What is alpha-1 antitrypsin deficiency (AAT deficiency)?
Alpha-1 antitrypsin deficiency (AAT deficiency, or AATD) is an inherited condition that raises your risk for lung and liver disease. If you have this condition, your body doesn't make enough alpha-1 antitrypsin (AAT).
AAT is made by your liver. It helps protect your lungs from inflammation and irritating substances you might breathe in, such as smoke. If your liver doesn't make enough AAT, your lungs may be more easily damaged from smoking, pollution, or dust from the environment. This can lead to a serious lung condition called chronic obstructive pulmonary disease (COPD). AAT deficiency may also cause a liver disease called cirrhosis. This is more common in children who have AAT deficiency.
What causes alpha-1 antitrypsin deficiency (AAT deficiency)?
AAT deficiency is a genetic disorder. That means it's caused by changes in your genes, which may also be called gene variants or mutations.
Your genes carry information that controls what you look like and how your body works. AAT deficiency is caused by changes in the SERPINA1 gene, which carries instructions for making the AAT protein. These gene changes are inherited from your parents, so AAT deficiency tends to run in families:
If you have two mutated copies of the gene, it means you have a condition called AAT deficiency. People with this disorder have a higher risk of getting lung disease or liver damage before the age of 45.
If you have one mutated copy of the gene, you are a carrier of AAT deficiency. In these cases, this means you are at slightly higher risk of developing lung disease, especially if you have other risk factors, such as being a smoker. You could still pass the mutated gene on to your children.
There are a few gene changes that cause AAT deficiency. These gene changes can:
Decrease the amount of AAT protein your liver makes.
Prevent your liver from making any AAT.
Affect the shape of the AAT protein so that it can't move out of your liver to protect your lungs. Over time, AAT builds up in your liver and causes damage.
What are the symptoms of alpha-1 antitrypsin deficiency (AAT deficiency)?
Some people who have AAT deficiency do not have any symptoms. For those who do, symptoms usually appear in people between 20 and 50 years old. These symptoms may include:
Wheezing
Shortness of breath, especially after exercise
Chronic cough with phlegm (mucus)
Repeated respiratory infections such as colds and the flu
Chest pain
Fatigue
Faster-than-normal heartbeat when you stand up
Vision problems
Losing weight without trying
Some people who have AAT deficiency may have liver damage. Signs of liver damage include jaundice (a condition that causes your skin and eyes to turn yellow) and swelling in your legs.
Rarely, AAT deficiency can cause skin problems, such as painful lumps or patches.
How is alpha-1 antitrypsin deficiency (AAT deficiency) diagnosed?
Your health care provider may test you for AAT deficiency if you have:
Symptoms of AAT deficiency
A condition that could be related to AAT deficiency
Relatives who have AAT deficiency
Relatives who have a lung or liver disease that could be related to AAT deficiency
AAT deficiency in babies often affects the liver. Your baby may need AAT testing if he or she has signs of liver disease such as jaundice or abnormal liver enzyme tests.
A blood test can check the level of AAT protein in your blood. If the level is lower than normal, it is likely that you have AAT deficiency.
A genetic test is the most certain way to check for AAT deficiency and should be done to confirm the results of the blood test. There are two types of genetic tests:
A genotype test looks for the more common types of gene changes that can cause AAT deficiency.
A phenotype test checks for changes in the AAT protein that change how it would normally work.
If your lungs are affected, you may also have lung function tests to see how well your lungs are working.
What are the treatments for alpha-1 antitrypsin deficiency (AAT deficiency)?
There is no cure for AAT deficiency, but there are treatments to help with the symptoms and slow the lung damage it causes. Treatment options may include:
Inhaled medicines to help you breathe better.
Pulmonary rehabilitation.
Oxygen therapy.
Augmentation therapy, which is a lifelong treatment. It raises the levels of the AAT protein in your lungs, using ATT protein taken from the blood of donors. It helps slow down lung damage. It cannot prevent liver damage.
Lung surgery or a lung transplant, if your lungs are severely damaged.
Liver transplant, if your liver is severely damaged.
To help prevent or delay lung damage, it is important to quit smoking (if you smoke) and avoid secondhand smoke, dust, and air pollution. Ask your provider If you need to stop drinking alcohol.
Treatment of advanced hormone receptor positive, her2-negative breast cancer in combination with exemestane after failure of treatment with letrozole or anastrozole.
Treatment of patients with progessive neuroendocrine tumors of pancreatic origin (pnet) that are unresectable, locally advanced or metastatic.
Treatment of patients with tuberous sclerosis complex (tsc) who have subependymal giant cell astrocytoma (sega) that requires therapeutic intervention but cannot be curatively resected..
Treatment of solid excretory system tumors; advanced renal cell carcinoma (rcc), after failure of treatment with sunitinib or sorafenib.
Treatment of patients with tuberous sclerosis complex (tsc) who have subependymal giant cell astrocytoma (sega) that requires therapeutic intervention but cannot be curatively resected..
Method for relieving constipation in a human patient that comprises administering to the patient a dosage unit comprising (i) 24mcg+/- 10% of a drug substance and (ii) a pharmaceutically suitable excipient.
Method for relieving constipation in a patient with opioid-induced constipation that comprises administering to the patient a dosage unit comprising(i)24microg+/- 10% of a drug substance and (ii) a pharmaceutically suitable excipient.
Method for relieving or treating constipation in a human constipated patient.
Method for relieving or treating constipation in a patient with irritable bowel syndrome.
Method for relieving or treating constipation in a patient with opioid-induced constipation.
Method for the long term treatment of chronic constipation in a human subject with irritable bowel syndrome.
Method for the long term treatment of chronic constipation in a human subject.
Method for treating constipation by opening cic channels in a mammalian subject.
Method for treating constipation in a patient with opioid-induced constipation by opening cic channels.
Method for treating irritable bowel syndrome and method for treating abdominal discomfort associated with irritable bowel syndrome.
Method for treating opioid-induced constipation.
Method of relieving or preventing constipation in a human constipated patient.
Method of relieving or preventing constipation in a human patient with opioid-induced constipation.
Method of treating constipation in a patient with irritable bowel syndrome by opening chloride channels (cic).
Method of treating constipation in a patient with irritable bowel syndrome.
Use in relieving or preventing constipation in a human patient with a dosage unit comprising 24microg+/- 10% of a drug substance and a pharmaceutically suitable excipient.
Use in relieving or preventing constipation in a patient with opioid-induced constipation with a dosage unit comprising 24microg +/- 10% of a drug substance and a pharmaceutically suitable excipient.
Management of mild to moderate pain, management of moderate to severe pain as an adjunct to opioid analgesics in a critically ill patient with intravenous ibuprofen in need thereof.
Management of mild to moderate pain, management of moderate to severe pain as an adjunct to opioid analgesics, reduction in fever through anti-inflammatory, analgesic, and antipyretic activity.
Management of mild to moderate pain, management of moderate to severe pain as an adnunct to opioid analgesics, reduction in fever through anti inflammatory, analgesic, and antipyretic activity.
Methods of treating pain, inflammation and/or fever in a critically ill patient with intravenous ibuprofen in need thereof.
Methods of treating pain, inflammation and/or fever with intravenous ibuprofen such that mean arterial blood pressure does not increase the dosage interval.
Replacement therapy for oral carbamazepine in adults with generalized tonic-clonic seizures.
Replacement therapy for oral carbamazepine in adults with mixed seizure patterns that include partial seizures with complex symptomatology, generalized tonic-clonic seizures, or other partial or generalized seizures.
Replacement therapy for oral carbamazepine in adults with partial seizures with complex symptomatology.
A method to accelerate the time to gastrointestinal recovery by administering about 12 mg of alvimopan to the patient from about 30 to 60 minutes prior to surgery.
Accelerating the time to upper and lower gastrointestinal recovery following surgeries that include partial bowel resection with primary anastomosis.
Treating a subject undergoing abdominal surgery by administering alvimopan to accelerate the time to upper and lower gastrointestinal recovery following surgeries that include partial bowel resection with primary anastomosis.
(i)treatment of duchenne muscular dystrophy; (ii)restoring/increasing functional dystrophin protein; or (iii) inducing skipping; each of (i)-(iii) in patients having a confirmed mutation of the dmd gene that is amenable to exon 51 skipping.
Restoring an mrna reading frame to induce dystrophin protein production in patients having a mutation of the dmd gene that is amenable to exon 51 skipping.
Treatment of duchenne muscular dystrophy in patients having a mutation of the dmd gene that is amenable to exon 51 skipping.
Treatment of exocrine pancreatic cancer that has progressed on gemcitabine-based therapy, in combination with 5-fluorouracil and leucovorin.
Treatment of metastatic adenocarcinoma of the pancreas that has progressed on gemcitabine-based therapy, in combination with 5-fluorouracil and leucovorin, in a patient homozygous for the ugt1a1*28 allele.
Treatment of metastatic adenocarcinoma of the pancreas that has progressed on gemcitabine-based therapy, in combination with 5-fluorouracil and leucovorin.
Treatment of pancreatic cancer that has progressed on gemcitabine-based therapy, in combination with 5-fluorouracil and leucovorin.
Method of providing a therapeutically effective and stable median blood plasma level of levodopa.
Treatment of parkinson's disease, post-encephalitic parkinsonism, and parkinsonism that may follow carbon monoxide intoxication or manganese intoxication.
Treatment of parkinson's disease.
Treatment of parkinsonism that may follow carbon monoxide intoxication or manganese intoxication.
Treatment of post-encephalitic parkinsonism, and parkinsonism that may follow carbon monoxide intoxication or manganese intoxication.
A method of treating dyslipidemia and dyslipoproteinemia using a dosage form that can provide an effective amount of fenofibrate to a patient in a fasted state which is at least 90% of the auc amount provided by the dosage form.
Use of ribavirin to increase type 1 cytokine response and suppress type 2 cytokine resp0nse to lymphocytes, including methods that take advantage of such modulation to treat infections and infestations.
A method of treating a patient with a prescription drug using an exclusive computer database in a computer system for distribution.
A method to control abuse of a sensitive drug by controlling with a computer processor the distribution of the sensitive drug via an exclusivity central pharmacy that maintains a central database.
Method of treating a patient with a prescription drug using a computer database in a computer system for distribution.
Method of treating cataplexy in patients with narcolepsy.
Method of treating excessive daytime sleepiness and/or cataplexy in narcolepsy patients with sodium oxybate when divalproex sodium is concomitantly administered..
Method of treating excessive daytime sleepiness in patients with narcolepsy.
Zingo intradermal injection system is a drug delivery system that is capable of delivering fine dry powdered lidocaine hydrochloride monohydrate for local anesthetic action.
Zingo is a powder intradermal system that is capable of delivering fine dry powdered lidocaine hydrochloride monohydrate for local anesthetic action.
WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for reference only. Many of these treatments may be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field. The owner of this website will not be held liable for any injuries and deaths cause by following any home remedies. We have no control of what is posted.
Home Remedies for That
BAD BREATH Gargle with lemon juice. Eat plain unsweetened yogurt that contains Lactobacillus bacteria. Bad breath is neutralized for 12 to 24 hours.Sleslie | November 4th, 2017
PMS [Premenstrual Syndrome] Eat more nuts, such as almonds, as your period approaches. Mechanism - Riboflavins boosts neurotransmitters that reduce PMS symptomsFedup | November 5th, 2017
HEARTBURN [gastroesophageal reflux disease] Eat a high-fiber diet that include beans. Mechanism - Fiber helps move food out of the stomach faster reducing reflux.RudyardKipling | November 5th, 2017
IMPOTENCE [erectile dysfunction] Suffering from low testosterone impacts energy, strength and stamina, which is why Prime Test is a natural testosterone booster that revitalizes and restores your manhood.Jerry | November 29th, 2017
IMPOTENCE [erectile dysfunction] Don't lose your mojo in the bedroom. If you don't have a prescription to buy Viagra, there are more natural testosterone boosters on the market that can increase your libido and stamina. Mechanism - Horny Goat Weed, Tongkat Ali Extract, Saw Palmetto ExtractAntonchekov | July 15th, 2018
PREGNANCY [contraception] Emergency contraception is to only be used after unprotected sex, not for regular birth control. Emergency contraceptionthat contains the same hormone used in many birth control pills - just at a higher dose. Helps prevent pregnancy. It should not be used as regular birth control because it's not as effective. Mechanism - hormoneShizs | July 15th, 2018
STRESS [fatigue] Frankincense essential oil calms, fights fatigue, and increases circulation. Used with a carrier oil, it helps heal eczema, psoriasis and dandruff, all alongside that lovely scent.IvanTurgenev | July 15th, 2018
SORE THROAT [Pharyngitis] Licorice root has anti-inflammatory properties. Boil 1/2 ounce of licorice in 1 quart of water,... / ...can cause people to experience abnormal heart rhythms, high blood pressure, edema, lethargy, and/or congestive heart failure. The NIH has determined that there is insufficient data available to know if licorice is effective in treating any medical condition.
The FDA notes:
-Don’t eat large ... / ...if you have questions about possible interactions with a drug or supplement you take. Mechanism - glycyrrhizinJlaiii | August 11th, 2020
CHILD SKIN INFECTION [impetigo] Goldseal (Hydrastis canadensis), Oregon grape root (Mahonia aquifolium) and barberry (Berberis vulgaris) contain an antimicrobial that can impede the growth of Staphylococcus and Streptococcus. Create a tea using 1/2 ounce of root bark in 1 pint of water. Simmer for 20 minutes after initial boil. Let cool. Apply to infected area every 2 hours. Mechanism - berberineMaryFreeman | August 12th, 2020
URINARY TRACT INFECTION (UTI) [Cystitis] Cranberry juice is a well-know treatment for urinary tract infections. However, studies have shown that modern antibiotics are the only effective way to quickly eliminate a UTI. Cranberry juice has been shown to help prevent UTIs from occurring, though. It is believed cranberry juice disallows bacteria from adhering to the walls of the urinary tract. Mechanism - reduce bacteria adherenceJose3124 | September 20th, 2020
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.
Felter's Materia Medica on That
ABIES (Tsuga canadensis)TSCA ...tituents.The oleoresin Canada pitch, and a volatile oil known
as Oil of Hemlock or Oil of Spruce; that from the leaves is known as Pine-needle
Oil, and contains pinene, bornyl acetate, and cadinene;......th
pallid mucosa. In small doses, the specific medicine may be employed
n gastric irritation and in that of the urinary organs, in both of which
'there is an excess of mucous secretion. As a remedy fo...2
ABSINTHIUM (Artemisia absinthium)ARAB3 ...ed rest, with disagreeable
dreams, and morning sickness and vomiting. A chronic intoxication
ensues that is more fearful in its effects than that resulting from the
abuse of alcoholics. Epileptoid att......thus favoring digestion. For this
purpose it is sometimes useful in atonic dyspepsia; especially in that
form due to alcoholic excesses. Large doses irritate the stomach and
give rise to increased act...2
ACONITUM NEPALLUS ... to be but little, if at all, affected by aconite. The
kidney function is slightly increased, while that of the skin is
markedly influenced according to the quantity administered. The
motor nervous sy......ally at the periphery, are
notably impressed by even so-called therapeutic doses. It is quite clear
that aconite does not act strongly upon the cerebrum, except that
poisonous doses somewhat depress t......as an
anaesthetic. The mode of elimination of aconite is not yet well
determined, but it is thought that it is largely oxidized, thus
accounting for the short duration of its action. Indeed, the syste...2
ACTÆA ALBA. The rhizome and rootlets of Actaea alba, Bigelow (Nat. Ord. Ranunculaceae). A
perennial of the United States east of the Mississippi, abounding in... / ... White Baneberry, White Beads.
Principal Constituents.A non-acrid and non-bitter resin similar to that
obtained from black cohosh (cimicifuga). Albumen, starch, sugar, and gum are
present, but neith... / ...arising from derangement of the reproductive organs. Like
cimicifuga it is useful in atonic indigestion of the nervous dyspepsia
type.
2
ÆSCULUS GLABRA ...tory
systems. Its action is probably strongest on the spinal nerves, and in
some respects resembles that of strychnine. The cerebrum is also
impressed by it. Toxic symptoms include dizziness, fixation......a sense of constriction back of the upper
portion of the sternum, with or without irritative cough, that is relieved
by it. It is useful in intestinal irritability with the contractive colic-like
pain......as often completely fails to relieve. Its
action upon visceral disorders is practically the same as that
mentioned under Hippocastanum (which see).
Aesculus sometimes relieves uterine congestion with ...2
AGARICUS (Amanita muscaria) ...ldom used, but possesses undoubted power
over the secretions and the nervous system. The chief uses that have
been made of it, and for these even the muscarine sulphate or nitrate
have been mostly emp......h fungus for involuntary
twitching of the muscles of the face, forehead, and even of the eyes, so
that objects are not well seen because they seem to move; drawing of
the tissues of the forehead and...2
ALETRIS FARINOSA The rhizome of Aletris farinosa, Linné, gathered after the plant has flowered (Nat.
Ord. Haemodoraceae). United States. Dose, 5 to 60... / ...ation.Specific Medicine Aletris. Dose, 5 to 60 drops.
Action and Therapy.Owing to the confusion that has long existed
resulting from the unwitting substitution of aletris, for Helonias
(Chamaeliri... / ...carminative effects thus
ascribed would seem to belong to helonias rather than to aletris, which
is neither bitter nor aromatic like the former.
2
ALLIUM SATIVUM The bulb of Allium sativum, Linné (Nat. Ord. Liliaceae). Sicily, Asia Minor, and
Central Asia; cultivated also in the United States and Europe.... / ...Dose, 1 fluidrachm.
Action and Therapy.External. Stimulant and rubefacient. Garlic
poultice, like that of the onion, may be applied with benefit in acute
respiratory and abdominal inflammations. It ...2
ALOEALOE ...arge. As it
takes from 10 to 15 hours to operate, it should be administered in the
early evening so that evacuation may occur in the morning. When
given alone it causes considerable griping and often ......bstinate constipation. It has had a large
vogue as an after-dinner pill, but is now little used for that purpose. As
a rule it is a good agent for use in atonic chronic constipation, but
should never ......mpaction in the insaneparticularly in hypochondriasis
and melancholiaaloes is probably the best that can be given. The
improvement in the mental state often will be commensurate with the
bettermen...2
APOCYNUM CANNABINUM ...ed by it as are probably the arterial coats. Contraction of the
renal arteries also takes place, so that while less blood passes at a time
through the kidneys, the act of filtration is more perfect an......h the kidneys, the act of filtration is more perfect and marked
diuresis results. Though long known that diuresis was one of its most
prominent results, the knowledge that this is due to the better ca...... small doses employed in Eclectic therapeutics seldom
occasion any of the above-named symptoms save that of severe watery
purging, which may occur suddenly, when the drug has been
administered persist...2
ARISÆMA TRIPHYLLUM ...causing a persistent and
intensely acrid impression on the tongue, lips, and fauces, something
like that of a severe scald, with considerable pricking. Slight
inflammation and tenderness may follow. T......f sore throat, intensely
painful, swollen and fetid, with deep or purplish-red membranes
similar to that of the angina of scarlet fever. It is also useful in chronic
laryngitis aggravated by singing o...2
ARNICA MONTANA ...tusions. It is often serviceable to
remove ecchymoses, and it gives grateful relief to sore muscles that
have undergone much strain and exertion. A glycerite has been
effectually used upon bites of mo......
the latter, which should always be well diluted, the surface should not
be covered or bandaged, so that evaporation may take place freely.
Internal. Arnica is a greatly unappreciated medicine. It has......t-strain due to exertion, overwork, or
from long marching. It also benefits in the heart debility that follows
severe strain, worry, or excitement. Dull aching pain in the praecordia,
due to lifting...2
ASCLEPIAS INCARNATA The root of Asclepias incarnata, Linné (Nat. Ord. Asclepiadaceae). Common in damp
and wet grounds throughout the United States. Dose, 1 to 60... / ...uted for digitalis in cases
of edema dependent upon cardiac insufficiency. Its action is similar to
that of foxglove, without the irritating effects upon the gastric
membranes. In fact, in small doses...2
ASCLEPIAS TUBEROSA ...ingly and
almost insensibly. Its regulation of the true secretion of the skin more
nearly resembles that of normal or insensible perspiration than that
caused by any other diaphoretic, corallorhiza po...... possible on account of the pain
and soreness it occasions. Bronchial secretion is arrested, though that
of the skin may be in evidence. The early Eclectics were neither
dreaming nor romancing when th......apted to control vascular
disturbances in the area supplied by the bronchial arteries, and
suggests that by reserving it for this use we shall lessen its liability to
confusion with other appropriate ...2
AVENA SATIVA ... it is useful, not as
an antirheumatic, but for the debility underlying the rheumatic
diathesis, so that the patient is less affected by meteorologic
influences. Probably its chief value as a medicine......conditions mentioned. However, many agents of this
type sometimes, in exceptional cases, accomplish that which no other
remedy seems to do. To fortify some of the claims made for this remedy
is to unw...2
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.
Physician's Materia Medica on That
ACID VALERIANIC AND VALERIANATES Compounds of Valerianic Acid produce a quieting effect in
hysterical conditions and are prescribed usually with reference to
that effect. The uncombined acid is never used.
a. Ammonium Valerianate. This is the salt of Valerianic
Acid most frequently prescribed. It is useful innervous headaches,
hysteria and the nervousness connected with pregnancy or the meno
pause. Very commonly combined with bromides. Dose, 0.12 to 0.6
(2 to 10 grs.).
b. Ferric Valerianate. Prescribed commonly in combination
w3
ALKAL-ANTISEPTINE A pleasantly aromatic liquid having an alkaline reaction and
serving as an efficient antiseptic and germicide although not pois
onous to the human subject. It differs from Antiseptine, q. v. in
that it contains glycerin and is distinctly alkaline. Its chief active
constituents are Thymol, Eucalyptol, Menthol, Sodium Borate and
Sodium Benzoate. Internally it may be given in teaspoonful doses
as a gastric and intestinal antiseptic with antacid properties, but it
is much more commonly used locally 3
AMYL NITRITE Antispasmodic, reducing arterial tension and so causing momen
tary acceleration of the heart beat. Used chiefly by inhalation to
relax spasm, notably in asthma, in whooping cough. in spasmodic
croup, in epileptic seizures, in tetanus and strychnine poisoning and in
spasmodic dysmenorrhea. It is a valuable agent also in angina pec
toris and in sudden heart failure, but must be used always intelli
gently and with due caution remembering that it is a depressant,
not a stimulant. Dose. usually 0.13 3
BONESET (Eupatorium)TAMAU2 The leaves and flowering tops of EUPATORIU M PERFOLIATUM,
Lin. Tonic, diaphoretic, febrifuge. in large doses laxative and
nauseant or emetic. The remedy deserves more attention than it
has received, its range of use being essentially the same as that of
Matricaria.3
CINCHONIDINE Alkaloid from CINCHONA BARK, having the general properties of
Quinine (q. v.) but not so liable to produce ringing in the ears and
vertigo as that alkaloid. Dose of the sulphate as tonic, 0.015 to 0.13
Grm. (1/2 to 2 grs.) three times a day; as antiperiodic, 0.6 to 1.3 Grm.
(10 to 20 grs.) during the six hours preceding the expected paroxysm.3
COD LIVER OIL The oil obtained from the fresh livers of GADU8 MoRRHUA, Lin.
Readily digested and having a peculiar power of improving nutrition.
It is believed that this property resides in certain constituents of
the oil not of a fatty nature and accordingly some of the preparations
contain the non-fatty portions only of the oil. Ordinary dose for an
adult, 15 c. c. (half a fluidounce), three times a day.3
COPPER ARSENITE Intestinal antiseptic; prescribed in diarrhea either iodiop athic or
that attending typhoid fever. Dose, 0.00006 to 0.0025 Grm. (1-1000 to
1-25 gr.).3
COTTON-ROOT The bark of the root of GOSSYPIUM HERBACEUM, Lin. Emmena
gogue, oxytocic, abortifacient. Its action resembles that of ergot.3
DUBOISIADUBOI The leaves of DUBOISIA MYOPOROIDES, R. Br. Resembles Bella
donna in its medicinal properties, but more distinctly hypnotic and
calmative. The extract, also the alkaloid derived from the leaves, is
used to produce mydriasis, its action being more prompt than that
of atropine, and the effect passing off more quickly.3
ECHINACEA The root of BRAUNERIA PALLIDA, (Nutt.) Brit. [Echinacea angustifolia, DC.].
Antiseptic, vulnerary, alterative; has a pungency
like that of pellitory. Locally applied has a powerful aphrodisiac
action.3
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.
Physician's Therapeutics Memoranda on That
ASTHMA For immediate relief, the smoke from mixtures of stramonium
or henbane leaves with nitre and a... / ...e relief
or inhalations of oxygen; if of nasal origin application to nasal mu
cous membrane of a six per cent. solution of cocaine hydrochloride,
See that all hygienic conditions are favorable.
For general treatment, tonics, especially strychnine; grindelia,
euphorbia pilulifera; iodides, arsenic; i...3
CATARRH, NASAL (See also Coryza) Chronic Nasal Catarrh in our climate is an intractable affection.
In mild cases Alkal-Antiseptine, well diluted with water and ap
plied twice daily by aid of the little douche that accompanies it, is all
the treatment needed. Application of Iodosyl once daily has a most
happy effect. Tonics are often indicated.
Atrophic Nasal Catarrh calls for use of more active antiseptics
and a stimulating treatment, silver nitrate, iodine and hydrogen
peroxide being the most useful remediés.3
CHOLERA, ASIATIC As prophylactic measures, avoid all uncooked foods, especiaHy
water that has not been boiled; sulphuric acid lemonade. In early
stage,... / As prophylactic measures, avoid all uncooked foods, especiaHy
water that has not been boiled; sulphuric acid lemonade. In early
stage, camphor, salol and salophen; diluted sulphuric acid, which de
stroys the cholera ba... / ...and hot baths or hot water bed; strychnine and atropine
hypodermatically; subcutaneous injection of normal salt solution.3
DEBILITY Treatment varies with cause. Hematinic tonics are generally
indicated. Eupeptic H ypop hosphites, Haemo-mangan with Arsenic,
Elixir Iron, Quinine and Strychnine, Vitalic Hypophosphites, may be
particularized.
For remedies in sexual debility see Aphrodisiacs, but in most
cases general roborant measures with moderation in sexual indul
gence are all that is required.3
ECZEMA Improve general health of patient by hygienic measures. See
that the diet is simple and substantial. Fats, salted meats, pastry
and all... / Improve general health of patient by hygienic measures. See
that the diet is simple and substantial. Fats, salted meats, pastry
and all indigestible articles of food must be interdicted. See that
the excretory ... / ...use more stimulating remedies—ointments
of tar, resorcin, green soap, ichthyol, salicylic acid or oil of cade.3
EPISTAXIS In severe cases, surgical measures must be resorted to... / ...ng
anterior and posterior nares). Styptic solutions (alum, tannin,
vegetable astringents, Monsel’s solution, vinegar) may be used, or
else remedies that contract the capillaries (fluid extract ergot, anti
pyrin, extract suprarenal capsule or internally fluid extract ergot).
The hot foot bath to dr...3
FEVER The remedies commonly resorted to include; 1st cardiac or ar
terial sedatives, particularly aconite, 2d antipyretics causing reduc
tion of... / ...ynes, which may well be combined with diaphoretics. These
several classes of remedies must be suited to the individual case,
bearing in mind the fact that fever is not in and of itself necessarily
an evil thing.3
GASTRIC CATARRH At first withhold all food, later give milk and lime water. Cleanse
stomach of irritating... / ...itrate and cerium oxalate are useful. Later regulate
diet carefully and prescribe as tonic a mixture containing columbo
and sodium phosphate. Be sure that medicines do not irritate the
stomach. For pain apply spice poultice or hot water bag.
In Chronic Gastric Catarrh, lavage is the most important r...3
GASTRIC ULCER Nourish patient by enemas so that stomach may have complete
rest. Internally, silver nitrate and resorcin with codeine or morph
ine, antacids, especially sodium bicarbonate with bismuth subcar
bonate; counter-irritation by tincture iodine or mustard leaves;
antiemetics as needed; for hematemesis, emulsion of oil turpentine,
antipyrin, alum or other styptic; suprarenal extract. Bowels must
be regulated by enemata.3
GOITRE In simple Goitre (Bronchocele), ointment of mercuric iodide or
tincture iodine externally; creosotide or potassium iodide and extract
of thymus gland internally. In Exophthalmic Goitre, belladonna,
strophanthus. ergot and sparteine are among the remedies that
have been found serviceable. Extract of suprarenal capsules
promises good results.3
HEADACHE Seek the cause and govern treatment accordingly. Distinguish
articularly congestive from anemic headaches. In the former ergot
and vascular sedatives are useful, in the latter stimulating remedies
are indicated. See that excretions are normal, that the eyes are not
under strain from errors of refraction. that hygenic conditions are
good and that the patient takes suflicient exercise and recreation.3
HEART DISEASE In organic diseases of the heart. remedies must be adapted to
symptoms presented. Digitalis and... / ...he heart calls for cardiac tonics
when it arises from weakness, aconite in the rarer cases where the
heart has been over developed by severe exercise that has been dis
continued. Where palpitation arises from debility, general tonics
are indicated, particularly nux vomica and iron.
In cardiac failur...3
MYALGIA The treatment is that given for Lumbago, q. v.3
PRURITUS In absence of local cause, general Pruritus calls for tonic treat
ment, particularly for use of arsenic. Give attention to stomach,
bowels and kidneys.'
The local remedies that give most relief are lotions of borax or of
sodium bicarbonate or hyposulphite to which carbolic acid may be
advantageously added (one or two drachms to the pint). Menthol.
resorcin, thymol. boric acid and ichthyol are also useful. Alkal
Antiseptine, diluted with from four to eight parts of water is an
excellent remedy.3
SCABIES Apply parasiticideointments; sulphur, naphthol, mercuric chlo
ridaammoniated mercury, potassium a1senite (Fowler's solution) are
among the most eflicient, and sulphur in some form is that commonly
selected.3
