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Neuralgia

Trigeminal neuralgia (TN) is a type of chronic pain that affects your face. It causes extreme, sudden burning or shock-like pain. It usually affects one side of the face. Any vibration on your face, even from talking, can set it off. The condition may come and go, disappearing for days or even months. But the longer you have it, the less often it goes away.

TN usually affects people over 50, especially women. The cause is probably a blood vessel pressing on the trigeminal nerve, one of the largest nerves in the head. Tumors and multiple sclerosis can also cause TN, but in some cases the cause is unknown.

There is no specific test for TN. It can be hard to diagnose, since many other conditions can cause facial pain. Treatment options include medicines, surgery, and complementary techniques.

NIH: National Institute of Neurological Disorders and Stroke

Neuralgia FDA Approved Drugs

GRALISE [GabapentinC9H17NO2]
RX
-
300mg (oral tablet)
600mg (oral tablet)
Depomed IncJan 28, 2011
  • Treatment with gabapentin, including treatment of neuropathic pain, including neuropathic pain associated with postherpetic neuralgia.
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

HORIZANT [Gabapentin EnacarbilC16H27NO6]
RX
-
300mg (oral tablet, extended release)
600mg (oral tablet, extended release)
Arbor Pharms LlcDec 13, 2011
  • Management of postherpetic neuralgia (phn) in adults.
  • Treatment of moderate-to-severe primary restless leg syndrome in adults.
efficacy
0.0  (0)
side effects
0.0  (0)
danger
0.0  (0)

UNK

LYRICA [PregabalinC8H17NO2]
RX
-
100mg (oral capsule)
150mg (oral capsule)
200mg (oral capsule)
20mg/ml (oral solution)
225mg (oral capsule)
300mg (oral capsule)
75mg (oral capsule)
Pf Prism CvDec 30, 2004
  • Management of fibromyalgia.
  • Treatment of pain, including neuropathic pain associated with diabetic peripheral neuropathy or spinal cord injury, postherpetic neuralgia, and fibromyalgia.
  • Treatment of pain.
efficacy
5.0  (2)
side effects
1.0  (2)
danger
0.0  (0)

UNK

WARNING: Consult a licensed physician in the appropriate field for medical treatment and drug prescription. Do not self medicate.


WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Felter's Materia Medica on Neuralgia

ÆSCULUS GLABRA
   The bark and fruit of Aesculus glabra, Willdenow (Nat. Ord. Sapindaceae). A small fetid tree common to the central portion of the United States. Common Names: Ohio Buckeye, Smooth Buckeye,... / ...to determine its status as a remedy for nervous disorders, and especially its control over visceral neuralgias. 1

BELLADONNA (Atropa belladonna)ATROP
   The (1) dried root and the (2) dried leaves and tops of Atropa Belladonna, Linné (Nat. Ord. Solanaceae). Europe and Central Asia; also... / ...abscesses, incipient and recurrent boils, buboes, hemorrhoids and fissures, inflamed glands, and in neuralgia, chronic rheumatism, lumbago, myalgia, pleurodynia, the chest pains of pulmonary tuberculo...1

CACTUS (Selenicereus spp.)
   The fresh, green stems and the flowers of Selenicereus grandiflorus (L.) Britt. & Rose (and other Selenicereus species—MM) (Cereus grandiflorus,... / ...ritant to the cardiac ganglia, producing thereby irritability, hyperaesthesia, arrythmia, spasm and neuralgia of the heart, and even carditis and pericarditis. According to E. M. Hale, M.D., it acts. ... / ...organ were held with a strong band, it is often the most prompt of all cardiac remedies. It is a good remedy in the heart troubles produced by to1

CAMPHORA
   A stearopten (having the nature of a ketone) derived from Cinnamomum Camphora. (Linné), Nees et Ebermeier (Nat. Ord. Lauraceae). China and... / ...ocations, for the relief of pain, stiffness, soreness and swelling, as in myalgia, facial and other neuralgias, and upon rheumatic joints, deep inflammations, chronic indurated glands and other indura... / ...due to gaseous distention of the stomach, or to nervous irritability. In occipital headache, from mental strain, or overstudy, small doses of 1

CANTHARIS
   The dried beetles, Cantharis vesicatoria (Linné), De Geer. (Ord. Coleoptera.) Southern Europe. Dose, 1 grain. Common Name: Spanish Fly; Synonym:... / ...pseated inflammation, to absorb inflammatory products, and to relieve local pain, as in intractable neuralgias and persistent headache. In Eclectic therapy the use of blisters is scarcely ever deemed ...1

CAPSICUM
   The ripe fruit, dried, of Capsicum frutescens, Linné (Nat. Ord. Solanaceae). Tropical America; also cultivated in most tropical countries. Dose,... / ...relief to so-called chronic rheumatic pains, and be applied in lumbago, pleurodynia and intercostal neuralgia. A stupe of hot water and capsicum applied to the nape of the neck sometimes relieves the ...1

CARYOPHYLLUS
   The unexpanded flowers (dried flower-buds) of Eugenia aromatica (Linné), O Kuntze. (Jambosa Caryophyllus (Sprengel) Niedenzu). (Nat. Ord.... / ...al pain and sometimes earache. Used pure or in ointments or liniments it relieves local pain, as in neuralgia, and in chronic eczema it allays itching, and is sometimes added to embrocations to give t... / ...oil of clove frequently relieves it. Eugenol. Derived from oil of clove and other sources may be given in doses of 1 to 3 minims.1

CHELIDONIUM
   The whole plant of Chelidonium majus, Linné (Nat. Ord. Papaveraceae). Europe naturalized in waste places in the United States. Dose, 1 to 60... / ...ich they depend. When hemorrhoids, splenic congestion, dyspepsia, headache, migraine, supra-orbital neuralgias and cough are dependent mostly upon the liver disorders helped by chelidonium, they are p...1

COLOCYNTHIS
   ...ng, twisting, boring, or tearing character, and if of the bowels, a desire to go to stool; visceral neuralgia, with cutting pain; dysentery, with tormina, and small passages of mucus, or diarrhoea wit...... bryonia should be considered. The dose should not be large enough to purge. Colocynth is useful in neuralgia of the viscera in the parts supplied by the splanchnic nerves, as neuralgic colic. Other n......hnic nerves, as neuralgic colic. Other nerve endings seem to respond to it, for it relieves ovarian neuralgia, orchialgia, and sometimes neuralgia of the fifth nerve, when the characteristic cutting p...1

CONIUM
   The full grown fruit, gathered green, of Conium maculatum, Linné (Nat. Ord. Umbelliferae). Europe and Asia; naturalized in the United... / ...the drug, it is best adapted to peripheral pain with excessive mobility. Thus it relieves spasmodic neuralgia, neuralgia from carious teeth, ovarian neuralgia, and gastralgia. In gastric ulcer it is q... / ...be applied and be given to relieve pain even when a cure is not possible. It relieves the pain of swollen mammae during the menstrual periods a1

CRATAEGUSCRAN6
   The ripe fruit and bark of (1) Crataegus Oxyacantha, Linné, and (2) other species of Crataegus. (Nat. Ord. Rosaceae) 1. England and other parts... / ... or without enlargement of the rings, rheumatism of the heart, dropsy depending on heart disorders, neuralgia of the heart, tachycardia, and in atheromatous conditions of the vessels. The exact indica... / ...trial; and as yet with no rational explanation of its reputed powers. The smaller doses are suggested as more likely to succeed than full doses.1

CYPRIPEDIUMCYAL10
   The rhizome and rootlets of Cypripedium pubescens, Swartz; and of Cypripedium parviflorum, Salisbury. (Nat. Ord. Orchidaceae.) Rich woods of the... / ...c Medicine Cypripedium. Dose, 5 to 60 drops. Specific Indications.—Insomnia, nervous irritability, neuralgia and delirium, all from atony; restlessness and muscular twitching, typhomania and tremors ... / ...Simple Syrup, enough to make 3 fluidounces. Mix. Sig.: Dose, 5 to 20 drops. If nausea occurs lessen the amount of, or omit the lobelia.1

DIOSCOREA
   The rhizome of Dioscorea villosa, Linné (Nat. Ord. Dioscoreaceae). A vine found throughout the United States. Dose, 5 to 60 grains. Common Names:... / ...ntraction of the muscular tissues, in cholera morbus, indigestion, and dysenteric tenesmus. Ovarian neuralgia and spasmodic dysmenorrhea sometimes yield quickly to it. In all disorders it seems best ... / ...does not dissolve calculi. Usually, while there is much tenderness in cases requiring dioscorea, the distress is gradually relieved by pressure.1

EUCALYPTUSEUAN12
   The leaves of Eucalyptus Globulus, Labillardiere. Collected from the older parts of the tree. (Nat. Ord. Myrtaceae.) A native tree of Australia;... / ...sed for many of the complications or results of chronic malarial cachexia, as periodic headache and neuralgia. It is only in occasional cases of malarial fever that it does a great deal of good, espec... / ...to indications as given above, eucalyptus is a very satisfactory and pleasant medicine. It is best given in syrup or glycerin.1

GAULTHERIA
   The leaves of Gaultheria procumbens, Linné (Nat. Ord. Ericaceae). Damp woods and sandy soils of eastern third of the United States. Common... / ... gonorrheal rheumatism, a specific gonorrheal arthritic infection. Small doses have relieved facial neuralgia and tic douloureux; and sometimes it exerts a soothing and antiseptic effect in acute gono... / ...of infants. Gaultheria is an agent of special value as a flavoring agent and preservative for water-dispensed medicines in the summer season. Fo1


WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Physician's Materia Medica on Neuralgia

ACONITE
   The tuber, also the leaves (unoflicial) of ACONITU M NAPELLUs, Lin. Actively poisonous. A powerful cardiac depressant acting thus as an arterial sedative; paralyzes sensory nerves and depresses respiratory centers. Used chiefly for its antipyretic effect and in treatment of neuralgia, rheumatism and cardiac hypertrophy; local ly, in liniments, for relief of pain. Dose, 0.015 to 0.12 Grm. (% to 2 grs.).2

AMMONIUM CHLORIDE
   Stimulant expectorant, alterative, hepatic stimulant. Used es pecially in bronchitis, acute or chronic, in hepatic torpor and catar rhal jaundice, in neuralgias and as a resolvent in glandular enlarge ments. Dose, as expectorant, 0.13 to 0.6 Grm. (2 to 10 grs.); as hepa tic stimulant, 0.6 to 2.0 Grm. (10 to 30 grs.).2

ARSENIC
   An active irritant poison. In small doses a powerful alterative. tonic, hematinic and antiperiodic. Prescribed in chronic cutaneous diseases, secondary syphilis, chorea, neuralgia and malarial fevers. a. Arsenous Bromide. Has been used especially in diabe tes. Dose, 0.0015 to 0.006 Grm. (1-40 to 1-10 gr.). b. Arsenous Chloride. Dose, 0.002 to 0.004 Grm. (1-30 to 1-15 am). For formulas see in Part II, Alteratives ( a) and Tonics (i). c. Arslenous iodide. Particularly useful in syphilis and obstin2

BLACK COHOSH (Cimicifuga)
   The rhizome and roots of CIMICIFUGA RACEMOs.-l, (L.) Nutt. Alterative, antispasmodic, uterine sedative. Prescribed in rheumatism, chorea, dysmenorrhea. ovarian neuralgia, asthma, spasmodic aflections gener'aliy, head ache, etc.2

CANNABIS INDICA (Indian Cannabis)
   The flowering tops of the pistillate plant of CANNABIs sa'r1vA, Lin., grown in the East Indies. Antispasmodic, analgesic, deliriant. aphrodisiac. Locally applied it is anti-pruritic. Prescribed in teta nus, in neuralgia, in insomnia and other conditions depending on anemia of the brain, in combating the morphine habit, etc. Dose, 0.2 to 0.6 Grm. (3 to 10 grs.) or more.2

COTO (Paracoto)
   The bark of an undetermined Bolivian tree, probably a species of NECTANDRA. The “Coto” commonly in use in this country is the variety which was formerly called “Paracoto.” Aromatic, astring ent, anodyne. Prescribed in obstinate diarrheas. in night sweats, neuralgia and rheumatism.2

GOLD
   The compounds of Gold have an action on the human system resembling that of mercurial salts. They modify and improve nu trition in cachectic conditions, stimulate the various emuctories and apparently give tone to the nervous system. They are hence prescribed in neurasthenia, in hysteria, in neuralgia (particularly ovarian) and in methomania. as well as in scrofula and chronic syphilis and rheumatism. a. Gold Bromide. Dose, 1-30 to 1-15 gr. The salt shows distinctly the sedative action of the br2

HORSE CHESTNUTAEHI
   The bark, also the fruit of AESCULUS HIPPOCASTANUM. Lin. Tonic, astringent, antiperiodic and slightly narcotic. Used in ma larial fevers and in neuralgias of malarial origin.2

PHENACETIN
   A derivative of NITRO-PHENOL. Analgesic. antipyretic. Prescribed for relief of pain in acute rheumatism, sciatica, gastralgia, migraine, dysmenorrhea, neuralgia. etc.; to reduce temperature and promote diaphoresis in fevers, and for a specific influence in diabetes. Dose, 0.12 to 0.60 Grm. (2 to 10 grs.).2

PLEURISY ROOT (Asclepias)
   The root of ASCLEPIAS TUBEROsA, Lin. Diaphoretic, expec torant, carminative, antipyretic; in large doses emetic and cathartic. Prescribed in the formative stage of fevers, in coryza and acute nasal catarrh of infants, in colliquative sweats of phthisis, in pleurodynia, intercostal neuralgia and rheumatism.2


WARNING: All medicines, drugs, plants, chemicals or medicial precedures below are for historical reference only. Many of these treatments are now known to be harmful and possibly fatal. Do not consume any plant, chemical, drug or otherwise without first consulting a licensed physician that practices medine in the appropriate field.

Physician's Therapeutics Memoranda on Neuralgia

NEURALGIA
   For immediate relief, prescribe acetanilid, phenacetin or anti pyrin usually conjoined with caffeine and potassium or sodium bro mide, sometimes gelsemium or cannabis indica; locally, liniments of aconite or chloroform; menthol, chloride of methyl spray; applica tions of electricity; hypodermatic injections of morphine and atropine (only when nothing else will serve). .In the general treatment, strychnine, arsenic and iron are the most generally useful remedies, but attention must always be give...2

SCIATICA
   General treatment for neuralgia. Hypodermatic iniections of atropine in heroic doses (1-20 grain) is highly recommended by some to cut short the attack. Others advise acupuncture or local massage or the ether spray, applied daily, or the hypodermatic use of morphine or of chloroform. In any case the hot water bottle and liniments of chloroform, aconite, methyl salicylate and menthol are remedies of value.2


References

1) Felter, Harvey Wickes, 1922, The Eclectic Materia Medica, Pharmacology and Therapeutics, Cincinnati, Ohio.
2) Nelson, Baker & Co., 1904, Physician's Handy Book of Materia Medica and Therapeustics, Detroit, Michigan.