Mia: Medgend

Mia FDA Approved Drugs

AFREZZA [Insulin Recombinant Human]

12 units/inh (inhalation powder)

4 units/inh (inhalation powder)

8 units/inh (inhalation powder)

Mannkind^{Apr 17, 2015}

Administration of a composition comprising insulin complexed with a diketopiperazine..
Administration of a composition comprising insulin complexed with microparticles of a diketopiperazine..
Administration of fdkp microparticles comprising insulin..
Method of aerosolizing/deagglomerating an insulin dry powder for use in treating diabetes mellitus via oral inhalation using an inhaler with a cartridge containing the insulin dry powder..
Method of controlling glycemia in diabetics by administering an initial dose of insulin-fdkp with a meal; determining blood glucose level 1-2 hrs after and administering a supplemental dose of insulin-fdkp if postprandial glucose level is >140 mg/dl.
Method of delivering to a patient with diabetes mellitus in a single inhalation, greater than 75% of a dry powder dose comprising insulin and fumaryl diketopiperazine using a high resistance to flow dry powder inhaler..
Pulmonary administration of a compisition comprising insulin bound to a diketopiperazine..
Pulmonary administration of a composition comprising insulin bound to a complexing agent..
Pulmonary administration of an insulin composition comprising fdkp at the beginning of a meal to a patient also being treated with a long-acting insulin..
Treatment of a patient having diabetes mellitus with a prandial rapid acting insulin..
Treatment of diabetes mellitus with an inhaled insulin to improve glycemic control using a dry powder inhalation system comprising an inhaler, a cartridge and a dry powder medicament comprising insulin in a single inhalation.
Treatment of patient having diabetes mellitus via oral inhalation of fdkp microparticles comprising insulin.
Use of an inhaler to administer dry powder medicament.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

AGGRENOX [Aspirin^C₉H₈O₄ : Dipyridamole^{C₂₄H₄₀N₈O₄}]

25mg : 200mg (oral capsule, extended release)

Boehringer Ingelheim^{Nov 22, 1999}

To reduce the risk of stroke in patients who have had transient ischemia of the brain or completed ischemic stroke due to thrombosis.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

ANTARA (MICRONIZED) [Fenofibrate^{C₂₀H₂₁ClO₄}]

130mg (oral capsule)

43mg (oral capsule)

90mg (oral capsule)

Lupin Atlantis^{Nov 30, 2004}

Treating hypercholesterolemias with reduction of food effect.
Treating hypertriglyceridemias with reduction of food effect.
Treating primary hypercholesterolemia and mixed dyslipidemia.
Treating severe hypertriglyceridemia.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

BENDEKA [Bendamustine Hydrochloride^{C₁₆H₂₁Cl₂N₃O₂ClH}]

100mg/4ml (25mg/ml) (iv (infusion) solution)

Eagle Pharms^{Dec 7, 2015}

For the treatment of patients with chronic lymphocytic leukemia.
For the treatment of patients with indolent b-cell non-hodgkin lymphoma.
For use in the treatment of patients with chronic lymphocytic leukemia and/or non-hodgkins lymphoma.
For use in treatment of patients with chronic lymphocytic leukemia (cll) and/or non-hodgkin's lymphoma.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

BOSULIF [Bosutinib Monohydrate^{C₂₆H₂₉Cl₂N₅O₃H₂O}]

eq 100mg base (oral tablet)

eq 500mg base (oral tablet)

Pf Prism Cv^{Sep 4, 2012}

A method of treating a neoplasm.
A method of treating chronic myelogenous leukemia.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

CADUET [Amlodipine Besylate^{C₂₀H₂₅ClN₂O₅C₆H₆O₃S} : Atorvastatin Calcium]

eq 10mg base : eq 10mg base (oral tablet)

eq 10mg base : eq 20mg base (oral tablet)

eq 10mg base : eq 40mg base (oral tablet)

eq 10mg base : eq 80mg base (oral tablet)

eq 2.5mg base : eq 10mg base (oral tablet)

eq 2.5mg base : eq 20mg base (oral tablet)

eq 2.5mg base : eq 40mg base (oral tablet)

eq 5mg base : eq 10mg base (oral tablet)

eq 5mg base : eq 20mg base (oral tablet)

eq 5mg base : eq 40mg base (oral tablet)

eq 5mg base : eq 80mg base (oral tablet)

Pfizer^{Jan 30, 2004}

Treatment of hypertension and hyperlipidemia with a single composition.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

CALCITONIN-SALMON [Calcitonin Salmon^{C₁₄₅H₂₄₀N₄₄O₄₈S₂}]

200 iu/spray (nasal spray, metered)

Apotex Inc^{Nov 17, 2008}
Par Pharm^{Jun 8, 2009}

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

CLOLAR [Clofarabine^{C₁₀H₁₁ClFN₅O₃}]

20mg/20ml (1mg/ml) (iv (infusion) injectable)

Genzyme^{Dec 28, 2004}

Clolar is indicated for the treatment of pediatric patients 1 to 21 years old with relapsed or refractory acute lymphoblastic leukemia after at least two prior regimens.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

CRESTOR [Rosuvastatin Calcium^{2C₂₂H₂₇FN₃O₆SCa}]

10mg (oral tablet)

20mg (oral tablet)

40mg (oral tablet)

5mg (oral tablet)

Ipr^{Aug 12, 2003}

Treatment of pediatric patients 8 to 17 years of age with heterozygous familial hypercholesterolemia (hefh).
Use of rosuvastatin calcium for the primary prevention of cardiovascular disease in individuals without clinically evident coronary heart disease but with increased risk factors.
Use of rosuvastatin calcium to reduce elevated total-c, ldl-c, apob, nonhdl-c or tg levels; to increase hdl-c in adult patients with primary hyperlipidemia or mixed dyslipidemia; and to slow the progression of atherosclerosis..

efficacy
4.5 (2)

side effects
1.0 (1)

danger
1.0 (1)

CUBICIN [Daptomycin^{C₇₂H₁₀₁N₁₇O₂₆}]

500mg/vial (intravenous powder)

Cubist Pharms Llc^{Sep 12, 2003}

Treatment of the following infections: complicated skin and skin structure infections and staphylococcus aureus bloodstream infections (bacteremia) including those with right-sided infective endocarditis.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

CUBICIN RF [Daptomycin^{C₇₂H₁₀₁N₁₇O₂₆}]

500mg/vial (intravenous powder)

Cubist Pharms Llc^{Jul 6, 2016}

Treatment of the following infections: complicated skin and skin structure infections and staphylococcus aureus bloodstream infections (bacteremia) including those with right-sided infective endocarditis.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

EPANOVA [Omega-3-carboxylic Acids]

1gm contains at least 850mg of polyunsaturated fatty acids (oral capsule)

Astrazeneca Pharms^{May 5, 2014}

Treatment of hypertriglyceridemia.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

FENOGLIDE [Fenofibrate^{C₂₀H₂₁ClO₄}]

120mg (oral tablet)

40mg (oral tablet)

Santarus Inc^{Aug 10, 2007}

For reducing total cholesterol (total-c), ldl-c, apo-lipoprotein b, or total triglycerides, and treating hypertriglyceridemia.
Use of fenofibrate for reducing elevated total cholesterol (total-c), ldl-c, apo-lipoprotein b, or total triglycerides.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

FIBRICOR [Fenofibric Acid^{C₁₇H₁₅ClO₄}]

105mg (oral tablet)

35mg (oral tablet)

Aralez Pharms Inc^{Aug 14, 2009}

Adjunctive therapy to diet in patients with elevated cholesterol and/or lipid levels.
Adjunctive therapy to diet in patients with hyperlipidemias.
Adjunctive therapy to diet in patients with mixed dyslipidemia.
Adjunctive therapy to diet to patients with hypertriglyceridemia.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

GLUCOTROL XL [Glipizide^{C₂₁H₂₇N₅O₄S}]

10mg (oral tablet, extended release)

2.5mg (oral tablet, extended release)

Pfizer^{Apr 26, 1994}

Method of treating hyperglycemia to improve glycemic control in a patient by oral admin of once a day osmotic dosage form of glipizide with polyethylene oxide, hydroxypropylmethylcellulose, cellulose acetate, and sodium chloride.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

ICLUSIG [Ponatinib Hydrochloride^{C₂₉H₂₇F₃N₆OClH}]

eq 15mg base (oral tablet)

eq 30mg base (oral tablet)

eq 45mg base (oral tablet)

Ariad^{Dec 14, 2012}

A method for the treatment of leukemias.
A method for treating acute lymphoblastic leukemia.
A method for treating chronic myeloid leukemia.
A method for treating leukemia resulting from a mutation in the bcr-abl kinase domain.
A method for treating philadelphia chromosome positive acute lymphoblastic leukemia.
A method of treating chronic myelogenous leukemia.

efficacy
0.0 (0)

side effects
0.0 (0)

danger
0.0 (0)

IMBRUVICA [Ibrutinib^{C₂₅H₂₄N₆O₂}]

140mg (oral capsule)

Pharmacyclics Inc^{Nov 13, 2013}

For the treatment of patients with waldenstrom's macroglobulinemia.
Treatment for chronic lymphocytic leukemia with 17p deletion.
Treatment of chronic lymphocytic leukemia.
Treatment of mantle cell lymphoma.
Treatment of marginal zone lymphoma.
Treatment of small lymphocytic lymphoma.
Treatment of waldenstrom's macroglobulinemia.

efficacy
0.0 (0)

side effects
0.0 (0)

JAKAFI [Ruxolitinib Phosphate^{C₁₇H₁₈N₆H₃O₄P}]

eq 10mg base (oral tablet)

eq 15mg base (oral tablet)

eq 20mg base (oral tablet)

eq 25mg base (oral tablet)

eq 5mg base (oral tablet)

Incyte Corp^{Nov 16, 2011}

For the treatment of intermediate or high-risk myelofibrosis.
For the treatment of polycythemia vera.
Use of ruxolitinib (jakafi) for blocking signal transduction of janus associated kinases (jaks) jak1 and/or jak2.
Use of ruxolitinib (jakafi) for inhibiting janus associated kinases (jaks) jak1 and/or jak2..

JUXTAPID [Lomitapide Mesylate^{C₃₉H₃₇F₆N₃O₂CH₄O₃S}]

eq 10mg base (oral capsule)

eq 20mg base (oral capsule)

eq 30mg base (oral capsule)

eq 40mg base (oral capsule)

eq 5mg base (oral capsule)

eq 60mg base (oral capsule)

Aegerion^{Dec 21, 2012}

A dosing regimen for the treatment of hypercholesterolemia and hyperlipidemia in patients with homozygous familial hypercholesterolemia using at least three step-wise increasing doses.
A dosing regimen for the treatment of hypercholesterolemia and hyperlipidemia in patients with homozygous familial hypercholesterolemia using at least three step-wise increasing doses.
Treatment of hypercholesterolemia by decreasing the amount or activity of microsomal triglyceride transfer protein in patients with homozygous familial hypercholesterolemia.
Treatment of hypercholesterolemia, hyperlipidemia and hyperlipoproteinemia in patients with homozygous familial hypercholesterolemia.

KUVAN [Sapropterin Dihydrochloride^{C₉H₁₅N₅O₃2ClH}]

100mg (oral tablet)

100mg/packet (oral powder)

500mg/packet (oral powder)

Biomarin Pharm^{Dec 13, 2007}

For reducing blood phenylalanine levels in a human suffering from hyperphenylalaninemia.
Method of use for reducing blood phenylalanine levels in a human suffering from hyperphenylalaninemia.
To reduce blood phenylalanine (phe) levels in patinets with hyperphenylalaninemia (hpa).
To reduce blood phenylalanine levels in patients with hyperphenylalaninemia due to tetra hydrobiopterin responsive phenylketonuria. kuvan should be taken orally with food to increase absorption.

KYNAMRO [Mipomersen Sodium^{C₂₃₀H₃₀₅N₆₇O₁₂₂P₁₉S₁₉1₉Na}]

200mg/ml (200mg/ml) (subcutaneous solution)

Kastle Theraps Llc^{Jan 29, 2013}

Adjunctive therapy to lipid-lowering medications and diet to reduce low density lipoprotein-cholesterol, apolipoprotein b, total cholesterol, and non-high density lipoprotein cholesterol in pts with homozygous familial hypercholesterolemia.

LIVALO [Pitavastatin Calcium^{2C₂₅H₂₃FNO₄Ca}]

eq 1mg base (oral tablet)

eq 2mg base (oral tablet)

eq 4mg base (oral tablet)

Kowa Co^{Aug 3, 2009}

Adjuncitve therapy to diet to reduce elevated total cholesterol, low-density lipoprotein cholesterol, apolipoprtein b, triglycerides and to increase hdl-c in adult patients with primary hyperlipidemia or mixed dyslipidemia.

MARQIBO KIT [Vincristine Sulfate^{C₄₆H₅₆N₄O₁₀H₂O₄S}]

5mg/5ml (1mg/ml) (intravenous injectable, liposomal)

Talon Therap^{Aug 9, 2012}

Treatment of adult patients with philadelphia chromosome-negative(ph-) acute lymphoblastic leukemia (all) in second or greater relapse or whose disease has progressed following two or more anti-leukemia therapies.

MIACALCIN [Calcitonin Salmon^{C₁₄₅H₂₄₀N₄₄O₄₈S₂}]

200 iu/ml (injection injectable)

Mylan Ireland Ltd^{Mar 29, 1991}

MYCAMINE [Micafungin Sodium^{C₅₆H₇₀N₉O₂₃SNa}]

eq 100mg base/vial (iv (infusion) injectable)

eq 50mg base/vial (iv (infusion) injectable)

Astellas^{Jun 27, 2006}

Treatment of esophageal candidiasis and prophylaxis of candida infections in hsct patients.
Treatment of patients with candidemia, acute disseminated candidiasis, candida peritonitis and abscesses.

NIASPAN [Niacin^{C₆H₅NO₂}]

1gm (oral tablet, extended release)

500mg (oral tablet, extended release)

750mg (oral tablet, extended release)

Abbvie^{Jul 28, 1997}

A method of reducing the capacity of extended release nicotinic acid to provoke a flushing reaction by pretreating an individual with a flush inhibiting agent prior to the administration of the extended release nicotinic acid.
Method of treating hyperlipidemia with nicotinic acid by dosing once per day in the evening or at night.
Reduction in elevated tc and ldl-c by dosing once per day in the evening or at night, with pretreatment with a flush inhibitin agent such as aspirin.
Reduction in elevated tc and ldl-c by dosing once per day in the evening or at night.
Reduction in risk of recurrent nonfatal myocardial infarction by dosing once per day in the evening or a t night, with pretreatment with a flush inhibitin agent such as aspirin.
Reduction in risk of recurrent nonfatal myocardial infarction by dosing once per day in the evening or at night.
Reduction in tg by dosing once per day in the evening or at night, with pretreatment with a flush inhibiting agent such as aspirin.
Reduction in tg by dosing once per day in the evening or at night.
Treatment of primary and mixed dyslipidemia by dosing once per day in the evening or at night, with pretreatment with a flush inhibiting agent such as aspirin.
Treatment of primary and mixed dyslipidemia by dosing once per day in the evening or at night.

ORFADIN [Nitisinone^{C₁₄H₁₀F₃NO₅}]

10mg (oral capsule)

20mg (oral capsule)

2mg (oral capsule)

4mg/ml (oral suspension)

5mg (oral capsule)

Swedish Orphan^{Jan 18, 2002}

PROMACTA [Eltrombopag Olamine^{C₂₅H₂₂N₄O₄2C₂H₇NO}]

eq 100mg acid (oral tablet)

eq 12.5mg acid (oral tablet)

eq 25mg acid (oral tablet)

eq 25mg acid/packet (oral for suspension)

eq 50mg acid (oral tablet)

eq 75mg acid (oral tablet)

Novartis Pharms Corp^{Nov 16, 2012}

Patients with severe aplastic anemia who have had an insufficient response to immunosuppressive therapy.
Topical treatment of interdigital tinea pedis and tinea corporis due to trichophyton rubrum, trichophyton mentagrophytes or epidermophyton floccosum.
Treatment of idiopathic thrombocytopenic purpura (itp).
Treatment of immune (idiopathic) thrombocytopenia (itp).
Treatment of thrombocytopenia in adult and pediatric patients 6 years and older with chronic immune (idiopathic) thrombocytopenia (itp).
Treatment of thrombocytopenia in patients with chronic hepatitis c to allow the initiation and maintenance of interferon-based therapy.

QSYMIA [Phentermine Hydrochloride^{C₁₀H₁₅NClH} : Topiramate^{C₁₂H₂₁NO₈S}]

eq 11.25mg base : 69mg (oral capsule, extended release)

eq 15mg base : 92mg (oral capsule, extended release)

eq 3.75mg base : 23mg (oral capsule, extended release)

eq 7.5mg base : 46mg (oral capsule, extended release)

Vivus^{Jul 17, 2012}

Use of qsymia (phentermine and topiramate) for weight management, including, but not limited to effecting weight loss, treating obesity, and/or treating overweight.

REVLIMID [Lenalidomide^{C₁₃H₁₃N₃O₃}]

10mg (oral capsule)

15mg (oral capsule)

2.5mg (oral capsule)

20mg (oral capsule)

25mg (oral capsule)

Celgene^{Dec 27, 2005}

Treatment of male patient having a disease or condition responsive to a teratogenic drug.
Use of revlimid (lenalidomide) for the treatment of mantle cell lymphoma (mcl).
Use of revlimid (lenalidomide) for the treatment of multiple myeloma and transfusion-dependent anemia in myelodysplastic syndromes (mds).
Use of revlimid (lenalidomide) for the treatment of multiple myeloma.
Use of revlimid (lenalidomide) for the treatment of transfusion-dependent anemia in myelodysplastic syndromes (mds).
Use of revlimid (lenalidomide) to inhibit the secretion of pro-inflammatory cytokines, including tumor necrosis factor alpha.
Use of revlimid (lenalidomide) while preventing the exposure of a fetus or other contraindicated individual to revlimid (lenalidomide).

RYANODEX [Dantrolene Sodium^{2C₁₄H₉N₄O₅2Na7H₂O}]

250mg/vial (intravenous for suspension)

Eagle Pharms^{Jul 22, 2014}

For use in the treatment of malignant hyperthermia in conjunction with appropriate supportive measures and for the prevention of malignant hyperthermia in patients at high risk..

RYDAPT [Midostaurin^{C₃₅H₃₀N₄O₄}]

25mg (oral capsule)

Novartis Pharms Corp^{Apr 28, 2017}

Treatment of adult patients with aggressive systemic mastocytosis (asm), systemic mastocytosis with associated hematological neoplasm (sm-ahn), or mast cell leukemia (mcl).
Treatment of adult patients with newly diagnosed acute myeloid leukemia (aml) who are flt3 mutation-positive, in combination with standard cytarabine and daunorubicin induction and cytarabine consolidation chemotherapy.

SAMSCA [Tolvaptan^{C₂₆H₂₅ClN₂O₃}]

15mg (oral tablet)

30mg (oral tablet)

Otsuka America Pharm^{May 19, 2009}

Method of treating hyponatremia.

SENSIPAR [Cinacalcet Hydrochloride^{C₂₂H₂₂F₃NClH}]

eq 30mg base (oral tablet)

eq 60mg base (oral tablet)

eq 90mg base (oral tablet)

Amgen^{Mar 8, 2004}

Method of decreasing or reducing parathyroid hormone level; method of modulating parathyroid hormone secretion;method of treating hyperparathyroidism; method of reducing serum ionized calcium level.
Method of treating hyperparathyroidism; method of treating hypercalcemia.

SPRYCEL [Dasatinib^{C₂₂H₂₆ClN₇O₂SH₂O}]

100mg (oral tablet)

140mg (oral tablet)

20mg (oral tablet)

50mg (oral tablet)

70mg (oral tablet)

80mg (oral tablet)

Bristol Myers Squibb^{May 30, 2008}

A method for the treatment of a protein tyrosine kinase-associated disorder.
A method for the treatment of cancer.
A method for treatment of a cancer, wherein the cancer is chronic myelogenous leukemia.

SYMLIN [Pramlintide Acetate^{C₁₇₁H₂₆₇N₅₁O₅₃S₂C₂H₄O₂H₂O}]

eq 1.5mg base/1.5ml (eq 1mg base/ml) (subcutaneous injectable)

eq 2.7mg base/2.7ml (eq 1mg base/ml) (subcutaneous injectable)

Astrazeneca Ab^{Sep 25, 2007}

Treatment of diabetes with an amylin agonist, including with insulin.
Treatment of diabetes with an amylin agonist.
Use of an amylin agonist to reduce gastric motility and treat post prandial hypergylcemia.

SYNRIBO [Omacetaxine Mepesuccinate^{C₂₉H₃₉NO₉}]

3.5mg/vial (subcutaneous powder)

Teva Pharms Intl^{Oct 26, 2012}

Treatment of leukemia.
Treatment of patients with tyrosine kinase inhibitor (tki) resistant or intolerant chronic myeloid/myelogenous leukemia (cml).

TASIGNA [Nilotinib Hydrochloride Monohydrate^{C₂₈H₂₂F₃N₇OClHH₂O}]

eq 150mg base (oral capsule)

eq 200mg base (oral capsule)

Novartis^{Jun 17, 2010}

A method for the treatment of leukemias.
Treatment of newly diagnosed philadelphia chromosome positive chronic myeloid leukemia (ph + cml).
Treatment of philadelphia chromosome positive chronic myeloid leukemia (ph+cml).

TREANDA [Bendamustine Hydrochloride^{C₁₆H₂₁Cl₂N₃O₂ClH}]

100mg/vial (iv (infusion) powder)

180mg/2ml (90mg/ml) (iv (infusion) solution)

25mg/vial (iv (infusion) powder)

45mg/0.5ml (90mg/ml) (iv (infusion) solution)

Cephalon^{Mar 20, 2008}

For use in the treatment of patients with chronic lymphocytic leukemia (cll) and/or indolent b-cell non-hodgkin lymphoma (nhl).
For use in the treatment of patients with chronic lymphocytic leukemia (cll).
For use in the treatment of patients with chronic lymphocytic leukemia and/or non-hodgkins lymphoma.
For use in the treatment of patients with indolent b-cell non-hodgkin lymphoma.

TRICOR [Fenofibrate^{C₂₀H₂₁ClO₄}]

145mg (oral tablet)

48mg (oral tablet)

Abbvie^{Nov 5, 2004}

Adjunctive therapy to diet in adults to reduce ldl-c, total-c, triglycerides and apo b, and increase hdl-c in patients with primary hypercholesterolemia or mixed dyslipidemia (types iia, iib) and to treat hypertriglyceridemia (types iv, v).
Adjunctive therapy to diet in adults to reduce ldl-c, triglycerides and apo b, and increase hdl-c in patients with primary hypercholesterolemia or mixed dyslipidemia (types iia, iib) and to treat hypertriglyceridemia (types iv, v).

TRIGLIDE [Fenofibrate^{C₂₀H₂₁ClO₄}]

160mg (oral tablet)

Skyepharma Ag^{May 7, 2005}

A method of treating dyslipidemia and dyslipoproteinemia using a dosage form that can provide an effective amount of fenofibrate to a patient in a fasted state which is at least 90% of the auc amount provided by the dosage form.

TRISENOX [Arsenic Trioxide^As₂O₃]

1mg/ml (injection injectable)

Cephalon^{Sep 25, 2000}

Treatment of acute promyelocytic leukemia (apl) in patients whose apl is characterized by the presence of the (15;17) translocation or pml/rar-alpha gene expression.
Treatment of acute promyelocytic leukemia (apl).
Treatment of acute promyelogenous leukemia (apl).

ULORIC [Febuxostat^{C₁₆H₁₆N₂O₃S}]

40mg (oral tablet)

80mg (oral tablet)

Takeda Pharms Usa^{Feb 13, 2009}

Chronic management of hyperuricemia in patients with gout. not recommended for the treatment of asymptomatic hyperuricemia.
Use of febuxostat for the management of hyperuricemia in patients suffering from gout and, when used with theophylline without the need for dose adjustment of theophylline.

VAPRISOL IN 5% DEXTROSE IN PLASTIC CONTAINER [Conivaptan Hydrochloride^{C₃₂H₂₆N₄O₂ClH}]

20mg/100ml (0.2mg/ml) (iv (infusion) injectable)

Cumberland Pharms^{Oct 8, 2008}

Method of using antagonist of arginine vasopressin (ava) v1a and v2 receptors for intravenous treatment of patients with euvolemic hyponatremia.
Method of using antagonist of arginine vasopressin (ava) v1a and v2 receptors for intravenous treatment of patients with hypervolemic hyponatremia.

VASCEPA [Icosapent Ethyl^{C₂₂H₃₄O₂}]

1gm (oral capsule)

500mg (oral capsule)

Amarin Pharms^{Jul 26, 2012}

Method of reducing tg levels in patient on statin therapy suffering from severe hypertriglyceridemia.
Method of reducing tg levels in patient suffering from severe hypertriglyceridemia.

VELTASSA [Patiromer Sorbitex Calcium^{2(C₁₀H₁₀)n(C₈H₁₄)nC₆H₁₄O₆(C₃H₂FO₂)nCa}]

eq 16.8gm base/packet (oral powder)

eq 25.2gm base/packet (oral powder)

eq 8.4gm base/packet (oral powder)

Relypsa Inc^{Oct 21, 2015}

Treatment of hyperkalemia.

VENCLEXTA [Venetoclax^{C₄₅H₅₀ClN₇O₇S}]

100mg (oral tablet)

10mg (oral tablet)

50mg (oral tablet)

Abbvie Inc^{Apr 11, 2016}

Treatment of patients with chronic lymphocytic leukemia (cll) with 17p deletion, as detected by an fda approved test, who have received at least one prior therapy.

ZETIA [Ezetimibe^{C₂₄H₂₁F₂NO₃}]

10mg (oral tablet)

Msd Intl Gmbh^{Oct 25, 2002}

Reduction of elevated plasma sterol and/or stanol levels in a mammal.
To reduce elevated total-c, ldl-c, apo b and non-hdl-c in patients with primary hyperlipidemia by administration of ezetimibe alone or in combination with a statin or with fenofibrate.
To reduce plasma cholesterol levels in a mammal.

ZOMETA [Zoledronic Acid^{C₅H₁₀N₂O₇P₂H₂O}]

eq 4mg base/100ml (iv (infusion) injectable)

eq 4mg base/5ml (iv (infusion) injectable)

Novartis^{Jun 17, 2011}

Bone metastases.
Hypercalcemia of malignancy.
Multiple myeloma.

ZURAMPIC [Lesinurad^{C₁₇H₁₄BrN₃O₂S}]

200mg (oral tablet)

Ironwood Pharms Inc^{Dec 22, 2015}

Achieving a therapeutic benefit in a subject with gout.
Coadministering with allopurinol to reduce serum uric acid (sua) below 4 mg/dl; below 6mg/dl in patients having uric acid deposits; and/or below 6mg/dl with sua intraday change more than 50% and/or adverse event rate less than 15%.
Reduction of serum uric acid levels.
Treatment of gout.
Treatment of hyperuricemia.

ZYDELIG [Idelalisib^{C₂₂H₁₈FN₇O}]

100mg (oral tablet)

150mg (oral tablet)

Gilead Sciences Inc^{Jul 23, 2014}

A method of disrupting leukocyte function, including as an inhibitor of pi3kdelta kinase.
For the treatment of patients with cll, fl, or sll.
For the treatment of patients with relapsed chronic lymphocytic leukemia.
For the treatment of patients with relapsed follicular b-cell non-hodgkin lymphoma or [relapsed] small lymphocytic lymphoma.
In combination with rituximab, for the treatment of patients with relapsed chronic lymphocytic leukemia (cll).
Inhibition on pi3k kinase.

WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.

WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Felter's Materia Medica on Mia

ACONITUM NEPALLUS
The dried tuberous root of Aconitum Napellus, Linné (Nat. Ord. Ranunculaceae). Mountains of Europe and Asia, and northwestern North America.... / ...dication. Irritation of mucous membranes with vascular excitation and determination of blood; hyperemia; chilly sensations; skin hot and dry, with small, frequent pulse. Early stage of fevers with or ... / ...approaching from the extremities to the body. Excessive sweating comes on, rapidly lowering the body temperature, dimness of vision, ¹

ADONIS VERNALIS
The whole plant of Adonis vernalis, Linné. (Nat. Ord. Ranunculaceae). Southern Europe, Siberia, and Labrador. Dose, 1/2 to 3 grains. Common Name:... / ... in which for some reason it is undesirable to employ them. It is especially commended where arryrthmia with feeble cardiac force and dyspnoea and dropsy are present. It has long been a popular remedy... / ...in epilepsy, administering it with bromide of potassium. It should not be given when there is gastro-intestinal irritation or inflammation. ¹

ALOE^ALOE
The dried juice of the leaves of several species of Aloe: (1) Aloe Perryi, Baker; (2) Aloe vera, Linné; (3) Aloe ferox, Miller. (Nat. Ord.... / ... the best of these is the Lapactic pill. When sulphate of iron is indicated in chlorosis and anemia, aloes is generally combined with it. It has the effect of restraining the constipating action o...¹

ARNICA MONTANA
The dried flower-heads of Arnica montana, Linné (Nat. Ord. Compositae). A perennial of Siberia and the cooler parts of Europe; also found in... / ..., it often proves the needed stimulant and antihydrotic. Arnica is a stimulant of great power in anemia, with weak heart and capillary feebleness, and marked depression, diarrhoea and dropsy, but no i...¹

ASCLEPIAS TUBEROSA
The root of Asclepias tuberosa, Linné (Nat. Ord. Asclepiadaceae). United States and Canada. Dose, 5 to 60 grains. Common Names: Pleurisy Root,... / ...epias slows the action of the heart and lowers arterial tension. It especially relieves local hyperemia by vaso-motor control. Through some unexplained, though probably circulatory regulating action u...¹

BAPTISIA
The recent root and leaves of Baptisia tinctoria, Robert Brown (Nat. Ord. Leguminosae), a perennial shrub-like plant, indigenous to North... / ...eeblement and tendency to ulceration-in fact, a condition of atony. It is contraindicated by hyperaemia; indicated by capillary stasis. Baptisia is important for its influence upon typhoid conditions.... / ...healing of the ulcerated surfaces. In all of the local disorders mentioned, baptisia should be given internally as well as applied locally.¹

BERBERIS (Mahonia) AQUIFOLIUM
The root of Berberis aquifolium, Pursh (Nat. Ord. Berberidaceae). Western United States from Colorado to the Pacific coast; cultivated also for... / ...pain of syphilitic periostitis. Syphilitic phagedena disappears under its use, and sometimes the anemia of syphilis yields to its nutritional improvement. It should be given freely in syphilitic leuco...¹

BERBERIS VULGARIS
The bark of the root and the berries of Berberis vulgaris, Linné (Nat. Ord. Berberidaceae). Europe, Asia, and the United States. Common Names:... / ...ly used in domestic medicine for sore eyes, and later by practitioners for chronic catarrhal ophthalmias. The decoction is employed for this purpose, and is equally efficient in aphthous sore mouth. I... / ...of calculi, small doses may be given when there is burning and soreness and excess of mucus in the urinary tract.¹

BUCHU (Barosma)^AGBE2
The dried leaves of (1) Barosma betulina (Thunberg), Bartling and Wendland, or of (2) Barosma serratifolia (Curtis), Willdenow. (Nat. Ord.... / ...r these circumstances it may be given in chronic cystitis, pyelitis, urethritis, prostatitis, lithaemia, and chronic vesical irritation. For catarrh of the bladder it is frequently effective, and in l... / ...have far better remedies. Buchu renders the urine dark, the latter depositing a brownish precipitate. It should never be used in acute disorders.¹

CACTUS (Selenicereus spp.)
The fresh, green stems and the flowers of Selenicereus grandiflorus (L.) Britt. & Rose (and other Selenicereus speciesMM) (Cereus grandiflorus,... / ...s an intense irritant to the cardiac ganglia, producing thereby irritability, hyperaesthesia, arrythmia, spasm and neuralgia of the heart, and even carditis and pericarditis. According to E. M. Hale, ... / ...organ were held with a strong band, it is often the most prompt of all cardiac remedies. It is a good remedy in the heart troubles produced by to¹

CAFFEA
...eeble circulation, with threatened heartfailure; sense of exhaustion; headache, with cerebral hyperemia or congestion. Action.Coffee is a decided cerebral stimulant and energizer. It also increases ......ck of delirium tremens. Coffee is a gratefully refreshing agent for headache due to cerebral hyperaemia or congestion, as shown by red face and injected eyes, but will be likely to aggravate a neuralg...¹

CALUMBA (Jateorhiza palmata)^JAPA2
The root of Jateorhiza palmata (Lamarck), Miers (Nat. Ord. Menispermaceae). A climbing perennial, the Kalumb of the Southeast coast of Africa. Dose, 1 to 30 grains. Common Names:... / ...directly, by favoring better digestion, the quality of the blood is improved, hence its value in anemia during convalescence.¹

CAMPHORA
A stearopten (having the nature of a ketone) derived from Cinnamomum Camphora. (Linné), Nees et Ebermeier (Nat. Ord. Lauraceae). China and... / ...ng warmth, redness, and sometimes itching. Slight anesthesia follows. It causes smarting and hyperaemia of the mucosa, and if applied strong may cause considerable irritation. In this manner it has pr... / ...due to gaseous distention of the stomach, or to nervous irritability. In occipital headache, from mental strain, or overstudy, small doses of ¹

CANNABIS
The dried flowering tops of the female plant of Cannabis sativa, Linné, or the variety indica, Lamarck (Nat. Ord. Cannabinaceae). Asia, East... / ...s; spasmodic and painful conditions, with depression; mental illusions; hallucinations; cerebral anemia from spasm of cerebral vessels; palpitation of the heart, with sharp, stitching pain; and menstr... / ...of the urino-genital tract and relieves pain. For the first condition it is invaluable in more or less painful conditions in which opium see¹

CANTHARIS
The dried beetles, Cantharis vesicatoria (Linné), De Geer. (Ord. Coleoptera.) Southern Europe. Dose, 1 grain. Common Name: Spanish Fly; Synonym:... / ...nd acute inflammation of the kidneys and bladder; with final suppression of urine and death from uremia. Intense burning pain, soreness and tenderness of the abdomen, excessive burning thirst, profuse...¹

Physician's Materia Medica on Mia

AMERICAN HELLEBORE
The rhizome and root of VERATRUM VIRIDE, Solander. Cardiac - depressant. having remarkable power to reduce the pulse in fever. Its most- important use is in controlling blood pressure in aortic an eurism, in cerebral hyperemia and in certain heart affections. Apt to cause nausea unless combined with an opiate. Produces best ef fects when doses are frequently repeated. Dose 0.06 to 0.2 Grm. (1 to 3 grs-).²

CANNABIS INDICA (Indian Cannabis)
The flowering tops of the pistillate plant of CANNABIs sa'r1vA, Lin., grown in the East Indies. Antispasmodic, analgesic, deliriant. aphrodisiac. Locally applied it is anti-pruritic. Prescribed in teta nus, in neuralgia, in insomnia and other conditions depending on anemia of the brain, in combating the morphine habit, etc. Dose, 0.2 to 0.6 Grm. (3 to 10 grs.) or more.²

DAMIANA^TUDI
The leaves of TURNERA DIFFUSA APHRODISIACA, (Ward) Urb. Tonic, stimulant diuretic, laxative, reputed aphrodisiac.²

MOUNTAIN LAUREL^KALA
The leaves of KALMIA LATIFOLIA, Lin. A sedative poison. In small doses antipyretic, alterative, anti-syphilitic, cardiac sedative, astringent. Prescribed in febrile conditions, in chronic diarrhea and as a general alterative.²

NARGOL (Silver Nucleinate)
A preparation having properties resembling those of Silver Nitrate. q. v. Chiefly used in the treatment of gonorrhea, and of ophthalmias due to gonorrheal infection. Urethral injections may be of the strength of1 to4 grs. to the ounce (1/4 to 1 per cent.), in acute cases.²

SODIUM CACODYLATE
Contains arsenic, and accordingly is alterative and germicidal although scarcely poisonous. Used in tuberculosis, obstinate psoriasis, glycosuria and pseudo-leukemia. Dose, 0.06 to 0.30 Grm. (1 to 5 grs.).²

WILD INDIGO (Baptisia)^BAPTI
The root of BAPTISIA TINCTORIA, (L.) R. Br. Alterative, hepatic stimulant, emetic, cathartic, antiseptic; used with advantage in typhoid conditions and septicemia; topically applied to foul, irritable and painful ulcers, and wherever there are fetid discharges.²

Physician's Therapeutics Memoranda on Mia

ABORTION
Habitual abortion may be due to syphilis, to endo-metritis or uterine displacement. to undue sexual excitement... / Habitual abortion may be due to syphilis, to endo-metritis or uterine displacement. to undue sexual excitement or to anemia or other form of malnutrition. Prevention of the accident in such cases depends upon recognizing and removing the cause. The patient must be given... / ...al ways be used with proper caution, and only a physiologically stand ardized preparation should be employed.²

AMBLYOPIA
Ascertain the cause. If due... / ...to constitutional taint, use altera tives. notably potassium iodide. If from extreme debility, appropri ate tonils, especially strychnine; if from uremia, Tonic Pilocarpine Compound; if from auto-intoxication, a mercurial purge; ii from ex cess, Eupeptic Hypophosphites. glycerophosphates, strychnine...²

AMENORRHEA
When due to anemia and debility, combinations of aloes with iron, In an otherwise healthy subject, apiol or the essential oil of penny. royal or of rue, savine or... / When due to anemia and debility, combinations of aloes with iron, In an otherwise healthy subject, apiol or the essential oil of penny. royal or of rue, savine or ta... / ...hot infusions of pennyroyal or similar herbs; quinine with aloes or rhubarb. Cotton-root bark, ergot and similar agents are to be used always with due caution.²

ANEMIA
Nourishing and easily digested food with remedies for promoting digestion and overcoming a tendency to constipation may often ac complish more than hematinics. Of these iron (as reduced iron or ferrous carbonate) is most often prescribed, but in many cachectic conditions is inferior to arsenic or mercury (in minute doses). Among the most eflicient preparations are Solution Gold and Arsenic Bro mide, N., B. & Co., Haemo-Mangan with Arsenic, and formulas in which iron is combined with manganese, o...²

ECZEMA
Improve general health of patient by hygienic measures. See that the diet is simple and... / ... Fats, salted meats, pastry and all indigestible articles of food must be interdicted. See that the excretory functions are properly performed. If anemia or de bility or any constitutional taint is present, treat on general princi ples. In early stages, apply zinc ointment or zinc oxide or oleate as...²

EPILEPSY
During the seizure, amyl nitrite is the remedy most likely to be of service; chloroform must be... / ... well diluted, after meals. beginning with 10 grain doses and increasing to 25 or 30 grs., provided it does not disturb the digestion. If there is anemia, Combine with ferrous bromide or with Solution Gold and Arsenic Bmmides, N., B. & Co. Bromides of sodium and ammonium may be often advantage ously... / ...hydrate. In children, ascertain whether the irritation is due to worms and treat accordingly.²

GANGRENE
Bromine is the most e lcient escharotic; chromic acid and nitric acid are often used. Carbolic acid applied in full strength, followed by alcohol to limit its action, with subsequent dressing with Iodosyl has given excellent results. For cleansing, hydrogen peroxide is eflicient. Ichthyol and boric acid may be used in dressing, but Iodosyl is better. Internally guaiacol and creosote to guard against p yemia.²

LITHEMIA
To eliminate uric acid use Lithiated Ze-an. The patient should drink much water.²

NEPHRITIS, ACUTE
Prescribe at first aconite, calomel and sodium bicarbonate fol lowed by a saline cathartic; warm mucilaginous drinks, potassium citrate and Ze-an; Glyceroplasma over loins. If uremia is threaten ed, elaterium, Tonic Pilocarpine Compound, hot air baths to cause sweating. In later stages digitalis and squill, caffeine, compound spirit juniper, even cantharides in small doses.²

PYEMIA
Antistreptococcic serum promises more than any other remedy; resorcin, Iodosyl, boric acid, ferric chloride have proved of service.²

UREMIA
Promote elimination by skin and bowels; Tonic Pilocarpine Com pound, N., B. & Co. with the hot pack for the former; elaterium for the latter. For convulsions, chloral and bromides (Bromanodyne) or chloroform (by inhalation). Vt!ut3S€3Ctl()n must be considered, with the alternative of intravenous injection of normal salt solution.²

References

1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.

Ledgend of Medicine

MODERN MEDICINES

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RANDOM DRUGS

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Mia FDA Approved Drugs

Felter's Materia Medica on Mia

Physician's Materia Medica on Mia

Physician's Therapeutics Memoranda on Mia

References