Toxin
Botox is a drug made from a toxin produced by the bacterium Clostridium botulinum. It's the same toxin that causes a life-threatening type of food poisoning called botulism. Doctors use it in small doses to treat health problems, including:
- Temporary smoothing of facial wrinkles and improving your appearance
- Severe underarm sweating
- Cervical dystonia - a neurological disorder that causes severe neck and shoulder muscle contractions
- Blepharospasm - uncontrollable blinking
- Strabismus - misaligned eyes
- Chronic migraine
- Overactive bladder
Botox injections work by weakening or paralyzing certain muscles or by blocking certain nerves. The effects last about three to twelve months, depending on what you are treating. The most common side effects are pain, swelling, or bruising at the injection site. You could also have flu-like symptoms, headache, and upset stomach. Injections in the face may also cause temporary drooping eyelids. You should not use Botox if you are pregnant or breastfeeding.
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.
Felter's Materia Medica on Toxin
APOCYNUM CANNABINUM
   The root of Apocynum cannabinum, Linné (Nat. Ord. Apocynaceae) gathered in autumn after the leaves and fruit have matured. Grows throughout the... / ...uents.A resinous principleapocynin, and a yellow glucoside, apocynein; and apocynamarin, or cynotoxin, or cymarin, all of which resemble digitalis glucosides in action. Preparations.-1. Specific M... / ...may be looked for. Under these circumstances we have removed enormous dropsical swellings with it, giving quick relief from dyspnea and1
   The root of Apocynum cannabinum, Linné (Nat. Ord. Apocynaceae) gathered in autumn after the leaves and fruit have matured. Grows throughout the... / ...uents.A resinous principleapocynin, and a yellow glucoside, apocynein; and apocynamarin, or cynotoxin, or cymarin, all of which resemble digitalis glucosides in action. Preparations.-1. Specific M... / ...may be looked for. Under these circumstances we have removed enormous dropsical swellings with it, giving quick relief from dyspnea and1
BAPTISIA
   ...America. Common Names: Wild Indigo, Indigo Weed. Principal Constituents.A poisonous alkaloid baptitoxine (baptisine); two glucosides, baptisin, non-poisonous, and baptin, laxative and cathartic; and......lucosides, baptisin, non-poisonous, and baptin, laxative and cathartic; and a yellowish resin. Baptitoxine is identical with cystisine, ulexine, and sophorine, toxic principles found in other active p......imulate the intestinal glands to secrete more freely and probably increases hepatic secretion. Baptitoxine is said to quicken the breathing and accelerate and strengthen the heart-beat; but in toxic d...1
   ...America. Common Names: Wild Indigo, Indigo Weed. Principal Constituents.A poisonous alkaloid baptitoxine (baptisine); two glucosides, baptisin, non-poisonous, and baptin, laxative and cathartic; and......lucosides, baptisin, non-poisonous, and baptin, laxative and cathartic; and a yellowish resin. Baptitoxine is identical with cystisine, ulexine, and sophorine, toxic principles found in other active p......imulate the intestinal glands to secrete more freely and probably increases hepatic secretion. Baptitoxine is said to quicken the breathing and accelerate and strengthen the heart-beat; but in toxic d...1
COCCULUS
   The seeds of Anamirta panniculata, Colebrooke (Nat. Ord. Menispermaceae.)... / ... Common Names: Fishberries, Indian Berries. Synonym: Cocculus Indicus. Principal Constituent.Picrotoxin, a neutral and extremely poisonous principle. Preparation.Unguentum Cocculi, Ointment of Co... / ...to stupefy fish, so as to readily catch them, and it is asserted to be in use among brewers to add bitterness to beer and other malt beverages.1
   The seeds of Anamirta panniculata, Colebrooke (Nat. Ord. Menispermaceae.)... / ... Common Names: Fishberries, Indian Berries. Synonym: Cocculus Indicus. Principal Constituent.Picrotoxin, a neutral and extremely poisonous principle. Preparation.Unguentum Cocculi, Ointment of Co... / ...to stupefy fish, so as to readily catch them, and it is asserted to be in use among brewers to add bitterness to beer and other malt beverages.1
DIGITALIS
   ...1 to 2 grains. Common Names: Foxglove, Purple Foxglove. Principal Constituents.The glucosides digitoxin (very toxic and cumulative), digitalin, digitalein, digitonin, and digitin (inert); digitalic ......incture of Digitalis (10 per cent of drug). Dose, 1 to 10 drops.Doses of Digitalis Glucosides:Digitoxin, 1/300 to 1/64 grain; digitalin (crystallizable), 1/300 to 1/100 grain, (amorphous and German)...1
   ...1 to 2 grains. Common Names: Foxglove, Purple Foxglove. Principal Constituents.The glucosides digitoxin (very toxic and cumulative), digitalin, digitalein, digitonin, and digitin (inert); digitalic ......incture of Digitalis (10 per cent of drug). Dose, 1 to 10 drops.Doses of Digitalis Glucosides:Digitoxin, 1/300 to 1/64 grain; digitalin (crystallizable), 1/300 to 1/100 grain, (amorphous and German)...1
KALMIA
   The leaves of Kalmia latifolia, Linné (Nat. Ord. Ericaceae). A beautiful shrub of mountains and damp situations in the United States. Common... / ...urel, Sheep Laurel, Lambkill, etc. Principal Constituents.-A neutral, poisonous principle, andromedotoxin (C31H51O10), arbutin, resin, and tannin. Preparation.Specific Medicine Kalmia. Dose, 1 to 20... / ...associated with a syphilitic taint. Kalmia has never obtained a very important place in medicine, though it possesses strongly toxic properties.1
   The leaves of Kalmia latifolia, Linné (Nat. Ord. Ericaceae). A beautiful shrub of mountains and damp situations in the United States. Common... / ...urel, Sheep Laurel, Lambkill, etc. Principal Constituents.-A neutral, poisonous principle, andromedotoxin (C31H51O10), arbutin, resin, and tannin. Preparation.Specific Medicine Kalmia. Dose, 1 to 20... / ...associated with a syphilitic taint. Kalmia has never obtained a very important place in medicine, though it possesses strongly toxic properties.1
PODOPHYLLUM
   ...nstituents.Resin of podophyllum (see below) and podophyllic acid, a coloring substance; podophyllotoxin, the purgative principle of the resin exists free in the rhizome. Preparations.1. Specific......oluble in alcohol, chloroform and ether. It consists chiefly of the purgative principle podophyllotoxin mixed with podophyllic acid (80 per cent), other minor resins, and a yellow, coloring body, po...1
   ...nstituents.Resin of podophyllum (see below) and podophyllic acid, a coloring substance; podophyllotoxin, the purgative principle of the resin exists free in the rhizome. Preparations.1. Specific......oluble in alcohol, chloroform and ether. It consists chiefly of the purgative principle podophyllotoxin mixed with podophyllic acid (80 per cent), other minor resins, and a yellow, coloring body, po...1
SCILLASCILL
   The inner, fleshy scales of the bulb of the white variety of Urginea maritima (Linné), Baker (Nat. Ord. Liliaceae), cut into fragments and... / ...s; average, 1 1/2 grains. Common Names: Squill, Squills, Sea Onion. Principal Constitutents.Scillitoxin, the most active principle, insoluble in water, soluble in alcohol, and a heart poison; scilli... / ...normal equilibrium in the bronchial mucosa. When fever is absent and the sputum scanty and tenacious, the following is useful: Rx Syr. Sci1
   The inner, fleshy scales of the bulb of the white variety of Urginea maritima (Linné), Baker (Nat. Ord. Liliaceae), cut into fragments and... / ...s; average, 1 1/2 grains. Common Names: Squill, Squills, Sea Onion. Principal Constitutents.Scillitoxin, the most active principle, insoluble in water, soluble in alcohol, and a heart poison; scilli... / ...normal equilibrium in the bronchial mucosa. When fever is absent and the sputum scanty and tenacious, the following is useful: Rx Syr. Sci1
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.
Physician's Materia Medica on Toxin
COCCULUS
   The fruit of ANAMIRTA COCeUurs. Wight and Arn. Dangerous ly poisonous, in small doses antispasmodic; used chiefly as a parasiti cide. Active principle Picrotoxin q. v.2
   The fruit of ANAMIRTA COCeUurs. Wight and Arn. Dangerous ly poisonous, in small doses antispasmodic; used chiefly as a parasiti cide. Active principle Picrotoxin q. v.2
MANDRAKEMANDR
   The rhizome of PODOPHYLLUM PELTATUM, Lin. Cholagogue, laxative or purgative according to dose. Much used as a laxative in chronic constipation and as a hepatic stimulant, g.'ncr;ll1y in the form of the resin, commonly called podophyllin. The active principle is belived to be Podophyllotoxin, q. v.2
   The rhizome of PODOPHYLLUM PELTATUM, Lin. Cholagogue, laxative or purgative according to dose. Much used as a laxative in chronic constipation and as a hepatic stimulant, g.'ncr;ll1y in the form of the resin, commonly called podophyllin. The active principle is belived to be Podophyllotoxin, q. v.2
PICROTOXIN
   A neutral principle obtained from the seeds of ANAMIRTA COCCULUS, (L-) Wight & Arn. (Cocculus Indicus). In small doses,-it is an efficient remedy for night sweats. Dose, 0.0006 to 0.0025 Grm. (1-100 to 1-25 gr.).2
   A neutral principle obtained from the seeds of ANAMIRTA COCCULUS, (L-) Wight & Arn. (Cocculus Indicus). In small doses,-it is an efficient remedy for night sweats. Dose, 0.0006 to 0.0025 Grm. (1-100 to 1-25 gr.).2
PODOPHYLLOTOXIN
   The most active constituent of MANDRAKE, q. v. Dose, 0.004 to 0.030 Grm. (1-16 to 1/2 gr.). about one half that of Podophyllin.2
   The most active constituent of MANDRAKE, q. v. Dose, 0.004 to 0.030 Grm. (1-16 to 1/2 gr.). about one half that of Podophyllin.2
TONIC PILOCARPINE COMPOUND
   A combination in which the powerful secernant action of Pilocarpine is secured without the depressing effects commonly produced by that remedy. A most eflicient agent in the treatment of anasarca and ascites. Each fluidrachm contains; Pilocarpine Hydrochloride, 1-32 gr.; Strychnine Sulphate, 1-64 gr.; Digitoxin, 1-500 gr.; Sparteine Sulphate. 1/8 gr.2
   A combination in which the powerful secernant action of Pilocarpine is secured without the depressing effects commonly produced by that remedy. A most eflicient agent in the treatment of anasarca and ascites. Each fluidrachm contains; Pilocarpine Hydrochloride, 1-32 gr.; Strychnine Sulphate, 1-64 gr.; Digitoxin, 1-500 gr.; Sparteine Sulphate. 1/8 gr.2
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.
Physician's Therapeutics Memoranda on Toxin
DIPHTHERIA AND MEMBRANOUS CROUP
   Isolate the patient and watch carefully all children who may have been exposed. In every case use Diphtheria... / Isolate the patient and watch carefully all children who may have been exposed. In every case use Diphtheria Antitoxin if at hand and use it promptly. As local application, peroxide of hydrogen is most satisfactory. Loefl1er’s solution (menthol, 100 grs. dissol... / ...nourishing food such as peptonized milk (given per rectum if swallowing is im possible).2
   Isolate the patient and watch carefully all children who may have been exposed. In every case use Diphtheria... / Isolate the patient and watch carefully all children who may have been exposed. In every case use Diphtheria Antitoxin if at hand and use it promptly. As local application, peroxide of hydrogen is most satisfactory. Loefl1er’s solution (menthol, 100 grs. dissol... / ...nourishing food such as peptonized milk (given per rectum if swallowing is im possible).2
TETANUS
   Tetanus antitoxin should be administered at once, and convul sions combated by inhalations of chloroform or by chloral combined with potassium bromide (see Bromanodyne, Part I). Other remedies are cocaine or a combination of this with morphine and atropine, hypodermatically; Fowler’s solution; calabar bean; pilocarpine (the last to eliminate the toxin).2
   Tetanus antitoxin should be administered at once, and convul sions combated by inhalations of chloroform or by chloral combined with potassium bromide (see Bromanodyne, Part I). Other remedies are cocaine or a combination of this with morphine and atropine, hypodermatically; Fowler’s solution; calabar bean; pilocarpine (the last to eliminate the toxin).2
References
1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.