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Ledgend of Medicine







discontinued


Onfi FDA Approved Drugs

ALDARA [ImiquimodC14H16N4]
RX
-
5% (topical cream)
MedicisFeb 27, 1997
  • Treatment of biopsy-confirmed, primary superficial basal cell carcinoma (sbcc).
  • Works through the induction of interferon and other cytokines.
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

AUGMENTIN XR [AmoxicillinC16H19N3O5S3H2O : Clavulanate PotassiumC8H8NO5K]
RX
-
1gm : eq 62.5mg base (oral tablet, extended release)
Dr Reddys Labs IncSep 25, 2002
  • Mgt specific bacterial infections. treatment pts w/ community acquired pneumonia or bacterial sinusitis due to confirmed, or suspected b-lactamase producing pathogens & s. pneumoniae with reduced susceptibility to penicillin (mic=2mc/ml).
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

EXONDYS 51 [Eteplirsen]
RX
-
100mg/2ml (50mg/ml) (iv (infusion) solution)
500mg/10ml (50mg/ml) (iv (infusion) solution)
Sarepta Theraps IncSep 19, 2016
  • (i)treatment of duchenne muscular dystrophy; (ii)restoring/increasing functional dystrophin protein; or (iii) inducing skipping; each of (i)-(iii) in patients having a confirmed mutation of the dmd gene that is amenable to exon 51 skipping.
  • Restoring an mrna reading frame to induce dystrophin protein production in patients having a mutation of the dmd gene that is amenable to exon 51 skipping.
  • Treatment of duchenne muscular dystrophy in patients having a mutation of the dmd gene that is amenable to exon 51 skipping.
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

ONFI [ClobazamC16H13ClN2O2]
RX
-
10mg (oral tablet)
2.5mg/ml (oral suspension)
20mg (oral tablet)
Lundbeck Pharms LlcOct 21, 2011
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

TAFINLAR [Dabrafenib MesylateC23H20F3N5O2S2CH4O3S]
RX
-
eq 50mg base (oral capsule)
eq 75mg base (oral capsule)
Novartis Pharms CorpMay 29, 2013
  • Tafinlar in combination with trametinib for the treatment of patients with unresectable or metastatic melanoma.
  • Treatment of melanoma.
  • Treatment of patients with unresectable or metastatic melanoma with braf v600e mutations after confirming the presence of braf v600e mutation.
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.


WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Felter's Materia Medica on Onfi

BRYONIA
   The root of Bryonia dioica, Jacquin, and Bryonia alba, Linné (Nat. Ord. Cucurbitaceae.) Europe. Common Names: Bryony, Bastard Turnip, Devil's... / ...m. In la grippe, it is one of the best of remedies, both for the cough and the debility. We use it confidently in pneumonia to control pain, when present; but above all, to allay the harsh, harassing ... / ...its origin in irritation or erethism. Tensive or sharp pains are almost always present, and the secretion, if there is any, is small in quantit1

CANTHARIS
   The dried beetles, Cantharis vesicatoria (Linné), De Geer. (Ord. Coleoptera.) Southern Europe. Dose, 1 grain. Common Name: Spanish Fly; Synonym:... / ...tharides is the smallest amount known to have produced death. Cases of poisoning are almost always confined to those who take cantharis to produce abortion. There is no known chemical or physiologic a...1

CHELIDONIUM
   The whole plant of Chelidonium majus, Linné (Nat. Ord. Papaveraceae). Europe naturalized in waste places in the United States. Dose, 1 to 60... / ...mboge. Though reputed to be of some value locally as a stimulant and vulnerary, its present use is confined almost wholly to disorders hinging on imperfect or faulty hepatic function. It also appears... / ...they are proportionately relieved by the action of chelidonium upon the latter. The greatest drawback to chelidonium is its horribly nasty taste.1

CHIMAPHILA
   The leaves or whole plant of Chimaphila umbellata (Linné, Nuttall. (Nat. Ord. Ericaceae.) North temperate region of the Northern Hemispheres, and... / ...ugh the cases were but incipient cases of albuminuria. Not much hope should be expected from it in confirmed nephritis. It is often useful in chronic prostatic irritation and in some cases of prostati... / ...the disappearance of sugar in glycosuria. Chimaphila is a neglected remedy that may well take the place of other agents of questionable safety.1

FRANCISCEA
   The root and stem of Brunfelsia (Franciscea) uniflora, Pohl (Nat. Ord. Solanaceae). A tropical American shrub. Common Names: Manaca, Vegetable... / ...is. It is capable of producing gastro-enteritis and death. Manaca has been proposed for rheumatism confined more to the muscles and tendons than to the articular forms, acting best when there is dull,...1

GRINDELIA
   The dried leaves and flowering tops of one or several species of Grindelia—as Grindelia camporum, Greene; or Grindelia squarrosa (Pursh), Dunal.... / ...alignant ulceration, as epitheliomata of the mucosa and the skin. This is claiming much and awaits confirmation from the experience of others. The leaves of grindelia, smoked alone or mixed with stram... / ...over the spleen, sallow skin, debility and indigestion, with gastric distress. The bitter taste of grindelia is best disguised by chloroform.1

PHYSOSTIGMAPHYSO4
   ...traction takes place, even though atropine has previously produced dilatation; and the effects are confined only to the eye so treated. Poisonous doses increase the foregoing symptoms, with the additi......s increase the foregoing symptoms, with the addition of muscular tremors or fibrillary twitchings (confined only to portions of the muscle), the reflexes are abolished, respiration and circulation are...1

SALIX NIGRA
   The bark and aments of Salix nigra, Linné (Nat. Ord. Salicaceae); United States, particularly along streams in New York and Pennsylvania. Common... / ...s possessing antiseptic and detergent properties, the use of the aments is of more recent date and confined almost wholly to the generative organs. To be of value, however, only the freshly gathered a... / ...the reproductive tract when pollutions are the result of sexual intemperance, libidinous thoughts by day, and lascivious dreams by night.1

STICTA
   The lichen Sticta Pulmonaria, Linné (Nat. Ord. Lichenes). Found upon tree trunks and rocks in England and the eastern United States, mostly in... / ...ctival hyperaemia or inflammation. Action and Therapy.—Sticta relieves pain and muscular soreness confined chiefly to the neck, head, and chest, and irritation in parts supplied by the vagus. Thus i... / ...relieved by it simulates lameness, is increased by taking a deep breath, and feels like that arising from a bruise or muscular overexertion.1


WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Physician's Materia Medica on Onfi

AMMONIA
   The medicinal preparation (Water of Ammonia) is a solution in water of the gas, Ammonia. Powerful irritant, rubefacient; much used in stimulating liniments, which should never be confined under an impervious covering unless blistering is desired. Internally a powerful stimulant, the effect passing off, however, quickly. It is antacid, but the carbonate is to be preferred for this use. Dilute solutions give relief for insect stings. Dose, 0.06 to 1.0 c. c. (1 to 15 m), highly diluted.2


References

1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.