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What are migraines?
Migraines are a recurring type of headache. They cause moderate to severe pain that is throbbing or pulsing. The pain is often on one side of your head. You may also have other symptoms, such as nausea and weakness. You may be sensitive to light and sound.
What causes migraines?Researchers believe that migraine has a genetic cause. There are also a number of factors that can trigger a migraine. These factors vary from person to person, and they include:
- Stress
- Anxiety
- Hormonal changes in women
- Bright or flashing lights
- Loud noises
- Strong smells
- Medicines
- Too much or not enough sleep
- Sudden changes in weather or environment
- Overexertion (too much physical activity)
- Tobacco
- Caffeine or caffeine withdrawal
- Skipped meals
- Medication overuse (taking medicine for migraines too often)
Some people have found that certain foods or ingredients can trigger headaches, especially when they are combined with other triggers. These foods and ingredients include:
- Alcohol
- Chocolate
- Aged cheeses
- Monosodium glutamate (MSG)
- Some fruits and nuts
- Fermented or pickled goods
- Yeast
- Cured or processed meats
About 12% of Americans get migraines. They can affect anyone, but you are more likely to have them if you:
- Are a woman. Women are three times more likely than men to get migraines.
- Have a family history of migraines. Most people with migraines have family members who have migraines.
- Have other medical conditions, such as depression, anxiety, bipolar disorder, sleep disorders, and epilepsy.
There are four different phases of migraines. You may not always go through every phase each time you have a migraine.:
- Prodome. This phase starts up to 24 hours before you get the migraine. You have early signs and symptoms, such as food cravings, unexplained mood changes, uncontrollable yawning, fluid retention, and increased urination.
- Aura. If you have this phase, you might see flashing or bright lights or zig-zag lines. You may have muscle weakness or feel like you are being touched or grabbed. An aura can happen just before or during a migraine.
- Headache. A migraine usually starts gradually and then becomes more severe. It typically causes throbbing or pulsing pain, which is often on one side of your head. But sometimes you can have a migraine without a headache. Other migraine symptoms may include
- Increased sensitivity to light, noise, and odors
- Nausea and vomiting
- Worsened pain when you move, cough, or sneeze
- Postdrome (following the headache). You may feel exhausted, weak, and confused after a migraine. This can last up to a day.
Migraines are more common in the morning; people often wake up with them. Some people have migraines at predictable times, such as before menstruation or on weekends following a stressful week of work.
How are migraines diagnosed?To make a diagnosis, your health care provider will:
- Take your medical history
- Ask about your symptoms
- Do a physical and neurological exam
An important part of diagnosing migraines is to rule out other medical conditions which could be causing the symptoms. So you may also have blood tests, an MRI or CT scan, or other tests.
How are migraines treated?There is no cure for migraines. Treatment focuses on relieving symptoms and preventing additional attacks.
There are different types of medicines to relieve symptoms. They include triptan drugs, ergotamine drugs, and pain relievers. The sooner you take the medicine, the more effective it is.
There are also other things you can do to feel better:
- Resting with your eyes closed in a quiet, darkened room
- Placing a cool cloth or ice pack on your forehead
- Drinking fluids
There are some lifestyle changes you can make to prevent migraines:
- Stress management strategies, such as exercise, relaxation techniques, and biofeedback, may reduce the number and severity of migraines. Biofeedback uses electronic devices to teach you to control certain body functions, such as your heartbeat, blood pressure, and muscle tension.
- Make a log of what seems to trigger your migraines. You can learn what you need to avoid, such as certain foods and medicines. It also help you figure out what you should do, such as establishing a consistent sleep schedule and eating regular meals.
- Hormone therapy may help some women whose migraines seem to be linked to their menstrual cycle
- If you have obesity, losing weight may also be helpful
If you have frequent or severe migraines, you may need to take medicines to prevent further attacks. Talk with your health care provider about which drug would be right for you.
Certain natural treatments, such as riboflavin (vitamin B2) and coenzyme Q10, may help prevent migraines. If your magnesium level is low, you can try taking magnesium. There is also an herb, butterbur, which some people take to prevent migraines. But butterbur may not be safe for long-term use. Always check with your health care provider before taking any supplements.
NIH: National Institute of Neurological Disorders and Stroke
There FDA Approved Drugs
- Use of flibanserin or a pharmaceutically acceptable acid addition salt thereof to treat hypoactive sexual desire disorder (hsdd).
- Treatment of a neurodegenerative disease or a symptom thereof.
- A method of increasing the testosterone blood level of a person in need thereof.
- A method of increasing the testosterone blood level of an adult male subject in need thereof.
- A method of transdermal administration of a physiologically active agent to a subject..
- A method of transdermally delivering testosterone.
- Testosterone replacement therapy in males for conditions associated with a deficiency or absence of endogenous testosterone.
- As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
- Lowering plasma glucagon in a subject in need thereof, including one with type 2 diabetes, by administering an exendin or analog, such as exendin-4.
- Method for treating type 2 diabetes using a sustained-release composition containing exenatide.
- Reducing food intake in a subject with type 2 diabetes by administering an exendin, such as exendin-4.
- Reducing gastric motility or delaying gastric emptying by administering an exendin, such as exendin-4.
- Reductions in body weight are observed with exenatide.
- Treating type 2 diabetes mellitus with exenatide by stimulating insulin release.
- Treatment of type 2 diabetes.
- As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
- Lowering plasma glucagon in a subject in need thereof, including one with type 2 diabetes, by administering an exendin or analog, such as exendin-4.
- Method for treating type 2 diabetes using a sustained-release composition containing exenatide.
- Reducing food intake in a subject with type 2 diabetes by administering an exendin, such as exendin-4.
- Reducing gastric motility or delaying gastric emptying by administering an exendin, such as exendin-4.
- Reductions in body weight are observed with exenatide.
- Treating type 2 diabetes mellitus with exenatide by stimulating insulin release.
- Treatment of type 2 diabetes.
- Lowering plasma glucagon in a subject in need thereof, including one with type 2 diabetes, by administering an exendin or analog, such as exendin-4.
- Reducing food intake in a subject with type 2 diabetes by administering an exendin, such as exendin-4.
- Reducing gastric motility or delaying gastric emptying by administering an exendin, such as exendin-4.
- Stimulating insulin release by administering exenatide.
- Treating type 2 diabetes mellitus with exenatide by stimulating insulin release.
- Use of exenatide may result in reduction in appetite..
- Use of exenatide may result in reduction in body weight.
- Management of mild to moderate pain, management of moderate to severe pain as an adjunct to opioid analgesics in a critically ill patient with intravenous ibuprofen in need thereof.
- Management of mild to moderate pain, management of moderate to severe pain as an adjunct to opioid analgesics, reduction in fever through anti-inflammatory, analgesic, and antipyretic activity.
- Management of mild to moderate pain, management of moderate to severe pain as an adnunct to opioid analgesics, reduction in fever through anti inflammatory, analgesic, and antipyretic activity.
- Methods of treating pain, inflammation and/or fever in a critically ill patient with intravenous ibuprofen in need thereof.
- Methods of treating pain, inflammation and/or fever with intravenous ibuprofen such that mean arterial blood pressure does not increase the dosage interval.
- Method for treating acute elevations of blood pressure in human subject in need thereof.
- Method for treating acute elevations of blood pressure in human subject in need thereof.
- Method for treating acute elevations of blood pressure in human subject in need thereof.
- Method for treating acute elevations of blood pressure in human subject in need thereof.
- Method for treating acute elevations of blood pressure in human subject in need thereof.
- For the treatment of attention deficit hyperactivity disorder (adhd).
- Method for transdermally delivering a drug to a user in need thereof.
Eli Lilly And CoMay 26, 2015
- Treatment of a neurodegenerative disease or a symptom thereof.
- Treatment of hallucinations and delusions associated with parkinson's disease psychosis.
- Treatment of parkinson's disease psychosis.
- Treatment of psychosis or a symptom thereof.
- Treatment of psychosis.
- Method of treating pulmonary hypertension by administering treprostinil or a salt thereof by inhalation using a device.
- Treatment of pulmonary hypertension by inhalation.
- Method of treating travelers' diarrhea.
- The treatment of patients with travelers' diarrhea (td) or the reduction in risk of overt hepatic encephalopathy (he) recurrence.
Home Remedies for There
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Mechanism - Horny Goat Weed, Tongkat Ali Extract, Saw Palmetto ExtractAntonchekov | July 15th, 2018
   Licorice root has anti-inflammatory properties. Boil 1/2 ounce of licorice in 1 quart of water,... / ...ause people to experience abnormal heart rhythms, high blood pressure, edema, lethargy, and/or congestive heart failure. The NIH has determined that there is insufficient data available to know if licorice is effective in treating any medical condition.
The FDA notes:
-Don’t eat large amoun... / ...if you have questions about possible interactions with a drug or supplement you take.
Mechanism - glycyrrhizinJlaiii | August 11th, 2020
Felter's Materia Medica on There
   ... medicine may be employed n gastric irritation and in that of the urinary organs, in both of which 'there is an excess of mucous secretion. As a remedy for passive hemorrhages it has little to commend....... Both the specific medicine and the oil may be incorporated into cough medicines, to be used where there is excessive secretion of mucus and the cough is largely precipitated by a feeble and relaxed ...2
   The dried tuberous root of Aconitum Napellus, Linné (Nat. Ord. Ranunculaceae). Mountains of Europe and Asia, and northwestern North America.... / ...the thrilling or tingling sensation will be more generally experienced, with perhaps some numbness. There may be dizziness most marked upon assuming the upright posture, pain in the head, acute body p... / ...approaching from the extremities to the body. Excessive sweating comes on, rapidly lowering the body temperature, dimness of vision, 2
   The rhizome and rootlets of Actaea alba, Bigelow (Nat. Ord. Ranunculaceae). A perennial of the United States east of the Mississippi, abounding in... / ... a well-sustained reputation as a remedy for after-pains; and may be used in ovarian disorders when there is pain or uneasy sensations in or around the ovaries, with extreme sensitiveness to touch or ...2
   The whole plant of Adonis vernalis, Linné. (Nat. Ord.... / ...ning. Adonis slows, regulates, and strengthens the heart's contractions, raises blood pressure, and thereby acts as a diuretic. It also causes deeper and slower breathing, and in proper cases overcome......s been advised in epilepsy, administering it with bromide of potassium. It should not be given when there is gastro-intestinal irritation or inflammation. 2
   The bark and fruit of Aesculus glabra, Willdenow (Nat. Ord. Sapindaceae). A small fetid tree common to the central portion of the United... / ...ion prominent and dyspnea prolonged, it relieves such conditions as continuous asthmatic breathing. There is a sense of constriction back of the upper portion of the sternum, with or without irritativ... / ...Aesculus deserves further study to determine its status as a remedy for nervous disorders, and especially its control over visceral neuralgias. 2
   ...scarine and a toxalbumen phallin, both of which are deadly agents. While salt abstracts the latter, there is no known antidote after it has been absorbed. Therapy.Agaricus is seldom used, but posses......tion to fall backward. Webster thought it useful in typhoid conditions and spinal irritation when there is tremor, restlessness, and desire to get out of bed. These indications are of homeopathi...2
   The rhizome of Aletris farinosa, Linné, gathered after the plant has flowered (Nat. Ord. Haemodoraceae). United States. Dose, 5 to 60 grains. Common Names: Blazing Star, Star... / The rhizome of Aletris farinosa, Linné, gathered after the plant has flowered (Nat. Ord. Haemodoraceae). United States. Dose, 5 to 60 grains. ... / ...and borborygmus. Even the carminative effects thus ascribed would seem to belong to helonias rather than to aletris, which is neither bitter nor aromatic like the former. 2
   The bulb of Allium sativum, Linné (Nat. Ord. Liliaceae). Sicily, Asia Minor, and Central Asia; cultivated also in the United States and Europe.... / ...colds, especially when tending to become chronic or frequently repeated. It should not be used when there is marked irritation or inflammation. As a food, garlic is a stimulant to digestion if not use...2
   The dried juice of the leaves of several species of Aloe: (1) Aloe Perryi, Baker; (2) Aloe vera, Linné; (3) Aloe ferox, Miller. (Nat. Ord.... / ...ous return, small doses of aloes or aloin may improve conditions, but it should never be given when there is active hemorrhoidal inflammation. In very small doses aloin is useful in rectal prolapsus, ...2
   The root of Apocynum cannabinum, Linné (Nat. Ord. Apocynaceae) gathered in autumn after the leaves and fruit have matured. Grows throughout the United States. Dose, ......to remedy with apocynum. It is a vascular stimulant. Such results one would not expect to obtain if there were circulatory obstruction or active fever. The only apparent exception, in which it is adap......nout tissues or to restore damaged vascular valves. We must not hope to work miracles with it where there are such structural lesions as incurable or malignant organic diseases of the heart, liver, or...2
   ...sion. The keynote for arnica is spinal and vagal enervation. It should be brought into service when there is deficient nervous response, sluggish vascular power, and in almost all conditions in which ......ges of exhausting diseases, where spinal innervation is poor, control over the sphincters lost, and there is feeble respiration due to central vagal impairment, it is a most important stimulant. It sh...2
   The root of Asclepias incarnata, Linné (Nat. Ord. Asclepiadaceae). Common in damp and wet grounds throughout the United States. Dose, 1 to 60... / ...Specific Medicine Swamp Milkweed. Dose, 1 to 60 drops. Action and Therapy.Diuretic and vermifuge. There is good reason to believe this agent a good diuretic to be substituted for digitalis in cases ... / ...value in chronic catarrh of the stomach. In powder, 10 to 20 grains, 3 times a day, it is said to expel lumbricoids. 2
   ...d even though the patient be freely perspiring, for sometimes when the liquid excretion is abundant there is a retention of the solid detritus, the removal of which is one of the effects of asclepias....... pain, temperature, to favor expectoration, and restore checked perspiration. When cough is dry and there is scant bronchial secretion, asclepias stimulates the latter and thus relieves the irritation......s for it. The asclepias condition in broncho-pulmonic disorders shows either a hot and dry skin, or there is pungent heat of the skin with inclination to moisture, the pulse is usually full and active...2
   The unripe seed of the Avena sativa, Linné, and the farina derived from the ripened seed (Nat. Ord. Graminaceae). Probably indigenous to Sicily... / ...n following typhoid and other low fevers and is thought to hasten convalescence, particularly where there is much nervous involvement and enfeebled action of the heart. In the nervous erethism or the ... / ...off the habit has not been sustained. In our own experience we have utterly failed to accomplish any good with it in any form of drug habit. 2
   ... in the peculiar appearance of the parts affected, of the membranes, and of the patient as a whole. There is a peculiar duskiness of a bluish or purplish hue of the skin and mucous structures, and usu...... is a peculiar duskiness of a bluish or purplish hue of the skin and mucous structures, and usually there is fetor. The face has a bluish, swollen appearance, with expressionless countenance, like one......h, swollen appearance, with expressionless countenance, like one who has been long exposed to cold. There may be ulcers of an indolent character, with bluish or purplish edges. The excretions are feti...2
Physician's Materia Medica on There
   Glucoside obtained from Foxerglove, q. v. Readily soluble in water and therefore well suited for hypodermatic use. [The French Digitalin is considerably stronger, but is less soluble and is not so uniform a product]. Dose, 0.0006 to 0.03 Grm. (1-100 to 1/2 gr.).3
   An admirable general tonic having a wide range of usefulness in de bilitated conditions. Its active constituents are in each fluidrachm; Calcium Hypophosphite,1/2 gr.; Potassium Hypophosphite, 1 gr.; Manganese Hypophosphite, 1/4 gr.; Ferric Hypophosphite, 1/4 gr.; Quinine Hypophosphite, 1-16 gr.; Strychnine Hypophospbite, 1-80 gr.; Pancreatin Saccharated, 1 gr.; Pepsin Saccharated, 1 1/2 grs. The combination has therefore, 1st the specific action bf the hypo phosphites as restoratives, supplying3
   Synthetic alkaloid, a derivative of MORPHINE. A sedative resembling codeine rathor than morphine, but more active than the former. Unlike morphine it stimulates rather than depresses the respiratory center, hence is particularly valuable as a remedy for cough. Does not stupify or constipate like morphine, but must be used with caution where there is a weak heart. Dose, 1-20 to 1-16 gr. three times a day.3
   Phosphorus enters into the composition of all nerve structures as well as of the bones. It constitutes therefore an essential element of the food. It is generally believed by physicians that the hypophosphites produce their beneficial effects by supplying phosphorus in a readily assimilable form. They are therefore largely prescribed in many conditions of depressed vitality, especially in nervous prostation and in tubercular diseases. a. Calcium Hypophosphite. A food for bone as well as nerve. 3
   The fruit of JUNIPERUs COMMUNIS, Lin. Stimulant diuretic. Much used in chronic affections of the genito-urinary tract; must be avoided while there is active inflammation. Active constituent the volatile oil, which is oflicial.3
   A preparation representing the nitrogenous elements of beef, milk and cereal grains in a vinous vehicle. The nutrient value of such a preparation is far higher than that of a wine or elixir of beef prepared from the extract of beef. Taken in connection with meals, the preparation serves to assist digestion by a direct stimulant action on the glands of the stom ach. It is of use, therefore, not only in convalescence from acute illness, but in enfeebled conditions of the system generally where the3
   An extract from the PANCREATIC gland of an animal, generally the hog. It has... / ...e power of peptonizing albuminoids, of converting starch into sugar and of emulsifying fats. 1t has therefore a far wider range of usefulness than pepsin. It is prescribed as an aid to intestinal dige... / ...(5 grains) “pure” p3
   A distinctly poisonous salt to be used therefore with caution. Its most important use is as a gargle in acute pharyngitis; applied locally and taken internally in stomatitis and in mercurial sore mouth; much used in tablets and lozenges for ulcerated mouth and throat. Dose 0.3 to 1.0 Grm. (5 to 15 grs.).3
   A compound of PHENOL with SALICYLIC ACID, having the proper ties of both of its constituents. Used as an intestinal ant iseptic; in rheumatism and neuralgia; in intestinal indigestion, fermentative diarrhea, cholera morbus, and asiatic cholera; in duodenal catarrhand catarrhal jaundice, and in gonorrhea. Contra-indicated where there is congestion or inflammation of the kidneys. Ordinary adult dose, 0.2 to 0.3 Grm. (3 to 5 grs.) three or four times a day. [Since Saloi is insoluble in water and a3
   Alkaloid obtained from CYTISUS SCOPARIUS, (L.) Link., (Broom. u. v.). Diuretic and cardiac stimulant. Used in the same way as Digitalis, or combined therewith; locally applied in erysipelas. Dose of the sulphate, 0.015 to 0.06 Grm. (1/4 to 1 gr.).3
Physician's Therapeutics Memoranda on There
   Keep parts clean by frequent bathing in pure water; to disinfect use solution boric acid, 1%; silver nitrate, 2 gr. to fl. o2.; Iodosyl oint ment, 6% ; carbolic acid, 1.5%; potassium permanganate, 1 gr. to fl, oz. If there is active inflammation apply lotion of lead water. For dust ing powder zinc oleate, Iodosyl or zinc oxide.3
   In the incipient stage, quinine with a little Dover powder and a laxative may ward off the attack. If inflammatory action... / ...ses, use terpin hydrate or terebene, oil oi sandalwood, eucalyptol and similar remedies. Eucalyptol in spray or by inhalation is very eflicient. When there is hypersecretion, avoid ammonium chloride and use belladonna, strychnine and counter-irritation.3
   Medicate no more than is necessary. Prescribe regular open air exercise, regularity in going to... / ... Apolinaris before breakfast; if necessary prescribe general tonics. The laxatives best suited for habitual use are; 1, glycerin sup positories, when there is simply inertia of the rectum; 2, senna (particularly a cold infusion, or the oflicial compound liquorice pow der) or cascara sagrada (fluid e...3
   For local application Iodosyl surpasses all other remedies; atro pine if there is a tendency to iritis. Tonic and roborant treatment is generally indicated.3
   During the seizure, amyl nitrite is the remedy most likely to be of service; chloroform must be... / ...ust be given well diluted, after meals. beginning with 10 grain doses and increasing to 25 or 30 grs., provided it does not disturb the digestion. If there is anemia, Combine with ferrous bromide or with Solution Gold and Arsenic Bmmides, N., B. & Co. Bromides of sodium and ammonium may be often adv... / ...hydrate. In children, ascertain whether the irritation is due to worms and treat accordingly.3
   Theremedies of real value are general tonics, particularly nux vomica, phosphorus and iron. Mere sexual stimulants do harm rather than good.3
   Prolonged application of hot water is the most important item in the treatment. If there is persistent swelling, apply Glycemplasma. or cover with bandage saturated with distilled extract witch hazel or tincture arnica. Later apply supporting bandage and use stimulat ing liniments.3
References
2) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
3) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.
