Gastric Ulcer
A peptic ulcer is a sore in the lining of your stomach or your duodenum, the first part of your small intestine. A burning stomach pain is the most common symptom. The pain:
- Starts between meals or during the night
- Briefly stops if you eat or take antacids
- Lasts for minutes to hours
- Comes and goes for several days or weeks
Peptic ulcers happen when the acids that help you digest food damage the walls of the stomach or duodenum. The most common cause is infection with a bacterium called Helicobacter pylori. Another cause is the long-term use of nonsteroidal anti-inflammatory medicines (NSAIDs) such as aspirin and ibuprofen. Stress and spicy foods do not cause ulcers, but can make them worse.
To see if you have an H. pylori infection, your doctor will test your blood, breath, or stool. Your doctor also may look inside your stomach and duodenum by doing an endoscopy or x-ray.
Peptic ulcers will get worse if not treated. Treatment may include medicines to reduce stomach acids or antibiotics to kill H. pylori. Antacids and milk can't heal peptic ulcers. Not smoking and avoiding alcohol can help. You may need surgery if your ulcers don't heal.
NIH: National Institute of Diabetes and Digestive and Kidney Diseases
Gastric Ulcer FDA Approved Drugs
NEXIUM [Esomeprazole Magnesium2C17H18N3O3SMg3H2O]
RX
- eq 10mg base/packet (oral for suspension, delayed release)
eq 2.5mg base/packet (oral for suspension, delayed release)
eq 20mg base (oral capsule, delayed rel pellets)
eq 20mg base/packet (oral for suspension, delayed release)
eq 40mg base (oral capsule, delayed rel pellets)
eq 40mg base/packet (oral for suspension, delayed release)
eq 5mg base/packet (oral for suspension, delayed release)
Astrazeneca PharmsFeb 27, 2008
- Pediatric use aged 1-11 years, gerd and erosive esophagitis.
VIMOVO [Esomeprazole Magnesium2C17H18N3O3SMg3H2O : NaproxenC14H14O3]
RX
- eq 20mg base : 375mg (oral tablet, delayed release)
eq 20mg base : 500mg (oral tablet, delayed release)
Horizon Pharma UsaApr 30, 2010
- Relief of signs and symptoms of arthritis and risk-reduction of nsaid-associated gastric ulcer.
- Risk-reduction of nsaid gastric ulcer in patients requiring chronic nsaid treatment.
- Risk-reduction of nsaid-associated gastric ulcer in patients requiring nsaid treatment.
- Risk-reduction of nsaid-associated gastric ulcer.
- Risk-reduction of nsaid-associated gastric ulcers in patients also taking low dose aspirin.
YOSPRALA [AspirinC9H8O4 : OmeprazoleC17H19N3O3S]
RX
- 325mg : 40mg (oral tablet, delayed release)
81mg : 40mg (oral tablet, delayed release)
Aralez PharmsSep 14, 2016
- Treatment or secondary prevention of cardiovascular disease, cardiovascular events, or cerebrovascular events and risk-reduction of aspirin-associated gastric ulcers.
ZEGERID [OmeprazoleC17H19N3O3S : Sodium BicarbonateCHO3Na]
RX
- 20mg/packet : 1.68gm/packet (oral for suspension)
20mg : 1.1gm (oral capsule)
40mg/packet : 1.68gm/packet (oral for suspension)
40mg : 1.1gm (oral capsule)
Santarus IncJun 15, 2004
- Reduction of risk of upper gastrointestinal bleeding in critically ill patients.
- Short term treatment of active benign gastric ulcer.
- Short-term treatment of active duodenal ulcer; treatment of heartburn and other symptoms associated with gerd; short-term treatment of erosive esophagitis; maintenance of healing of erosive esophagitis.
WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.
Felter's Materia Medica on Gastric Ulcer
CAMPHORA
A stearopten (having the nature of a ketone) derived from Cinnamomum Camphora. (Linné), Nees et Ebermeier (Nat. Ord. Lauraceae). China and... / ...the mucosa, and if applied strong may cause considerable irritation. In this manner it has produced gastric ulceration. In small doses camphor warms the stomach, stimulates secretion, increases perist... / ...due to gaseous distention of the stomach, or to nervous irritability. In occipital headache, from mental strain, or overstudy, small doses of 1
A stearopten (having the nature of a ketone) derived from Cinnamomum Camphora. (Linné), Nees et Ebermeier (Nat. Ord. Lauraceae). China and... / ...the mucosa, and if applied strong may cause considerable irritation. In this manner it has produced gastric ulceration. In small doses camphor warms the stomach, stimulates secretion, increases perist... / ...due to gaseous distention of the stomach, or to nervous irritability. In occipital headache, from mental strain, or overstudy, small doses of 1
CONIUM
The full grown fruit, gathered green, of Conium maculatum, Linné (Nat. Ord. Umbelliferae). Europe and Asia; naturalized in the United... / ...t relieves spasmodic neuralgia, neuralgia from carious teeth, ovarian neuralgia, and gastralgia. In gastric ulcer it is quite efficient and safe, while for relief of pain and to give rest it is a most... / ...be applied and be given to relieve pain even when a cure is not possible. It relieves the pain of swollen mammae during the menstrual periods a1
The full grown fruit, gathered green, of Conium maculatum, Linné (Nat. Ord. Umbelliferae). Europe and Asia; naturalized in the United... / ...t relieves spasmodic neuralgia, neuralgia from carious teeth, ovarian neuralgia, and gastralgia. In gastric ulcer it is quite efficient and safe, while for relief of pain and to give rest it is a most... / ...be applied and be given to relieve pain even when a cure is not possible. It relieves the pain of swollen mammae during the menstrual periods a1
CORNUSCOAC
The bark and root-bark of Cornus florida, Linné. (Nat. Ord. Cornaceae.) A beautiful flowering tree of the United States. Dose, 5 to 60 grains. Common Names: Dogwood,... / ...ble, relaxed tissues, with weak pulse and subnormal temperature. It has been suggested as useful in gastric ulcer. The preferred doses are from 5 to 20 drops.1
The bark and root-bark of Cornus florida, Linné. (Nat. Ord. Cornaceae.) A beautiful flowering tree of the United States. Dose, 5 to 60 grains. Common Names: Dogwood,... / ...ble, relaxed tissues, with weak pulse and subnormal temperature. It has been suggested as useful in gastric ulcer. The preferred doses are from 5 to 20 drops.1
GERANIUMGERAN
...cous diarrheas; chronic dysentery; diarrhoea with constant desire to defecate; passive hemorrhages; gastric ulcer. Action and Therapy.Geranium is one of the simple and much neglected of the early Ec......to quickly cure aphthous ulceration of the mouth attended by gastric acidity and acid diarrhea. For gastric ulcer it is one of the best therapeutic means we possess. Geranium, hydrastis, mangifera, bi...1
...cous diarrheas; chronic dysentery; diarrhoea with constant desire to defecate; passive hemorrhages; gastric ulcer. Action and Therapy.Geranium is one of the simple and much neglected of the early Ec......to quickly cure aphthous ulceration of the mouth attended by gastric acidity and acid diarrhea. For gastric ulcer it is one of the best therapeutic means we possess. Geranium, hydrastis, mangifera, bi...1
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.
Physician's Materia Medica on Gastric Ulcer
POTASSIUM BICHROMATE (Dichromate)
Alterative, antiseptic, moderately caustic. Prescribed in pro gressive spinal paralysis, gastric ulcer, some forms of dyspepsia and in aphonia; also applied locally in solution to warts, syphilitic vege tations, and as a remedy for fetid perspiration of the feet. Dose, 0.003 to 0.03 Grm. (1-20 to 1/2 gr.); applied in 5% solution for sweating feet; in 10% solution as a caustic.2
Alterative, antiseptic, moderately caustic. Prescribed in pro gressive spinal paralysis, gastric ulcer, some forms of dyspepsia and in aphonia; also applied locally in solution to warts, syphilitic vege tations, and as a remedy for fetid perspiration of the feet. Dose, 0.003 to 0.03 Grm. (1-20 to 1/2 gr.); applied in 5% solution for sweating feet; in 10% solution as a caustic.2
RESORCIN (Resorcinol)
A crystalline substance readily soluble in water. Antiseptic, analgesic, anti-emetic, hemostatic. Used internally in gastric ulcer. in fermentative diarrhea, in sea sickness, etc.; as a spray in whooping cough and hay fever; as a lotion in eczema and psoriasis. Dose, 0.12 to 0.30 Grm. (2 to 5 grs.) or more.2
A crystalline substance readily soluble in water. Antiseptic, analgesic, anti-emetic, hemostatic. Used internally in gastric ulcer. in fermentative diarrhea, in sea sickness, etc.; as a spray in whooping cough and hay fever; as a lotion in eczema and psoriasis. Dose, 0.12 to 0.30 Grm. (2 to 5 grs.) or more.2
SILVER NITRATE (Lunar Caustic)
In small doses has an alterative action; locally it is caustic in strong, astringent in dilute solutions; germicide. A valuable remedy in gastric ulcer and chronic gastric cat arrh and in ulceration of the intestines. When ulct-rations occur in the lower bowel, as also in chronic dysentery, injections of Silver Nitrate solution, about 1 grain to the fluidounce. are of great service. Locally, solutions of appropriate strength are used to abort felons, to prevent pitting in small pox; in treatment2
In small doses has an alterative action; locally it is caustic in strong, astringent in dilute solutions; germicide. A valuable remedy in gastric ulcer and chronic gastric cat arrh and in ulceration of the intestines. When ulct-rations occur in the lower bowel, as also in chronic dysentery, injections of Silver Nitrate solution, about 1 grain to the fluidounce. are of great service. Locally, solutions of appropriate strength are used to abort felons, to prevent pitting in small pox; in treatment2
WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.
Physician's Therapeutics Memoranda on Gastric Ulcer
GASTRIC ULCER
Nourish patient by enemas so that stomach may have complete rest. Internally, silver nitrate and resorcin with codeine or morph ine, antacids, especially sodium bicarbonate with bismuth subcar bonate; counter-irritation by tincture iodine or mustard leaves; antiemetics as needed; for hematemesis, emulsion of oil turpentine, antipyrin, alum or other styptic; suprarenal extract. Bowels must be regulated by enemata.2
Nourish patient by enemas so that stomach may have complete rest. Internally, silver nitrate and resorcin with codeine or morph ine, antacids, especially sodium bicarbonate with bismuth subcar bonate; counter-irritation by tincture iodine or mustard leaves; antiemetics as needed; for hematemesis, emulsion of oil turpentine, antipyrin, alum or other styptic; suprarenal extract. Bowels must be regulated by enemata.2
References
1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.