolar disorder?

The exact cause of bipolar disorder is unknown. Several factors likely play a role in the disorder. They include genetics, brain structure and function, and your environment.

Who is at risk for bipolar disorder?

You are at higher risk for bipolar disorder if you have a close relative who has it. Going through trauma or stressful life events may raise this risk even more.

What are the symptoms of bipolar disorder?

The symptoms of bipolar disorder can vary. But they involve mood swings known as mood episodes:

  • The symptoms of a manic episode can include
    • Feeling very up, high, or elated
    • Feeling jumpy or wired, more active than usual
    • Having a very short temper or seeming extremely irritable
    • Having racing thoughts and talking very fast
    • Needing less sleep
    • Feeling like you are unusually important, talented, or powerful
    • Do risky things that show poor judgment, such as eating and drinking too much, spending or giving away a lot of money, or having reckless sex
  • The symptoms of a depressive episode can include
    • Feeling very sad, hopeless, or worthless
    • Feeling lonely or isolating yourself from others
    • Talking very slowly, feeling like you have nothing to say, or forgetting a lot
    • Having little energy
    • Sleeping too much
    • Eating too much or too little
    • Lack of interest in your usual activities and being unable to do even simple things
    • Thinking about death or suicide
  • The symptoms of a mixed episode include both manic and depressive symptoms together. For example, you may feel very sad, empty, or hopeless, while at the same time feeling extremely energized.

Some people with bipolar disorder may have milder symptoms. For example, you may have hypomania instead of mania. With hypomania, you may feel very good and find that you can get a lot done. You may not feel like anything is wrong. But your family and friends may notice your mood swings and changes in activity levels. They may realize that your behavior is unusual for you. After the hypomania, you might have severe depression.

Your mood episodes may last a week or two or sometimes longer. During an episode, symptoms usually occur every day for most of the day.

How is bipolar disorder diagnosed?

To diagnose bipolar disorder, your health care provider may use many tools:

  • A physical exam
  • A medical history, which will include asking about your symptoms, lifetime history, experiences, and family history
  • Medical tests to rule out other conditions
  • A mental health evaluation. Your provider may do the evaluation or may refer you to a mental health specialist to get one.
What are the treatments for bipolar disorder?

Treatment can help many people, including those with the most severe forms of bipolar disorder. The main treatments for bipolar disorder include medicines, psychotherapy, or both:

  • Medicines can help control the symptoms of bipolar disorder. You may need to try several different medicines to find which one works best for you. Some people need to take more than one medicine. It's important to take your medicine consistently. Don't stop taking it without first talking with your provider. Contact your provider if you have any concerns about side effects from the medicines.
  • Psychotherapy (talk therapy) can help you recognize and change troubling emotions, thoughts, and behaviors. It can give you and your family support, education, skills, and coping strategies. There are several different types of psychotherapy that may help with bipolar disorder.
  • Other treatment options include:
    • Electroconvulsive therapy (ECT), a brain stimulation procedure that can help relieve symptoms. It uses a mild electric current and is done while you are under general anesthesia. ECT is most often used for severe bipolar disorder that is not getting better with other treatments. It may also be used when someone needs a treatment that will work more quickly than medicines. This might be when a person has a high risk of suicide or is catatonic (unresponsive).
    • Repetitive transcranial magnetic stimulation (rTMS), a brain stimulation procedure that uses magnetic waves to relieve depression. It is not as powerful as ECT, but with rTMS, you don't need general anesthesia. It also has a low risk of negative effects on your memory and thinking.
    • Light therapy has been shown to be effective for seasonal affective disorder (SAD). Many people with bipolar disorder also find that their depression gets worse during certain seasons, usually in the fall and winter. Light therapy may help with their symptoms.
    • Healthy lifestyle changes, such as getting regular exercise, having a consistent sleep schedule, and keeping a mood journal, can also help with your symptoms.

Bipolar disorder is a lifelong illness. But long-term, ongoing treatment can help manage your symptoms and enable you to live a healthy, successful life.

NIH: National Institute of Mental Health


WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Felter's Materia Medica on Several

AGAR
   A dried substance of mucilaginous character abstracted from several species of sea weeds (marine algae) growing along the coast of Asia. Most of it comes from Japan.... / A dried substance of mucilaginous character abstracted from several species of sea weeds (marine algae) growing along the coast of Asia. Most of it comes from J... / ...Biscuits, bread, and crackers are prepared from it and may be procured in the general trade. Agar is also used as a culture medium in making labaratory cultures. 1

ALOEALOE
   The dried juice of the leaves of several species of Aloe: (1) Aloe Perryi, Baker; (2) Aloe vera, Linné; (3) Aloe ferox, Miller. (Nat. Ord. Liliaceae). Barbadoes, Africa and the... / The dried juice of the leaves of several species of Aloe: (1) Aloe Perryi, Baker; (2) Aloe vera, Linné; (3) Aloe ferox, Miller. (Nat... / ...melancholia—aloes is probably the best that can be given. The improvement in the mental state often will be commensurate with the betterment of the intestinal torpor. 1

APOCYNUM CANNABINUM
   The root of Apocynum cannabinum, Linné (Nat. Ord. Apocynaceae) gathered in autumn after the leaves and fruit have matured. Grows throughout the... / ...vere watery purging, which may occur suddenly, when the drug has been administered persistently for several weeks. Therapy.—No remedy in the Eclectic materia medica acts with greater certainty than d... / ...may be looked for. Under these circumstances we have removed enormous dropsical swellings with it, giving quick relief from dyspnea and1

BALSAMUM PERUVIANUM
   A balsam obtained from Toluifera Pereirae (Royle) Baillon. San Salvador in Central America; called Balsam of Peru because first exported to Europe... / ...revived in surgery, applying it in 5 to 15 per cent solutions in castor oil, and covering well with several layers of gauze to allow of free drainage. This method is one of the best forms of treatment... / ...balsam should not be used in inflammatory or febrile conditions; and its use should be discontinued if it produces gastro-intestinal irritation.1

CAFFEA
   The seeds of Caffea arabica, Linné (Nat. Ord. Rubiaceae). Native of Arabia-Felix and Ethiopia; and extensively cultivated in Asia and America... / ...rtion. Coffee removes drowsiness after a heavy meal, and may produce wakefulness that will last for several hours. If coffee be withheld from one who is accustomed to its stimulus, physical and mental... / ...preferably without sugar or cream; for use in narcotic poisoning very strong, “black coffee” may be given freely, both by mouth and per rectum.1

CARBO LIGNI
   Charcoal prepared by burning soft wood. It must be kept in tightly-closed vessels. Common Names: Charcoal, Wood Charcoal; Synonym: Carbo... / ... rectum. Why this checks it I can not tell; that it does it I have the evidence of my own eyes. For several years I have employed the second decimal trituration as a remedy for passive hemorrhage with... / ...the belly-wall tumid and doughy, the tongue expressionless and pale with little coating and lenticular spots, or the coating may lift in patches.1

CASCARA SAGRADA
   The dried bark of Rhamnus Purshiana, De Candolle (Nat. Ord. Rhamnaceae). A shrub of Northern Idaho and the... / ...ific coast. Dose, 5 to 30 grains. Common Names: Sacred Bark, Chittem Bark. Principal Constituents.—Several resins, a volatile oil, and cascarin, a glucoside thought to be identical with frangulin obt... / ...Dose: One half to one teaspoonful at bedtime. If a more profound action is desired a half drachm of Specific Medicine Podophyllum may be added.1

CASTANEA
   The leaves of Castanea dentata (Marshall), Sudworth, collected in September or October while still green (Nat. Ord. Fagaceae). Native of Asia Minor, naturalized in Europe and... / ...(which is by far the best preparation) may be sweetened if desired, and given freely to the patient several times a day.1

CINNAMOMUM
   I. Cinnamomum Saigonicum. Dried bark of an undetermined species of Cinnamomum. Chiefly from China. II. Cinnamomum Zeylanicum. Dried bark of... / ...xtures give an agreeable sweetness and aroma and will help the medicine to preserve its balance for several days. Children invariably like the flavor. Even cinnamon can be overdone, however. It should...1

CRATAEGUSCRAN6
   The ripe fruit and bark of (1) Crataegus Oxyacantha, Linné, and (2) other species of Crataegus. (Nat. Ord. Rosaceae) 1. England and other parts... / ...ver-exertion or accompanying nervous explosions. Action and Therapy.—The bark, fruit and leaves of several species of the genus Crataegus have in the past been used as astringents and tonics. Though ... / ...trial; and as yet with no rational explanation of its reputed powers. The smaller doses are suggested as more likely to succeed than full doses.1

GELSEMIUM
   The dried rhizome and roots of Gelsemium sempervirens (Linné,) Aiton (Nat. Ord. Loganiaceae). Dose, 1/10 to 1 grain. Common Names: Yellow... / ...n, and cause vertigo, disturbed sight, and sometimes orbital pain. Continued small doses may, after several hours, provoke vomiting; otherwise it has little or no effect upon the stomach or bowels. To... / ...great restlessness and excitation” are the classic indications for it as first formulated by Scudder, and these stand among the truest of speci1

GRINDELIA
   The dried leaves and flowering tops of one or several species of Grindelia—as Grindelia camporum, Greene; or Grindelia squarrosa (Pursh), Dunal. (1) Marshes of California;... / The dried leaves and flowering tops of one or several species of Grindelia—as Grindelia camporum, Greene; or Grindelia squarrosa (Pursh), Dunal. ... / ...are dull pain with fullness over the spleen, sallow skin, debility and indigestion, with gastric distress. The bitter taste of grindelia is best disguised by chloroform.1

IRISIRIS
   The rhizome and roots of Iris versicolor, Linné (Nat. Ord. Iridaceae). Common in wet places in the United States. Dose, 5 to 20 grains. Common... / ...order to obtain satisfactory results at all, the use of the drug must be continued over a period of several months. In exophthalmic goitre it may be given early, but without great hope of doing more t...1

JACARANDAJACAR
   The leaves of Jacaranda procera, Sprengel (Nat. Ord. Bignoniaceae). A tree of Guiana and... / ...Brazil. Common Names: Carob Tree, Caroba, Caaroba. Principal Constituents.—Carobin, carobic acid, several resins, a balsam, and tannin. Preparation.—Specific Medicine Jacaranda. Dose, 5 to 20 drops...1

LIATRISLIBO7
   The rhizomes of several species of Liatris (Nat. Ord. Compositae). Middle and southern United States. Dose, 10 to 60 grains. Common Names: Button Snake Root (L. spicata); Blazing Star (L.... / The rhizomes of several species of Liatris (Nat. Ord. Compositae). Middle and southern United States. Dose, 10 to 60... / ...snake root derives its name from its traditional Indian reputation as a local alexipharmic (freshly-bruised root) for rattle-snake bite, a myth, it is needless to say, as yet unverified.1


WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Physician's Materia Medica on Several

BROMIDES
   Since the medicinal action of the several alkaline bromides is es sentially the same, and they are frequently prescribed in combina tion, they are grouped here under a single head. They are sedative to the cerebro-spinal centers and hence employed in epilepsy, in in fantile convulsions, in tetanus, in strychnine poisoning, in whooping cough and generally for quieting nervous excitement and in particu lar sexual erethism. In epilepsy a combination of two or more brom ides often gives better resul2

MORPHINE
   Alkaloid obtained from OPIUM, q. v. Anodyne, hypnotic, nar cotic. Used especially to combat pain, and to reinforce certain dia phoretics, particularly Ipecac. The several salts differ very little in their therapeutic action. Dose, 0.0015 to 0.02 Grm. (1-40 to 1-3 gr.).2

ROSEROSA5
   The petals of the flowers of ROSA CENTIFOLIA, Lin. (Pale Rose) and of R GALLICA, Lin. (Red Rose). The latter especially is as tringent, but is little used except as an adjuvant. [Confection Rose enters into the formulas of several oficial pills, such as Pills Aloes and Iron, U. S. P.].2

SODIUM PHOSPHATE
   Laxative and hepatic stimulant, sub-alkaline; prescribed to regulate the bowels in infancy, and as a remedy for morbid conditions dependant on torpidity of the liver. Dose for infants, 0.15 to 0.25 Grm. (2 to 4 grs.) several times a day; for adults as a hepatic stimulant, 1 to 4 Grru. (15 to 60 grs.), as a laxative 4 to 15 Grm. (1 to 4 drachms) or more.2


WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Physician's Therapeutics Memoranda on Several

CONJUNCTIVITIS
   In simple acute Conjunctivitis, boric acid, 10 grs. to the oz.’ in camphor water, or sodium... / ...ycerin and camphor water, 10 grs. to the oz., boric acid, copper sulphate, lapis divinus in dilute solution; touching with alum crystal; applications several times a day of hot water containing a little salt. Purulent Conjunctivitis calls for frequent cleansing and appli cation of active germicides ...2

FEVER
   The remedies commonly resorted to include; 1st cardiac or ar terial sedatives, particularly... / ...s of cold water which constitute a measure almost always serviceable, 4th sedatives and anodynes, which may well be combined with diaphoretics. These several classes of remedies must be suited to the individual case, bearing in mind the fact that fever is not in and of itself necessarily an evil thi...2

LARYNGITIS
   General treatment the same as in acute bronchitis or coryza, As special remedies, inhalations of steam from water to which has been added compound tincture benzoin or Antiseptine or in later stages eucalyptol (a few drops) or menthol, or these latter may be mixed with albolene and used in spray. As local application, at first Glyceroplasma or Phenol Camphor (a few drops several times a day), later oil turpentine or tincture iodine as counter-irritant.2


References

1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.