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Dapt FDA Approved Drugs
CUBICIN [DaptomycinC72H101N17O26]
RX
- 500mg/vial (intravenous powder)
Cubist Pharms LlcSep 12, 2003
- Treatment of the following infections: complicated skin and skin structure infections and staphylococcus aureus bloodstream infections (bacteremia) including those with right-sided infective endocarditis.
CUBICIN RF [DaptomycinC72H101N17O26]
RX
- 500mg/vial (intravenous powder)
Cubist Pharms LlcJul 6, 2016
- Treatment of the following infections: complicated skin and skin structure infections and staphylococcus aureus bloodstream infections (bacteremia) including those with right-sided infective endocarditis.
DAPTOMYCIN [DaptomycinC72H101N17O26]
RX
- 500mg/vial (intravenous powder)
Crane Pharms LlcJun 15, 2016
Hospira IncSep 12, 2014
Teva ParenteralMar 25, 2016
Hospira IncSep 12, 2014
Teva ParenteralMar 25, 2016
RYDAPT [MidostaurinC35H30N4O4]
RX
- 25mg (oral capsule)
Novartis Pharms CorpApr 28, 2017
- Treatment of adult patients with aggressive systemic mastocytosis (asm), systemic mastocytosis with associated hematological neoplasm (sm-ahn), or mast cell leukemia (mcl).
- Treatment of adult patients with newly diagnosed acute myeloid leukemia (aml) who are flt3 mutation-positive, in combination with standard cytarabine and daunorubicin induction and cytarabine consolidation chemotherapy.
WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.
Felter's Materia Medica on Dapt
APOCYNUM CANNABINUM
The root of Apocynum cannabinum, Linné (Nat. Ord. Apocynaceae) gathered in autumn after the leaves and fruit have matured. Grows throughout the... / ...if there were circulatory obstruction or active fever. The only apparent exception, in which it is adapted to active conditions, is that reported by Webster of its efficacy in active inflammation of t... / ...may be looked for. Under these circumstances we have removed enormous dropsical swellings with it, giving quick relief from dyspnea and1
The root of Apocynum cannabinum, Linné (Nat. Ord. Apocynaceae) gathered in autumn after the leaves and fruit have matured. Grows throughout the... / ...if there were circulatory obstruction or active fever. The only apparent exception, in which it is adapted to active conditions, is that reported by Webster of its efficacy in active inflammation of t... / ...may be looked for. Under these circumstances we have removed enormous dropsical swellings with it, giving quick relief from dyspnea and1
ASAFOETIDA (Ferula fetida)
... antispasmodic, and is a very useful nervine for functional spasmodic affections. It is especially adapted to neurotic individuals subject to hysterical or emotional attacks, usually attended by flatu......he nervous irritability of dentition. On the whole asafetida is a simple and efficient remedy best adapted to disorders with nervous depression, more or less feebleness, and particularly if associated...1
... antispasmodic, and is a very useful nervine for functional spasmodic affections. It is especially adapted to neurotic individuals subject to hysterical or emotional attacks, usually attended by flatu......he nervous irritability of dentition. On the whole asafetida is a simple and efficient remedy best adapted to disorders with nervous depression, more or less feebleness, and particularly if associated...1
ASCLEPIAS TUBEROSA
...y case it will enhance the value of these agents. In pneumonia and in bronchitis asclepias is best adapted to the acute stage, where the lesions seem to be extensive, taking in a large area of the par......of the parenchyma of the lung or the bronchial structures and the mucosa. Webster declares it best adapted to control vascular disturbances in the area supplied by the bronchial arteries, and suggests...1
...y case it will enhance the value of these agents. In pneumonia and in bronchitis asclepias is best adapted to the acute stage, where the lesions seem to be extensive, taking in a large area of the par......of the parenchyma of the lung or the bronchial structures and the mucosa. Webster declares it best adapted to control vascular disturbances in the area supplied by the bronchial arteries, and suggests...1
CASCARA SAGRADA
The dried bark of Rhamnus Purshiana, De Candolle (Nat. Ord. Rhamnaceae). A shrub of Northern Idaho and the Pacific coast. Dose, 5 to 30... / ... decreased from day to day often with the result of completely curing the constipation. Cascara is adapted to cases of atony of the intestines. When other simple ailments depend upon constipation they... / ...Dose: One half to one teaspoonful at bedtime. If a more profound action is desired a half drachm of Specific Medicine Podophyllum may be added.1
The dried bark of Rhamnus Purshiana, De Candolle (Nat. Ord. Rhamnaceae). A shrub of Northern Idaho and the Pacific coast. Dose, 5 to 30... / ... decreased from day to day often with the result of completely curing the constipation. Cascara is adapted to cases of atony of the intestines. When other simple ailments depend upon constipation they... / ...Dose: One half to one teaspoonful at bedtime. If a more profound action is desired a half drachm of Specific Medicine Podophyllum may be added.1
CAULOPHYLLUM
The rhizome and roots of Caulophyllum thalictroides (Linné, Michaux (Nat. Ord. Berberidaceae). In rich woods in the eastern half of the United... / ...eproductive organs of women, overcoming pain and tenderness in debilitated subjects. It seems best adapted to uterine debility arising from chronic inflammatory conditions. In many respects it resembl... / ...of strength and rapid involution of the womb following labor. The dose of the syrup is from 2 fluidrachms to 1/2 fluidounce, 2 or 3 times a day.1
The rhizome and roots of Caulophyllum thalictroides (Linné, Michaux (Nat. Ord. Berberidaceae). In rich woods in the eastern half of the United... / ...eproductive organs of women, overcoming pain and tenderness in debilitated subjects. It seems best adapted to uterine debility arising from chronic inflammatory conditions. In many respects it resembl... / ...of strength and rapid involution of the womb following labor. The dose of the syrup is from 2 fluidrachms to 1/2 fluidounce, 2 or 3 times a day.1
CONIUM
...fficient except in doses which would be equally as dangerous as the disorder itself . It is better adapted to control the excessive movements of hysteria and mania, but in the former having little eff......ts. As the terminals of the sensory and motor nerves are directly affected by the drug, it is best adapted to peripheral pain with excessive mobility. Thus it relieves spasmodic neuralgia, neuralgia f...1
...fficient except in doses which would be equally as dangerous as the disorder itself . It is better adapted to control the excessive movements of hysteria and mania, but in the former having little eff......ts. As the terminals of the sensory and motor nerves are directly affected by the drug, it is best adapted to peripheral pain with excessive mobility. Thus it relieves spasmodic neuralgia, neuralgia f...1
COPAIBACOOF2
An oleoresin derived from species of Copaiba growing in South America. Dose, 5 to 30 drops. Description.A viscid, pale-yellow or brownish-yellow... / ...aluable by injection than when used internally. The foregoing treatment is Lockes method, and is adapted to otherwise unconquerable cases. Most cases of gonorrhea are now readily cured by more moder...1
An oleoresin derived from species of Copaiba growing in South America. Dose, 5 to 30 drops. Description.A viscid, pale-yellow or brownish-yellow... / ...aluable by injection than when used internally. The foregoing treatment is Lockes method, and is adapted to otherwise unconquerable cases. Most cases of gonorrhea are now readily cured by more moder...1
CORNUSCOAC
The bark and root-bark of Cornus florida, Linné. (Nat. Ord. Cornaceae.) A beautiful flowering tree of the United States. Dose, 5 to 60... / ...type; and it is said to be useful in headache from quinine, pyrosis, and general exhaustion. It is adapted to cases with feeble, relaxed tissues, with weak pulse and subnormal temperature. It has been...1
The bark and root-bark of Cornus florida, Linné. (Nat. Ord. Cornaceae.) A beautiful flowering tree of the United States. Dose, 5 to 60... / ...type; and it is said to be useful in headache from quinine, pyrosis, and general exhaustion. It is adapted to cases with feeble, relaxed tissues, with weak pulse and subnormal temperature. It has been...1
DIOSCOREA
...euralgia and spasmodic dysmenorrhea sometimes yield quickly to it. In all disorders it seems best adapted to irritable and excitable conditions and is less efficient when due to atony. Though dioscor......bably without power to relieve. Morphine is a better relaxant and is anodyne. Dioscorea seems best adapted to paroxysmal pain due to contraction of the nonstriated musculature of tubular organs, when ...1
...euralgia and spasmodic dysmenorrhea sometimes yield quickly to it. In all disorders it seems best adapted to irritable and excitable conditions and is less efficient when due to atony. Though dioscor......bably without power to relieve. Morphine is a better relaxant and is anodyne. Dioscorea seems best adapted to paroxysmal pain due to contraction of the nonstriated musculature of tubular organs, when ...1
EUPATORIUM PURPUREUM
The root of Eupatorium purpureum, Linné (Nat. Ord. Compositae). Low meadows and woods of the United States. Dose, 5 to 60 grains. Common Names:... / ...n of the urinary passages. For this purpose it is one of the most satisfactory of medicines. It is adapted to cases in which there is constant urging to pass urine, accompanied by a sense of obstructi... / ...acts well with the special sedatives, and if fever is present or the skin is hot, dry, and constricted it may be given with aconite or gelsemium.1
The root of Eupatorium purpureum, Linné (Nat. Ord. Compositae). Low meadows and woods of the United States. Dose, 5 to 60 grains. Common Names:... / ...n of the urinary passages. For this purpose it is one of the most satisfactory of medicines. It is adapted to cases in which there is constant urging to pass urine, accompanied by a sense of obstructi... / ...acts well with the special sedatives, and if fever is present or the skin is hot, dry, and constricted it may be given with aconite or gelsemium.1
GERANIUMGERAN
The rhizome of Geranium maculatum, Linné (Nat. Ord. Geraniaceae). Common in the rich soils of woods and low grounds in the United States. Dose, 5... / ...e and chronic bowel disorders when the evacuations are abundant and debilitating. It is especially adapted to relaxation of the mucosa following inflammation. For the summer diarrheas of older childre... / ...correct excessive acidity, check hemorrhage, and relieve pain; sometimes healing appears to progress rapidly under their influence.1
The rhizome of Geranium maculatum, Linné (Nat. Ord. Geraniaceae). Common in the rich soils of woods and low grounds in the United States. Dose, 5... / ...e and chronic bowel disorders when the evacuations are abundant and debilitating. It is especially adapted to relaxation of the mucosa following inflammation. For the summer diarrheas of older childre... / ...correct excessive acidity, check hemorrhage, and relieve pain; sometimes healing appears to progress rapidly under their influence.1
GUAIACUM
The resin of the wood of Guaiacum officinale, Linné, or of Guaiacum sanctum, Linné (Nat. Ord. Zygophyllaceae). West Indian trees. Dose, 5 to 30... / ...hile seemingly indicated in active conditions in sore throat and in chronic rheumatism, it is best adapted to passive conditions-cold hands and feet, feeble circulation, and vital depression. In gener... / ...dilution of specific medicine, mixed with syrup and water. Stronger preparations than this diluted tincture precipitate heavily.1
The resin of the wood of Guaiacum officinale, Linné, or of Guaiacum sanctum, Linné (Nat. Ord. Zygophyllaceae). West Indian trees. Dose, 5 to 30... / ...hile seemingly indicated in active conditions in sore throat and in chronic rheumatism, it is best adapted to passive conditions-cold hands and feet, feeble circulation, and vital depression. In gener... / ...dilution of specific medicine, mixed with syrup and water. Stronger preparations than this diluted tincture precipitate heavily.1
HAMAMELIS
The leaves, bark and twigs of Hamamelis virginiana, Linné (Nat. Ord. Hamamelidaceae), collected in the autumn. Common in the United States.... / ...es and which renders their occurrence easy. It is of less value in hemoptysis than lycopus, and is adapted to such cases as are benefited by geranium and erigeron. Hamamelis is a decidedly useful reme... / ...of the uterus, with soft and flabby cervi1
The leaves, bark and twigs of Hamamelis virginiana, Linné (Nat. Ord. Hamamelidaceae), collected in the autumn. Common in the United States.... / ...es and which renders their occurrence easy. It is of less value in hemoptysis than lycopus, and is adapted to such cases as are benefited by geranium and erigeron. Hamamelis is a decidedly useful reme... / ...of the uterus, with soft and flabby cervi1
HELONIASHELON
The rhizome of Chamaelirium luteum, Gray (Helonias dioica, Pursh)-(Nat. Ord. Liliaceae). Abundant in woodlands, meadows, and wet places in some... / ...ge. (For relation to Aletris, compare Aletris.) Helonias is a valuable uterine tonic, specifically adapted to uterine weakness in which relaxation of tissue is so great as to give the sensation of dow... / ...It is also said to relieve the nausea and vomiting of pregnancy, to prevent miscarriages, and to correct gastric complications of albuminuria.1
The rhizome of Chamaelirium luteum, Gray (Helonias dioica, Pursh)-(Nat. Ord. Liliaceae). Abundant in woodlands, meadows, and wet places in some... / ...ge. (For relation to Aletris, compare Aletris.) Helonias is a valuable uterine tonic, specifically adapted to uterine weakness in which relaxation of tissue is so great as to give the sensation of dow... / ...It is also said to relieve the nausea and vomiting of pregnancy, to prevent miscarriages, and to correct gastric complications of albuminuria.1
HYDRASTISHYDRA2
The dried rhizome and roots of Hydrastis canadensis, Linné (Nat. Ord. Ranunculaceae) United States and Canada in rich, shady woods. (Chiefly... / ...ds. Hydrastis is universally admitted to be a most valuable topical agent in gonorrhea. It is best adapted after the first and acute stage has passed, though it is not contraindicated at any time duri...1
The dried rhizome and roots of Hydrastis canadensis, Linné (Nat. Ord. Ranunculaceae) United States and Canada in rich, shady woods. (Chiefly... / ...ds. Hydrastis is universally admitted to be a most valuable topical agent in gonorrhea. It is best adapted after the first and acute stage has passed, though it is not contraindicated at any time duri...1
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.
Physician's Materia Medica on Dapt
BROMOFORM BRONCHIAL ANODYNE
Each fluidrachm contains; Bromoform, 1 drop; Ipecac, 1-16 gr.; Ammonium Bromide, 3 grs.; Benzoin, % gr. A bronchial sedative particularly adapted to the requirements of children; especially eflicacious in infantile croup (not membranous) and in whooping cough. Although intended particularly for children, it will be found useful also in relieving troublesome irritative and spasmodic cough in adults. Dose for a child ten years old, 4 c. c. (a fluidrachm), to be repeated every two hours. In whoopin2
Each fluidrachm contains; Bromoform, 1 drop; Ipecac, 1-16 gr.; Ammonium Bromide, 3 grs.; Benzoin, % gr. A bronchial sedative particularly adapted to the requirements of children; especially eflicacious in infantile croup (not membranous) and in whooping cough. Although intended particularly for children, it will be found useful also in relieving troublesome irritative and spasmodic cough in adults. Dose for a child ten years old, 4 c. c. (a fluidrachm), to be repeated every two hours. In whoopin2
NUTRIENT PEPTONES WITH CREOSOTE
This preparation combines with the peptonized nitrogenous con stituents of beef, milk and cereal grains as much Creosote and Guaia col as can be rendered at all palatable. It constitutes thus a highly concentrated, predigested food, having also the stimulant properties of the wine which forms the vehicle, and a powerful bactericidal action due to the creosote present. The combination is one admira bly adapted to meet the indications in a wasting disease like phthisis, and experience has shown th2
This preparation combines with the peptonized nitrogenous con stituents of beef, milk and cereal grains as much Creosote and Guaia col as can be rendered at all palatable. It constitutes thus a highly concentrated, predigested food, having also the stimulant properties of the wine which forms the vehicle, and a powerful bactericidal action due to the creosote present. The combination is one admira bly adapted to meet the indications in a wasting disease like phthisis, and experience has shown th2
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.
Physician's Therapeutics Memoranda on Dapt
BRONCHITIS
In the incipient stage, quinine with a little Dover powder and a laxative may ward off the... / ...fever, application to chest of Phenol Camphor; ipecac and potassium salts to promote secretion; inhalations of steam or of moisture-laden air. Later adapt remedies to condition of patient. As expectorants use ammonium chloride, ammonium carbonate, lobelia, senega, etc., combining these with henbane,...2
In the incipient stage, quinine with a little Dover powder and a laxative may ward off the... / ...fever, application to chest of Phenol Camphor; ipecac and potassium salts to promote secretion; inhalations of steam or of moisture-laden air. Later adapt remedies to condition of patient. As expectorants use ammonium chloride, ammonium carbonate, lobelia, senega, etc., combining these with henbane,...2
HEART DISEASE
In organic diseases of the heart. remedies must be adapted to symptoms presented. Digitalis and similar agents are to be used when increase of... / In organic diseases of the heart. remedies must be adapted to symptoms presented. Digitalis and similar agents are to be used when increase of blood pressure is desired; strophanthus when increas ed pre... / ...general tonics are indicated, particularly nux vomica and iron. In cardiac failure, use diffusible stimulants, ammonia, ether and alcohol.2
In organic diseases of the heart. remedies must be adapted to symptoms presented. Digitalis and similar agents are to be used when increase of... / In organic diseases of the heart. remedies must be adapted to symptoms presented. Digitalis and similar agents are to be used when increase of blood pressure is desired; strophanthus when increas ed pre... / ...general tonics are indicated, particularly nux vomica and iron. In cardiac failure, use diffusible stimulants, ammonia, ether and alcohol.2
References
1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.